Recurrent respiratory epithelial adenomatoid hamartoma of the nasal cavity

Kumar, Dhananjay; Handa, Kumud Kumar; Handa, Aru; Gautam, Poonam

doi:10.1080/08998280.2022.2086783

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…Te tumor excised from our patient had a characteristic cerebriform appearance of frm consistency. REAH has also been reported to coexist with infammatory polyps, as well as with inverted papilloma, which lends further uncertainty to its possible aetiology as either a reactive infammatory or an entirely neoplastic disease [8]. While an incisional biopsy may give a preliminary indication as to the nature of the mass (whether it is of malignant or benign aetiology), in practice, it is unlikely to preclude performing a defnitive excision.…”

Section: Discussionmentioning

confidence: 99%

Respiratory Epithelial Adenomatoid Hamartoma: An Uncommon Differential of Nasopharyngeal Tumor

Solaja,

Uche-Okonkwo,

Akinola

et al. 2023

Case Reports in Otolaryngology

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Respiratory epithelial adenomatoid hamartoma (REAH) is an uncommon tumor-like lesion that has been reported within the nose, paranasal sinuses, and less frequently in the nasopharynx. While it is believed to be benign, its clinical presentation, radiological characteristics, and microscopic features may closely mimic more aggressive tumors of the upper respiratory tract, potentially leading to needless life-altering treatment. Prior to now, there had been no reported cases of this lesion in West Africa. We present a 35-year-old male with persistent bilateral nasal obstruction, difficulty with swallowing, and bilateral reduction in hearing, whose CT findings were highly suggestive of a nasopharyngeal tumor, but upon biopsy and histology showed features most consistent with REAH. Surgery completely alleviated his symptoms with no clinical evidence of recurrence after a 1-year follow-up period.

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Section: Discussionmentioning

confidence: 99%

Respiratory Epithelial Adenomatoid Hamartoma: An Uncommon Differential of Nasopharyngeal Tumor

Solaja,

Uche-Okonkwo,

Akinola

et al. 2023

Case Reports in Otolaryngology

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Benign Paranasal Sinus Tumors

Luong

Yan

2023

Curr Otorhinolaryngol Rep

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Respiratory epithelial adenomatoid hamartoma in a child with nasal polyposis. Case report

Baranov,

Kotova,

Vyazmenov

et al. 2024

Consilium Medicum

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Benign and malignant formations of the nose and paranasal sinuses in the early stages of development are asymptomatic or manifest minor nonspecific signs, and therefore often remain unrecognized. Hamartoma is a tumor-like formation of a dysembriological nature, consisting of excessive tissues peculiar to the affected organ. Due to the rarity of the occurrence of hamartomas of the sinonasal region, especially in pediatric practice, their diagnosis may present certain difficulties, since they can mimic other formations, such as nasal polyps or inverted papilloma, may occur as an isolated formation in the nasal cavity, or in combination with chronic rhinosinusitis, nasal polyposis, allergic rhinosinusitis. Aim – to report a rare clinical case in pediatric practice of respiratory epithelial adenomatoid hamartoma associated with allergic rhinosinusitis and polyposis, display the relationship between the occurrence of respiratory epithelial adenomatoid hamartoma and chronic inflammation of the nasal cavity and paranasal sinuses, to carry out differential diagnosis with other exophytic aggressive lesions of the nasal cavity, combine and summarize available data on sinonasal hamartomas. The article describes a clinical case of respiratory epithelial adenomatoid hamartoma in a 17-year-old child with a previous 4-year follow-up with nasal cavity polyposis and a history of repeated polypotomy. The results of endoscopy and computed tomography of the nasal cavity and paranasal sinuses, the results of surgical intervention, as well as the conclusions of a histological examination of the tumor removed from the patient are presented. The authors analyzed the domestic and foreign literature, on the basis of which they presented a differential series of sinonasal hamartomas. Respiratory epithelial adenomatoid hamartoma is a rare pathological formation of the sinonasal region, which manifests itself as an isolated polypoid mass in the nasal cavity or as an accidental surgical finding in patients with chronic sinusitis. The association with nasal polyps supports the hypothesis that inflammation may be one of the inducing factors. Respiratory epithelial adenomatoid hamartoma, although rare, should be considered in the differential diagnosis of exophytic lesions of the nasal cavity. The tactics of treatment involves endoscopic removal of the formation within healthy tissues, which provides good long-term results, relapses are extremely rare.

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Recurrent respiratory epithelial adenomatoid hamartoma of the nasal cavity

Cited by 3 publications

References 6 publications

Respiratory Epithelial Adenomatoid Hamartoma: An Uncommon Differential of Nasopharyngeal Tumor

Respiratory Epithelial Adenomatoid Hamartoma: An Uncommon Differential of Nasopharyngeal Tumor

Benign Paranasal Sinus Tumors

Respiratory epithelial adenomatoid hamartoma in a child with nasal polyposis. Case report

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