Reduced acoustic noise in diffusion tensor imaging on a compact <scp>MRI</scp> system

Tan, Ek Tsoon; Hardy, Christopher J.; Shu, Yunhong; In, Myung Ho; Guidon, Arnaud; Huston, John; Bernstein, Matt A.; Foo, Thomas K.F.

doi:10.1002/mrm.26949

Cited by 7 publications

(4 citation statements)

References 46 publications

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“…Larger N in the of range 5 ≤ N ≤ 10 were often used to show that a new technical development is reproducible among subjects. Unlike for N = 1, the focus may then also be on measured region of interest (ROI)‐averaged quantitative values such as, for example, in Mueller et al, 15 Tan et al, 16 and Battiston et al 17 This N range allows the estimation of the intra‐ and inter‐scan reproducibility of ROI‐averaged quantitative values such as the ADC measured with a STEAM sequence in the liver 18 . The further benefits of using this N regimen is, on one hand, the possibility of pooling the data, for example, to obtain histograms of magnetization transfer parameters of the spinal cord, 17 and on the other hand, to assess the distributions of measured parameters such as temperatures with MR thermometry of the heart 19 .…”

Section: Discussionmentioning

confidence: 99%

Sample size estimation: Current practice and considerations for original investigations in MRI technical development studies

Hanspach

Nagel

Hensel

et al. 2020

Magnetic Resonance in Med

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Section: Discussionmentioning

confidence: 99%

Sample size estimation: Current practice and considerations for original investigations in MRI technical development studies

Hanspach

Nagel

Hensel

et al. 2020

Magnetic Resonance in Med

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“…This system can provide considerably reduced image distortion and increased spatial resolution for single‐shot EPI . In addition, the compact 3T (C3T) system provided a similar level of acoustic noise as whole‐body MRI systems, and passed standard image quality controls tests, such as those described by the American College of Radiology (ACR) …”

mentioning

confidence: 99%

Distortion‐free imaging: A double encoding method (DIADEM) combined with multiband imaging for rapid distortion‐free high‐resolution diffusion imaging on a compact 3T with high‐performance gradients

Tan

Trzasko

et al. 2019

Magnetic Resonance Imaging

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Background: Distortion-free, high-resolution diffusion imaging using DIADEM (Distortion-free Imaging: A Double Encoding Method), proposed recently, has great potential for clinical applications. However, it can suffer from prolonged scan times and its reliability for quantitative diffusion imaging has not been evaluated. Purpose: To investigate the clinical feasibility of DIADEM-based high-resolution diffusion imaging on a novel compact 3T (C3T) by evaluating the reliability of quantitative diffusion measurements and utilizing both the high-performance gradients (80 mT/m, 700 T/m/s) and the sequence optimization with the navigator acquisition window reduction and simultaneous multislice (multiband) imaging. Study Type: Prospective feasibility study. Phantom/Subjects: Diffusion quality control phantom scans to evaluate the reliability of quantitative diffusion measurements; 36 normal control scans for B 0 -field mapping; six healthy and two patient subject scans with a brain tumor for comparisons of diffusion and anatomical imaging. Field Strength/Sequence: 3T; the standard single-shot echo-planar-imaging (EPI), multishot DIADEM diffusion, and anatomical (2D-FSE [fast-spin-echo], 2D-FLAIR [fluid-attenuated-inversion-recovery], and 3D-MPRAGE [magnetization prepared rapid acquisition gradient echo]) imaging. Assessment: The scan time reduction, the reliability of quantitative diffusion measurements, and the clinical efficacy for high-resolution diffusion imaging in healthy control and brain tumor volunteers. Statistical Test: Bland-Altman analysis. Results: The scan time for high in-plane (0.86 mm 2 ) resolution, distortion-free, and whole brain diffusion imaging were reduced from 10 to 5 minutes with the sequence optimizations. All of the mean apparent diffusion coefficient (ADC) values in phantom were within the 95% confidence interval in the Bland-Altman plot. The proposed acquisition with a total offresonance coverage of 597.2 Hz wider than the expected bandwidth of 500 Hz in human brain could yield a distortion-free image without foldover artifacts. Compared with EPI, therefore, this approach allowed direct image matching with the anatomical images and enabled improved delineation of the tumor boundaries. Data Conclusion: The proposed high-resolution diffusion imaging approach is clinically feasible on C3T due to a combination of hardware and sequence improvements.

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“…During the process of image data collection, there may be more interference in the image due to the changes in environment and magnetic field [ 15 ]. Therefore, to improve the effect of image segmentation, the images had to be normalized and standardized when inputting the MR images into the model.…”

Section: Methodsmentioning

confidence: 99%

Automatic Segmentation of Magnetic Resonance Images of Severe Patients with Advanced Liver Cancer and the Molecular Mechanism of Emodin-Induced Apoptosis of HepG2 Cells under the Deep Learning

Zhao

Wang

et al. 2022

Journal of Healthcare Engineering

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To improve the accuracy of clinical diagnosis of severe patients with advanced liver cancer and enhance the effect of chemotherapy treatment, the U-Net model was optimized by introducing the batch normalization (BN) layer and the dropout layer, and the segmentation training and verification of the optimized model were realized by the magnetic resonance (MR) image data. Subsequently, HepG2 cells were taken as the research objects and treated with 0, 10, 20, 40, 60, 80, and 100 μmol/L emodin (EMO), respectively. The methyl thiazolyl tetrazolium (MTT) method was used to explore the changes in cell viability, the acridine orange (AO)/ethidium bromide (EB) and 4′,6-diamidino-2-phenylindole (DAPI) were used for staining, the Annexin V fluorescein isothiocyanate (FITC)/propidium iodide (PI) (Annexin V-FITC/PI) was adopted to detect the apoptosis after EMO treatment, and the Western blot (WB) method was used with the purpose of exploring the changes in protein expression levels of PARP, Bcl-2, and p53 in the cells after treatment. It was found that compared with the original U-Net model, the introduction of the BN layer and the dropout layer can improve the robustness of the U-Net model, and the optimized U-Net model had the highest dice similarity coefficient (DSC) (98.45%) and mean average precision (MAP) (0.88) for the liver tumor segmentation.

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Reduced acoustic noise in diffusion tensor imaging on a compact MRI system

Abstract: The feasibility of achieving reduced acoustic noise levels with whole-brain DTI on the C3T MRI was demonstrated. Magn Reson Med 79:2902-2911, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

Cited by 7 publications

References 46 publications

Sample size estimation: Current practice and considerations for original investigations in MRI technical development studies

Sample size estimation: Current practice and considerations for original investigations in MRI technical development studies

Distortion‐free imaging: A double encoding method (DIADEM) combined with multiband imaging for rapid distortion‐free high‐resolution diffusion imaging on a compact 3T with high‐performance gradients

Automatic Segmentation of Magnetic Resonance Images of Severe Patients with Advanced Liver Cancer and the Molecular Mechanism of Emodin-Induced Apoptosis of HepG2 Cells under the Deep Learning

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