Reduced Mesopic and Photopic Foveal Contrast Sensitivity in Glaucoma

Lahav, Karen; Levkovitch-Verbin, Hani; Belkin, Michael; Glovinsky, Yoseph; Polat, Uri

doi:10.1001/archophthalmol.2010.332

Cited by 59 publications

(66 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although previous work has examined CS in glaucoma patients using a variety of tests, 15, 21–23 the present report is the first to evaluate CS using the digital MSSS-II display that has recently become commercially available. We show that the large letter CS measurements assessed with the MSSS-II are correlated significantly with standard HVF MD measurements, suggesting that large letter CS may be a useful adjunct test of visual function in glaucoma patients.…”

Section: Discussionmentioning

confidence: 99%

M&S Smart System Contrast Sensitivity Measurements Compared With Standard Visual Function Measurements in Primary Open-Angle Glaucoma Patients

Liu

McAnany

Aref

et al. 2017

Journal of Glaucoma

View full text Add to dashboard Cite

Purpose To evaluate the nature and extent of letter contrast sensitivity (CS) deficits in glaucoma patients using a commercially available computer-based system (MSSS-II) and to compare the letter CS measurements to standard clinical measures of visual function. Methods Ninety-four subjects with primary open-angle glaucoma participated. Each subject underwent visual acuity, letter CS, and standard automated perimetry (SAP) testing (Humphrey SITA 24-2). All subjects had a best-corrected visual acuity (BCVA) of 0.3 log MAR (20/40 Snellen equivalent) or better and reliable SAP (fixation losses, false positives, and false negatives < 33%). Contrast sensitivity functions (CSFs) were estimated from the letter CS and BCVA measurements. The area under the CSF (AUCSF), which is a combined index of CS and BCVA, was derived and analyzed. Results The mean (± SD) BCVA was 0.08 ± 0.10 log MAR (approximately 20/25 Snellen equivalent), the mean CS was 1.38 ± 0.17, and the mean HVF MD was −7.22 ± 8.10 dB. CS and HVF MD correlated significantly (r = 0.51, p < 0.001). BCVA correlated significantly with large letter CS (r = −0.22, p = 0.03), but not with HVF MD (r = −0.12, p = 0.26). A subset of the subject sample (approximately 20%) had moderate to no field loss (≤−6 dB MD) and minimal to no BCVA loss (≤0.3 log MAR), but had poor letter CS. AUCSF was correlated significantly with HVF MD (r = 0.46, p < 0.001). Conclusions The present study is the first to evaluate letter CS in glaucoma using the digital MSSS-II display. Letter CS correlated significantly with standard HVF MD measurements, suggesting that letter CS may provide a useful adjunct test of visual function for glaucoma patients. Additionally, the significant correlation between HVF MD and the combined index of CS and BCVA (AUCSF) suggests that this measure may also be useful for quantifying visual dysfunction in glaucoma patients.

show abstract

Section: Discussionmentioning

confidence: 99%

M&S Smart System Contrast Sensitivity Measurements Compared With Standard Visual Function Measurements in Primary Open-Angle Glaucoma Patients

Liu

McAnany

Aref

et al. 2017

Journal of Glaucoma

View full text Add to dashboard Cite

show abstract

“…As no morphological macular disorder was seen in OCT images postoperatively, invisible damage in the visual pathway caused by macular detachment was detected as reduced CS, and CS may be affected by macular damage under unusual conditions such as glare and higher spatial frequency. Although CS is affected by lens status and various eye conditions such as glaucoma, corneal disease, and retinal disease [6,7,8], patients with those diseases were not included in this study, and no difference in the proportion of lens-sparing vitrectomy cases was postoperatively observed between our 2 groups. Our data show that CS measurement has the ability to detect subtle visual dysfunction in macular-off RRD patients with postoperative BCVA ≥1.0.…”

Section: Discussionmentioning

confidence: 99%

Contrast Sensitivity after Pars Plana Vitrectomy: Comparison between Macula-On and Macula-Off Rhegmatogenous Retinal Detachment

Kawamura

Fujikawa²,

Sawada³

et al. 2016

Ophthalmic Res

View full text Add to dashboard Cite

Purpose: To evaluate the contrast sensitivity (CS) of eyes successfully repaired by vitrectomy for rhegmatogenous retinal detachment (RRD) with or without preoperative macular involvement. Methods: In this retrospective, consecutive, interventional case series, 109 eyes received primary vitrectomy for RRD, of which 36 with at least 12 months of follow-up and a best-corrected visual acuity (BCVA) ≥1 at 12 months postoperatively were investigated. The main outcome measurements were BCVA and CS at 12 months postoperatively. Patients with macula-on RRD preoperatively were included in the macula-on group, and patients with macula-off RRD preoperatively were included in the macula-off group. The between-group difference in CS under evening vision conditions was measured with a Takagi glare tester CGT-2000 at 6 visual angles and 13 contrast levels with and without glare. Results: CS was significantly lower in the macula-off group for targets with visual angles of 1.6, 1.0, and 0.64° with glare (p < 0.05) and for the target with a visual angle of 0.64° without glare (p < 0.05). Conclusions: CS in the higher spatial frequency range (especially with glare) is reduced in macula-off RRD patients with good postoperative BCVA compared to macula-on RRD patients with good postoperative BCVA.

show abstract

“…For instance, visual acuity (VA) is considered an essential part of any eye examination [2] and it is used in the screening of refractive errors [3] and amblyopia [4]. On the other hand, the Contrast Sensitivity Function (CSF) is considered an additional test for specialized clinical evaluation, and has been generally accepted as a better predictor of visual performance than high contrast VA [5][6][7].…”

Section: Introductionmentioning

confidence: 99%