1994
DOI: 10.1053/ai.1994.v94.a55222
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Reduced secretion of IgA to skin surface of patients with atopic dermatitis

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Cited by 62 publications
(12 citation statements)
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“…Accordingly, AD patients show significantly lower sweat rates upon moderate thermal stress (29). Differences in the composition of sweat, with reduced secretion of IgA (30) and altered sweat electrolyte concentrations (31) in children with AD, have been described. Therefore, our findings underline specific differences in sweating that may be related to the high incidence of skin infections.…”
Section: Discussionmentioning
confidence: 99%
“…Accordingly, AD patients show significantly lower sweat rates upon moderate thermal stress (29). Differences in the composition of sweat, with reduced secretion of IgA (30) and altered sweat electrolyte concentrations (31) in children with AD, have been described. Therefore, our findings underline specific differences in sweating that may be related to the high incidence of skin infections.…”
Section: Discussionmentioning
confidence: 99%
“…The present study confirms that the skin surface of patients with AD is widely colonized by a higher number of microbial populations, particularly of S. aureus , than that of control patients (Table 2). 12 Existence of higher population levels of bacteria on atopic skin may be caused by decreasing sphingomyelinase and ceramide, 13 reduced secretion of IgA, high pH and salt‐rich sweat 14 . Williams et al .…”
Section: Discussionmentioning
confidence: 99%
“…The patient was diagnosed according the clinical criteria (18,19), past history of other atopic disease, high total IgE level (22,100 units/ml), and typical eczematous skin lesions on the face, neck, and extremities.…”
Section: Materials-mentioning
confidence: 99%