Background: Much of the world's population suffers from knee pain. Treatment options are too extreme (surgery), have side-effects (drugs), or take too long (physical therapy). Research has shown that acupuncture can provide modest relief of knee pain. This article presents ways to improve the effectiveness of acupuncture for treating knee pain. Using 3 composite ''cases,'' the author offers specific modifications to acupuncture treatments-particularly palpatory techniques-that produce more-successful relief of patients' knee pain. Cases: Analyzing 3 composites of multiple similar typical cases, the author compares what made the treatments more successful than would be statistically anticipated. Composite case 1: Women, older than, 50 had knee osteoarthritis (OA), periodic pain, more at night and during weather changes. Composite case 2: Men and women, in their 40s and early 50s, had mild knee arthritis, and were given injections to relieve pain that was mild-to-moderate and worse at night. Composite case 3: Men between their late 20s and early 40s, experienced knee pain 1-4 times per week, with some patients reporting knee buckling after some activities. Results: Palpation of these patients' knees revealed the causes of their knee pain-spasms, adhesions, and/or fibrosis-and the patients were treated with individually selected points based on results of the Four Examinations. Most obtained relief lasting from 4 months to 2 years. Conclusions: Mainstream acupuncture treatments rarely involve using the Four Examinations of Traditional Chinese Medicine. Instead, these treatments involve common point selections for addressing knee pain or moreadvanced approaches, such as Five Elements or Zang-Fu pattern diagnosis, often disregarding such basic but essential diagnostic techniques as visual inspection and particularly palpation. According to the Four Examinations, OA is not often the cause of knee pain; instead, adhesions and fibrosis of the soft tissues around the knee joint cause nerve entrapments, and knee pain is referred from those sources. While muscle fibrosis is well-known to cause pain, it is rarely addressed in detail in acupuncture literature. If palpation of the soft tissues around the knee joint evokes a patient's pain-thus, locating the nerve entrapment in each specific case precisely-this allows the clinician to insert acupuncture needles into the soft-tissue fibrosis. This needling could improve the clinical outcomes of acupuncture treatment of knee pain significantly, providing shorter-as well as longer-term relief.