Reduction of Aflatoxin M<sub>1</sub> from Artificially Contaminated Milk Using Ultrafiltration and Diafiltration

Higuera‐Ciapara, I.; Esqueda-Valle, M.; Nieblas, Jose

doi:10.1111/j.1365-2621.1995.tb09847.x

Cited by 7 publications

(4 citation statements)

References 11 publications

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“…Milk proteins were concentrated during UF from an average 3.3696 in raw whole milk to 10.08% in VCR 3. This removal phenomenon has been described for penicillin G (Kosikowski and Jimenez-Flores 1985) and aflatoxin MI (Higuera-Ciapara et al 1995).…”

Section: Removal Of Sulfamethazine From Unhomogenized Milkmentioning

confidence: 64%

“…1982). Many experiments have been carried out on whole milk (Glover 1971) and skim milk (Fenton-May et al 1972) and diafiltration has been previously shown to be effective in the removal of some toxic residues found in milk (Kosikowski and Jimenez Flores 1987;Higuera-Ciapara et al 1995). Due to the frequency and level of contamination with SMZ in fluid milk and the significant risk to human health posed by its residues, the discontinuous diafiltration may be ideal for separation of low-molecular weight contaminants from milk.…”

Section: Introductionmentioning

confidence: 99%

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Removal of Sulfamethazine From Artificially Contaminated Milk by Ultrafiltration

Higuera‐Ciapara

Esqueda-Valle

Nieblas

1997

J Food Processing Preservation

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The effect of discontinuous diafiltration (DD) on removal of sulfamethazine (SMZ) from raw whole and homogenized milk was studied. Milk was artificially contaminated with concentrations of SMZ varying from 20 to 90 μg/L. A hollow‐fiber membrane with a molecular weight cut‐off of 10,000 daltons was used for all experimental runs at 55C. The removal pattern of SMZ was influenced (P<0.05) by both the initial concentration and the homogenization process. Homogenization increased the removal of SMZ from milk. The DD process resulted in concentrates with residual levels of SMZ <10 μg/L (FDA action level). SMZ was not detected in reconstituted retentates resulting from milk originally up to 30 μg/L.

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Section: Removal Of Sulfamethazine From Unhomogenized Milkmentioning

confidence: 64%

Section: Introductionmentioning

confidence: 99%

Removal of Sulfamethazine From Artificially Contaminated Milk by Ultrafiltration

Higuera‐Ciapara

Esqueda-Valle

Nieblas

1997

J Food Processing Preservation

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“…It was found that ultrafiltration and diafiltration reduced M 1 concentration in raw milk up to 43.8% and 25%, respectively, due to the small size (328 D) of AFM 1 . On the other hand, acidification and homogenization did not affect the level of M 1 in milk (Higuera-Ciapara et al, 1995). Nevertheless, these physical control practices are not only expensive and time consuming but also unable to completely eliminate aflatoxins from food and feed.…”

Section: Physical Controlmentioning

confidence: 98%

An Overview of Aflatoxins in the Developing World Regarding Food Security and Safety

2020

NJBS

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Food security and food safety are alarming issues in the developing world. Aflatoxins are among the naturally occurring poisons that are fatal for all animals due to their carcinogenic potential. Recent studies have shown the correlation of these toxins with food chains. This correlation has been found to be more significant in developing countries as compared to developed countries. Since the discovery of aflatoxins, great efforts have been exerted to investigate their biochemical nature, biosynthesis, mode of pathogenesis and health-associated effects. However, no sound remedy has yet been designed to completely control their development. The main purpose of this review is to consolidate the findings of published studies on the status of aflatoxins in developing countries, including recent perspectives in this field. The areas that need to be elucidated further are also highlighted

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“…They are direct hazard to human health (Butler, 1974 andKrogh, 1989). The aflatoxins are highly toxic fungal metabolites and may cause a variety of adverse health effects, e.g., liver cancer in animal and man, (Mercado et al, 1991 andHiguera-Clapara et al, 1995). Aflatoxins, especially aflatoxin B1 is considered the most potent carcinogenic in all naturally produced toxins.…”

Section: Introductionmentioning

confidence: 99%

CHEMICAL CHANGES IN SOME LEGUME SEEDS INFECTED WITH Aspergillus flavus PRODUCING AFLATOXIN

Eisa

2000

Journal of Soil Sciences and Agricultural Engineering

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Three legume seeds, namely, winged bean, kidney bean and lentil, were contaminated with A. flavus. The infected seeds were incubated at 28C for 10 days, with moisture content of 20-30%, where suitable amount of aflatoxin was elaborated. The samples were subjected to chemical analysis before and after contamination. Proximate analysis of infected samples showed that crude protein and fibers were increased, while crude lipids, ash and total carbohydrates were decreased comparing with healthy samples. Percentage values of protein fractions were increased in infected samples, whereas water soluble protein showed high increase, salt soluble protein showed moderate increase, while non soluble protein gave slight increase. The values of amino acids in infected seeds were increased in some amino acids and decreased in another acids. Cystine, arginine, glycine, threonine, alanine and phenylalanine were increased in infected seeds.However, aspartic, serine, methaionine, valine, leucine and isolucine were decrease. Arginine showed the highest increase in infected winged bean. It increased from 2582.10 to 3950.70 mg/100 gm sample. Methionine showed the highest decrease in infected lentil. It decreased from 1600.8 to 1144.0 mg/100 gm sample. Fatty acids analysis of legume lipids revealed that oleic, linoleic and linolenic fatty acids were more affected by fungal infection. Oleic and linoleic were increased in infected samples, however linolenic was decreased. The fate of aflatoxins during soaking and boiling infected seeds was investigated. The aflatoxines were fractionated and estimated before and after treatments. Fractionation of aflatoxins on TLC showed that winged bean and kidney bean contained two aflatoxins compounds in untreated samples, one of them was B1. After soaking of these samples the same two compounds were also found. Aflatoxins of winged bean, which was boiled, contained one aflatoxin while the other compound was disappeared. However, aflatoxins of untreated lentil showed one aflatoxin (B1), this compound disappeared after treatment this sample by boiling. The results revealed also that aflatoxins of winged bean, with initial value of 31.66 g/100 gm sample, was reduced to 36.83% by soaking and 82.06% by boiling. Aflatoxin of kidney bean, with initial value of 23.99 g/ 100 gm sample, was lossed to 39.03% by soaking and 59.08% by boiling. However, aflatoxins of lentil, with initial value of 19.33 g/100 gm sample, was reduced to 91.0% by soaking and removed completely by boiling.

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Reduction of Aflatoxin M₁ from Artificially Contaminated Milk Using Ultrafiltration and Diafiltration

Abstract: The effect of ultrafiltration-diafiltration (UF-DF) on removal of aflatoxin M, (AFM,) from raw whole, homogenized and acidified milk was studied. Milk was artificially augmented with concentrations of AFM, varying from 0.5 to 3.5 pg/L. The removal of AFM, was influenced (p Show more

Cited by 7 publications

References 11 publications

Removal of Sulfamethazine From Artificially Contaminated Milk by Ultrafiltration

Removal of Sulfamethazine From Artificially Contaminated Milk by Ultrafiltration

An Overview of Aflatoxins in the Developing World Regarding Food Security and Safety

CHEMICAL CHANGES IN SOME LEGUME SEEDS INFECTED WITH Aspergillus flavus PRODUCING AFLATOXIN

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Reduction of Aflatoxin M1 from Artificially Contaminated Milk Using Ultrafiltration and Diafiltration

Abstract: The effect of ultrafiltration-diafiltration (UF-DF) on removal of aflatoxin M, (AFM,) from raw whole, homogenized and acidified milk was studied. Milk was artificially augmented with concentrations of AFM, varying from 0.5 to 3.5 pg/L. The removal of AFM, was influenced (p Show more

Cited by 7 publications

References 11 publications

Removal of Sulfamethazine From Artificially Contaminated Milk by Ultrafiltration

Removal of Sulfamethazine From Artificially Contaminated Milk by Ultrafiltration

An Overview of Aflatoxins in the Developing World Regarding Food Security and Safety

CHEMICAL CHANGES IN SOME LEGUME SEEDS INFECTED WITH Aspergillus flavus PRODUCING AFLATOXIN

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Reduction of Aflatoxin M₁ from Artificially Contaminated Milk Using Ultrafiltration and Diafiltration