Reduction of body weight, body fat mass, and serum leptin levels by addition of new beverage in normal diet of obese subjects

Abstract

Vinegar and garlic are well‐known functional foods used in reducing obesity, Hence, a new beverage was developed from dates vinegar and garlic juice in order to reduce obesity. Current investigation focused on 85 obese adults. Participants consumed 500 mL of either beverage or placebo daily into their normal diet for a period of 10 weeks. Body weight, body mass index (BMI), waist circumference, visceral fat area (VFA), serum lipid profile, serum leptin, alanine transaminase (ALT), aspirate transaminase (AST), urea, and creatinine levels were analyzed before and after the treatment. The outcomes indicated that new beverage reduced the body weight (73.9 ± 6.7 to 69.6 ± 5.8 kg, p = .002), body fat ratio (29.8 ± 5.4 to 28.1 ± 4.2%, p = .004), and serum leptin (36.25 ± 3.2 to 31.12 ± 3.7 ng/mL, p = .002), and can therefore play a critical role in preclusion of metabolic syndrome. Practical applications Dates and garlic, compared with other fruits, are rich source of phenolic compounds and fibers. Researchers have claimed that extracts of dates fruit and garlic are effective in reducing obesity and prevention of metabolic syndrome. Thus, this study was conducted to determine the effects of a new beverage made of dates vinegar and garlic juice on obesity by assessing body weight, BMI, body fat mass, blood pressure, lipid profile, and liver markers. The results of this clinical trial present a latent approach to the avoidance of obesity and provide a possible source of phenolic compounds. This new beverage is suggested as a dietary supplement for the prevention of obesity and metabolic syndrome.

Preliminary study to evaluate the phytochemicals and physiochemical properties in red and black date's vinegar

“…Presently, consumer concern in healthy food is on the rise due to the advancement in the field of functional foods formulation. Moreover, consumers are demanding value‐added foodstuff with new attributes and this has led to several studies with the aim of optimizing health benefits of food products (Ali, Ma, Rashid, Ayim, & Wali, ; Ubeda et al, ). Various researchers have reported the association among the ingestion of vegetables and fruits in reducing the risk of cancer, cardiovascular disease, inflammation, and metabolic syndrome‐related complications (Hung et al, ).…”

“…Dates contain fiber vital mineral (iron, selenium fluorine, and calcium) and vitamins (Vayalil, ). Results have shown that extracts from dates have exposed free radical scavenging activity, immunomodulatory, and antimutagenic activities, (Allaith, ; Khan, Sarwar, Wahab, & Haleem, ) and dates have cardioprotective, anti‐inflammatory, antiobesity, and antihypertensive effects (Ali, Ma, Ayim, & Wali, ; Ali, Ma, Rashid, et al, ). In the past, dates' vinegar did not receive the attention it deserves due to limited literature about the fruit.…”

Sub‐chronic consumption of a phenolic‐rich avocado paste extract induces GLP‐1‐, leptin‐, and adiponectin‐mediated satiety in Wistar rats

“…Since the animals’ percentage of adipose tissue was similar among all groups (Figure 3), it can be suggested that any changes on these hormones were due to direct effects of the diets’ macronutrient composition and/or phenolic supplementation. In obese adults, PCs from dates and vinegar were shown to increase serum leptin concentration, when consuming them in a beverage during a ten‐week period (Ali et al., 2018). Montalbano et al.…”