Redundancy gain in simple reaction time following partial and complete callosotomy

Corballis, Michael C.; Corballis, Paul M.; Fabri, Mara

doi:10.1016/s0028-3932(03)00152-0

Cited by 42 publications

(34 citation statements)

References 38 publications

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“…A possible neural mechanism for facilitation and interference between global and local processing levels involves interhemispheric interactions (Corballis et al, 2004;Forster and Corballis, 2000). Evidence from a split-brain study (Robertson et al, 1993) suggests that the corpus callosum mediates local-global interference.…”

Section: The Role Of the Corpus Callosum In Interference And Facilitamentioning

confidence: 99%

Local–global interference is modulated by age, sex and anterior corpus callosum size

et al. 2007

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To identify attentional and neural mechanisms affecting global and local feature extraction, we devised a global-local hierarchical letter paradigm to test the hypothesis that aging reduces functional cerebral lateralization through corpus callosum (CC) degradation. Participants (37 men and women, 26-79 years) performed a task requiring global, local, or global+local attention and underwent structural MRI for CC measurement. Although reaction time (RT) slowed with age, all participants had faster RTs to local than global targets. This local precedence effect together with greater interference from incongruent local information and greater response conflict from local targets each correlated with older age and smaller callosal genu (anterior) areas. These findings support the hypothesis that the CC mediates lateralized local-global processes by inhibition of task-irrelevant information under selective attention conditions. Further, with advancing age smaller genu size leads to less robust inhibition, thereby reducing cerebral lateralization and permitting interference to influence processing. Sex was an additional modifier of interference, in that callosum-interference relationships were evident in women but not in men. Regardless of age, smaller splenium (posterior) areas correlated with less response facilitation from repetition priming of global targets in men, but with greater response facilitation from repetition priming of local targets in women. Our data indicate the following dissociation: Anterior callosal structure was associated with inhibitory processes (i.e., interference from incongruency and response conflict), which are vulnerable to the effects of age and sex, whereas posterior callosal structure was associated with facilitation processes from repetition priming dependent on sex and independent of age.

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Section: The Role Of the Corpus Callosum In Interference And Facilitamentioning

confidence: 99%

Local–global interference is modulated by age, sex and anterior corpus callosum size

et al. 2007

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“…Thut et al 1999;Tettamanti et al 2002;Zaidel 2003, 2004), or already at a visual level (e.g. Brown et al 1994;Ipata et al 1997;Murray et al 2001; see also Corballis et al 2003 for supporting evidence from patients with partial callosal lesions/sections). Others, applying a case-study approach to the analysis of electrophysiological data, report how visuo-motor routing varies both between individuals and also as a function of reaction time (Saron et al 2003a, b).…”

Section: Introductionmentioning

confidence: 97%

Visuo-motor pathways in humans revealed by event-related fMRI

et al. 2005

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Whether different brain networks are involved in generating unimanual responses to a simple visual stimulus presented in the ipsilateral versus contralateral hemifield remains a controversial issue. Visuo-motor routing was investigated with event-related functional magnetic resonance imaging (fMRI) using the Poffenberger reaction time task. A 2 hemifield · 2 response hand design generated the ''crossed'' and ''uncrossed'' conditions, describing the spatial relation between these factors. Both conditions, with responses executed by the left or right hand, showed a similar spatial pattern of activated areas, including striate and extrastriate areas bilaterally, SMA, and M1 contralateral to the responding hand. These results demonstrated that visual information is processed bilaterally in striate and extrastriate visual areas, even in the ''uncrossed'' condition. Additional analyses based on sorting data according to subjects' reaction times revealed differential crossed versus uncrossed activity only for the slowest trials, with response strength in infero-temporal cortices significantly correlating with crossed-uncrossed differences (CUD) in reaction times. Collectively, the data favor a parallel, distributed model of brain activation. The presence of interhemispheric interactions and its consequent bilateral activity is not determined by the crossed anatomic projections of the primary visual and motor pathways. Distinct visuo-motor networks need not be engaged to mediate behavioral responses for the crossed visual field/ response hand condition. While anatomical connectivity heavily influences the spatial pattern of activated visuomotor pathways, behavioral and functional parameters appear to also affect the strength and dynamics of responses within these pathways.

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“…Clearly, with two targets contributing activation toward the same threshold, the response is activated more rapidly than when there is only one target contributing activation. Although the concept of coactivation originally proposed by Miller (1982Miller ( , 1986 was not necessarily linked to neural activity, several more recent studies on brain-damaged patients and with neuroimaging techniques have argued convincingly that it is equivalent of neural summation and interhemispheric interaction (Corballis 1998;Corballis et al 2002Corballis et al , 2003Iacoboni et al 2000;Iacoboni and Zaidel 2003;Marzi et al 1996;Miniussi et al 1998;Reuter-Lorenz et al 1994;Corballis 2002, 2003;Savazzi and Marzi 2002).…”

Section: Introductionmentioning

confidence: 99%

Functional asymmetry and interhemispheric cooperation in the perception of emotions from facial expressions

et al. 2005

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The present study used the redundant target paradigm on healthy subjects to investigate functional hemispheric asymmetries and interhemispheric cooperation in the perception of emotions from faces. In Experiment 1 participants responded to checkerboards presented either unilaterally to the left (LVF) or right visual half field (RVF), or simultaneously to both hemifields (BVF), while performing a pointing task for the control of eye movements. As previously reported (Miniussi et al. in J Cogn Neurosci 10:216-230, 1998), redundant stimulation led to shorter latencies for stimulus detection (bilateral gain or redundant target effect, RTE) that exceeded the limit for a probabilistic interpretation, thereby validating the pointing procedure and supporting interhemispheric cooperation. In Experiment 2 the same pointing procedure was used in a go/no-go task requiring subjects to respond when seeing a target emotional expression (happy or fearful, counterbalanced between blocks). Faster reaction times to unilateral LVF than RVF emotions, regardless of valence, indicate that the perception of positive and negative emotional faces is lateralized toward the right hemisphere. Simultaneous presentation of two congruent emotional faces, either happy or fearful, produced an RTE that cannot be explained by probability summation and suggests interhemispheric cooperation and neural summation. No such effect was present with BVF incongruent facial expressions. In Experiment 3 we studied whether the RTE for emotional faces depends on the physical identity between BVF stimuli, and we set a second BVF congruent condition in which there was only emotional but not physical or gender identity between stimuli (i.e. two different faces expressing the same emotion). The RTE and interhemispheric cooperation were present also in this second BVF congruent condition. This shows that emotional congruency is the sufficient condition for the RTE to take place in the intact brain and that the cerebral hemispheres can interact in spite of physical differences between stimuli.

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Redundancy gain in simple reaction time following partial and complete callosotomy

Cited by 42 publications

References 38 publications

Local–global interference is modulated by age, sex and anterior corpus callosum size

Local–global interference is modulated by age, sex and anterior corpus callosum size

Visuo-motor pathways in humans revealed by event-related fMRI

Functional asymmetry and interhemispheric cooperation in the perception of emotions from facial expressions

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