Reference Ranges for Serum Uric Acid among Healthy Assamese People

Abstract

This study was designed to establish reference ranges for serum uric acid among healthy adult Assamese population. Samples from 1470 aged 35–86 years were used to establish age and sex related reference range by the centile method (central 95 percentile) for serum uric acid level. There were 51% (n = 754) males and 49% (n = 716) females; 75.9% (n = 1115) of them were from urban area and the rest 24.1% (n = 355) were from the rural area. Majority of the population were nonvegetarian (98.6%, n = 1450) and only 1.4% (n = 20) were vegetarian. The mean age, weight, height, and uric acid of the studied group were 53.6 ± 11.3 years, 62.6 ± 10.5 kg, 160 ± 9.4 cm, and 5.5 ± 1.4 mg/dL, respectively. There is a statistically significant difference in the mean value of the abovementioned parameters between male and female. The observed reference range of uric acid in the population is 2.6–8.2 mg/dL which is wider than the current reference range used in the laboratory. Except gender (P < 0.0001), we did not find any significant relation of uric acid with other selected factors.

Roles of serum uric acid, prolactin levels, and psychosocial factors in oral lichen planus

“…For example, Das et al reported that serum UA ranged from 2.6 to 8.2 mg/dL in a healthy Assamese population (27). In the present cohort, UA ranged from 2.4 to 6.2 mg/dL.…”

Association between serum uric acid and arterial stiffness in a low-risk, middle-aged, large Korean population

“…Among Koreans, the reported reference level of SUA was 5.37 ± 1.106 mg/dL in men and 3.87 ± 0.745 mg/dL in women, [ 27 ] which seems to be slightly lower compared to those of other Asian countries. [ 28 , 29 ] Those discrepancies may come from nutritional status and other physical conditions. Thus, our results may not be generalizable to other ethnic groups with different demographics.…”

Distribution of serum amyloid A and establishment of reference intervals in healthy adults

“…Because the reference interval is also susceptible to methodological differences, population characteristics and geographical differences, the reference interval provided by the reagent manufacturer has limitations, so a laboratory self-built reference interval is particularly important. 12,13 Unfortunately, so far there have been a few reports about the establishment of SAA reference intervals in humans. 14,15 Hence, the present study was conducted through recruitment, sampling, and measurement.…”