Reflections of Hunger and Satiation in the Structure of Temporal Organization of Slow Electrical and Spike Activities of Fundal and Antral Stomach Muscles in Rabbits

Abstract

Manifestations of hunger and satiation in myoelectric activity patterns in different portions of the stomach were studied in chronic experiments. The state of hunger manifested in the structure of temporal organization of slow electric activity of muscles in the stomach body and antrum in the form of bimodal distributions of slow electric wave periods, while satiation as unimodal distribution. In hunger-specific bimodal distribution of slow electric wave periods generated by muscles of the stomach body and antrum, the position of the first maximum carries the information about oncoming food reinforcement, since this particular range of slow wave fluctuations determines temporal parameters of slow electric activity of muscles in all stomach regions in the course of subsequent successive food-procuring behavior. Under conditions of hunger, the pacemaker features of muscles in the lesser curvature are realized incompletely. Complete realization is achieved in the course of food intake and at the state of satiation.

Characteristics of Rabbit Food-Procuring Behavior as an Indicator of Changes in the Level of Hunger Motivation

“…In this connection, there is a long-felt need to develop the method of HML change measurements in the course of its satisfaction of nutritional need using weight, temporal and rate EFPB characteristics. This method will allow not only assessment of various factor effects on nutritional motivation [1,2,4], but also afford ample opportunities for investigations of eating behavior pharmacological correction [5,8].…”