Regeneration of a Full-thickness Defect of Rotator Cuff Tendon with Freshly Thawed Umbilical Cord-Derived Mesenchymal Stem Cells in a Rat Model

Abstract

The authors have withdrawn this preprint due to erroneous posting.

Exosomes isolated from melatonin-stimulated mesenchymal stem cells improve kidney function by regulating inflammation and fibrosis in a chronic kidney disease mouse model

“…The MT and PSR stained area were measured using Image J software with installed NII plugin (National Institutes of Health, MD, USA). 4…”

“…Mesenchymal stem cells (MSCs) have emerged as a promising therapeutic strategy in regenerative medicine. 4 MSCs isolated from various tissues such as the bone marrow (BM), adipose (AD), muscle, and umbilical cord (UC), have the ability to differentiate into various cells such as osteocytes, endothelial cells, and chondrocytes. 5,6 The paracrine effect of MSCs is also known to not only induce tissue regeneration without fibrosis, but also to inhibit inflammation.…”

“…5,6 The paracrine effect of MSCs is also known to not only induce tissue regeneration without fibrosis, but also to inhibit inflammation. 4,6,7 However, the use of MSCs is associated with some risks because they can induce immune rejection responses and differentiate into cells other than those intended, especially tumor cells. 7,8 Moreover, the engraftment rate of cells after MSC transplantation is low.…”