Regenerative medicine in osteoarthritis- a new chance for knee osteoarthritis patients

Marc, Jean-Francois

doi:10.4172/1758-4272.1000198

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“…This impairs clinical implementation and diffusion of regenerative therapies [93]. The question that arises is if regenerative medicine is able to provide an alternative to more conventional therapies [94,95]. Therefore, in the future, the conduction of more complete trials will be needed, in terms of large-scale and long-term follow-up and comparison with the control group.…”

Section: Future Perspectivesmentioning

confidence: 99%

Articular Cartilage Regeneration in Osteoarthritis

Roseti

Desando

Cavallo

et al. 2019

Cells

155

103

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There has been considerable advancement over the last few years in the treatment of osteoarthritis, common chronic disease and a major cause of disability in older adults. In this pathology, the entire joint is involved and the regeneration of articular cartilage still remains one of the main challenges, particularly in an actively inflammatory environment. The recent strategies for osteoarthritis treatment are based on the use of different therapeutic solutions such as cell and gene therapies and tissue engineering. In this review, we provide an overview of current regenerative strategies highlighting the pros and cons, challenges and opportunities, and we try to identify areas where future work should be focused in order to advance this field.

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Section: Future Perspectivesmentioning

confidence: 99%