Based on the results of biogeochemical studies in the territory of Western Predkamye (Pestrechinsky, Mamadyshsky, Zelenodolsky districts), Eastern Zakamye (Almetyevsky, Bugulminsky districts), Predvolzhye regions (Verkhneuslonsky district) of the Republic of Tatarstan and the Kazan city, the range of heavy metals natural concentrations in the herbaceous vegetation was determined. It has been established that the heavy metals content in herbaceous plants of the Republic of Tatarstan does not exceed the world average clarke. Separate local biogeochemical specializations of plants determined by the natural geochemical background of the region have been established. Wild plants species in the Zelenodolsky district were identified with Pb and Cd content exceeds the established standards.