Regional Enteritis: Associated Visceral Changes

Prevalence of Pancreatic Insufficiency in Inflammatory Bowel Diseases. Assessment by Fecal Elastase-1

“…Studies focusing on morphological and pathological features of idiopathic pancreatitis associated with IBD have found frequent and different macroscopic and microscopic abnormalities. Autopsy studies have revealed pancreatic lesions in up to 53% of UC patients and in 38% of CD patients, none of whom had previous clinical evidence of pancreatic disease [20,21]. The presence of pancreatic lesions in IBD patients has also been reported by Barthet et al who showed that chronic pancreatitis associated with UC differed from that observed in CD due to the more frequent presence of pancreatic duct stenosis [15].…”

“…The existence of different forms of chronic pancreatitis in IBD has already been described [20][21][22]. Studies focusing on morphological and pathological features of idiopathic pancreatitis associated with IBD have found frequent and different macroscopic and microscopic abnormalities.…”

Abnormal pancreatic imaging in Crohn?s disease: prevalence and clinical features

“…These two studies investigated only individuals with subjective symptoms, such as pain in the upper abdominal region. In 1956, Chapin et al 21 conducted an autopsy study of 39 patients who had CD and found fibrosis of the pancreatic lobules and the stroma in 15 (38%). It should be noted, however, that these reports included cases associated with other conditions, such as systemic amyloidosis.…”

Tests of pancreatic exocrine function – Clinical significance in pancreatic and non-pancreatic disorders

“…In ulcerative colitis a pathologic secretin test was present in about half of the patients and PABA test was reduced in 22% [80,83]. Pancreatic duct abnormalities suggesting chronic pancreatitis were detectable in 8% of patients with IBD, a high incidence of pancreatic fibrosis was also observed in autopsy studies [83,84].…”