Recently, quite a lot of attention has been paid to the issues of increasing the infrastructural provision of the regions of the Russian Federation. This is primarily due to the fact that overcoming infrastructural constraints is one of the ways to achieve the goal of sustainable regional development. The article discusses the issues of infrastructural security of Russian regions as one of the factors of their sustainable socio-economic and spatial development. Based on the indicators of the availability of infrastructure facilities, the degree of arrangement of regions with infrastructure facilities was studied and the features of infrastructure provision of individual regions were identified. The differentiation of the regions of the Russian Federation by the level of their infrastructural provision has been investigated. The use of the research results will make it possible to more reasonably approach the determination of the main directions for increasing the infrastructural provision of individual regions of Russia.