The Neoproterozoic–Early Devonian(?) northeast Brooks Range basinal succession of northern Alaska and Yukon represents a peri-Laurentian deep-marine carbonate and siliciclastic succession within the composite Arctic Alaska–Chukotka microplate. The basal Firth River Group consists of a mixed siliciclastic and carbonate succession that is divided into the informal Redwacke Creek, Malcolm River, and Fish Creek formations. New U-Pb detrital zircon geochronology and δ13Ccarb and 87Sr/86Sr isotopic data from these strata, in combination with previously reported and new trace fossil discoveries, suggest the Firth River Group is Cryogenian(?)–middle(?) Cambrian in age. These strata interfinger with or are depositionally overlain by the siliciclastic-dominated lower Cambrian–Middle Ordovician(?) Neruokpuk and Leffingwell (new name) formations, which potentially record a distal expression of Cambrian extension and condensed passive margin sedimentation along the northern margin of Laurentia. All of these units are unconformably overlain by the synorogenic Clarence River Group, which is divided into the informal Aichilik and Buckland Hills formations. New U-Pb detrital zircon geochronology and previous macrofossil collections suggest the Clarence River Group is Late Ordovician-Early Devonian(?) in age. Here, we present new sedimentological observations, stratigraphic subdivisions, detrital zircon U-Pb geochronology and Lu-Hf isotope geochemistry, detrital muscovite 40Ar/39Ar geochronology, and carbonate δ13Ccarb and 87Sr/86Sr isotope geochemistry from the basinal succession that revise previous tectono-stratigraphic models for this part of Arctic Alaska and support correlations with age-equivalent strata in the Franklinian basin of the Canadian Arctic Islands and Greenland.