1997
DOI: 10.1016/s0741-5214(97)70101-0
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Regression of proximal deep venous thrombosis is associated with fibrinolytic enhancement

Abstract: Regression of acute DVT begins early and continues for at least 9 months. It is accompanied by significant enhancement of the endogenous fibrinolysis, which appears to be primarily mediated by increased tPA activity. Patients who have thrombus propagation in spite of standard antithrombotic therapy may have failure of activation of endogenous fibrinolysis.

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Cited by 67 publications
(59 citation statements)
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“…It was reported that recanalization occurred in 44% of patients by 7 days after the onset of DVT and in 100% by 90 days [13] or that recanalization was observed in 87% of patients within 6 weeks after complete venous occlusion by thrombosis [14]. In the present patient, ultrasonography demonstrated recanalization after 52 days owing to continuation of anticoagulation therapy despite gastrointestinal bleeding.…”
Section: Discussionsupporting
confidence: 45%
“…It was reported that recanalization occurred in 44% of patients by 7 days after the onset of DVT and in 100% by 90 days [13] or that recanalization was observed in 87% of patients within 6 weeks after complete venous occlusion by thrombosis [14]. In the present patient, ultrasonography demonstrated recanalization after 52 days owing to continuation of anticoagulation therapy despite gastrointestinal bleeding.…”
Section: Discussionsupporting
confidence: 45%
“…It appears to be primarily mediated by enhancement of the endogenous fibrinolytic system, and increased tissue plasminogen activator (tPA) activity is reported [12].…”
Section: Introductionmentioning
confidence: 99%
“…DVT not related to multiple sheath placement has been reported to be able to remodel, progress, or regress. 14,15) Therefore, we hypothesized that DVT after short-term multiple sheath placement in a single femoral vein may develop early remodeling with benign outcomes.…”
mentioning
confidence: 99%