Regular MDMA use is associated with decreased risk of drug injection among street-involved youth who use illicit drugs

Abstract

After accounting for socio-demographic factors and polysubstance use, periods of reported regular MDMA use were negatively associated with reported injection drug use among this cohort. These findings suggest that, unlike the use of most other non-injection drugs, illicit MDMA use does not appear to promote injection drug use but rather is associated with a reduced likelihood of injection drug use.

Association between Participation in Counseling and Retention in a Buprenorphine-Assisted Treatment Program for People Experiencing Homelessness with Opioid Use Disorder

“…This study contributes to the limited evidence about the use of MDMA among people experiencing homelessness. Among youth in Vancouver, Canada, regular MDMA use reduced intravenous drug use (Gaddis et al, 2018) [33]. Future studies should collect and analyze urine toxicology screens to determine whether MDMA was used alone or in conjunction with other drugs.…”