Regulated cell death in cyanobacteria: Evidences, classification, and significances

Li, Jia‐Da; Song, Lirong; Li, Jie

doi:10.1016/b978-0-323-96106-6.00004-6

Cited by 3 publications

(1 citation statement)

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“…When we had already submitted our manuscript, we came upon the interesting recent publication of Li and co-authors (2022) proposing to subdivide RCD cell types in cyanobacteria based on the involvement of caspase homologs [201]. In our opinion, the proteolytic system in the unicellular cyanobacteria involved in the highly specific proteolysis and a multi-step repair of the thylakoid complexes with de novo synthesized copies may go far beyond caspase family homologs [202,203].…”

Section: Methods To Study Rcd In Cyanobacteriamentioning

confidence: 99%

To Die or Not to Die—Regulated Cell Death and Survival in Cyanobacteria

et al. 2022

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Regulated cell death (RCD) is central to the development, integrity, and functionality of multicellular organisms. In the last decade, evidence has accumulated that RCD is a universal phenomenon in all life domains. Cyanobacteria are of specific interest due to their importance in aquatic and terrestrial habitats and their role as primary producers in global nutrient cycling. Current knowledge on cyanobacterial RCD is based mainly on biochemical and morphological observations, often by methods directly transferred from vertebrate research and with limited understanding of the molecular genetic basis. However, the metabolism of different cyanobacteria groups relies on photosynthesis and nitrogen fixation, whereas mitochondria are the central executioner of cell death in vertebrates. Moreover, cyanobacteria chosen as biological models in RCD studies are mainly colonial or filamentous multicellular organisms. On the other hand, unicellular cyanobacteria have regulated programs of cellular survival (RCS) such as chlorosis and post-chlorosis resuscitation. The co-existence of different genetically regulated programs in cyanobacterial populations may have been a top engine in life diversification. Development of cyanobacteria-specific methods for identification and characterization of RCD and wider use of single-cell analysis combined with intelligent image-based cell sorting and metagenomics would shed more light on the underlying molecular mechanisms and help us to address the complex colonial interactions during these events. In this review, we focus on the functional implications of RCD in cyanobacterial communities.

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Section: Methods To Study Rcd In Cyanobacteriamentioning

confidence: 99%