2020
DOI: 10.3390/medicina56040165
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Regulation and Clinical Implication of Arginine Vasopressin in Patients with Severe Aortic Stenosis Referred to Trans-Catheter Aortic Valve Implantation

Abstract: Background and objectives: Plasma arginine vasopressin (P-AVP) is regulated by the non-osmotic pathway in patients with heart failure (HF) and reduced ejection fraction. However, the regulation of P-AVP in patients with severe aortic stenosis (AS) remains unknown. Materials and Methods: Consecutive patients with severe AS who received trans-catheter aortic valve implantation (TAVI) between Apr 2016 and Apr 2019 were enrolled in this prospective study. Clinical data including P-AVP were obtained just before TAV… Show more

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“…Second, our team could not demonstrate the implication of peri-procedural plasma arginine vasopressin level on clinical outcomes following trans-catheter aortic valve replacement, probably due to relatively maintained periprocedural hemodynamics in most patients [3]. Urine aquaporin-2 level might be useful particularly for the patients with relatively deteriorated hemodynamics including lowflow low-gradient aortic valve stenosis or decompensated heart failure.…”
Section: To the Editormentioning
confidence: 89%
“…Second, our team could not demonstrate the implication of peri-procedural plasma arginine vasopressin level on clinical outcomes following trans-catheter aortic valve replacement, probably due to relatively maintained periprocedural hemodynamics in most patients [3]. Urine aquaporin-2 level might be useful particularly for the patients with relatively deteriorated hemodynamics including lowflow low-gradient aortic valve stenosis or decompensated heart failure.…”
Section: To the Editormentioning
confidence: 89%