Regulation of Rhesus glycoprotein-related genes in large-scale loach Paramisgurnus dabryanus during ammonia loading

Huang, Mei; Shang, Ze-Hao; Wu, Meng-Xiao; Zhang, Lin-Jiang; Zhang, Yun-Long

doi:10.1016/j.ecoenv.2022.114077

Cited by 3 publications

(1 citation statement)

References 63 publications

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“…Additionally, acidifiers are effective in increasing the secretion of mucins in the intestine [ 1 , 11 ], which, in addition to maintaining the health of digestive cells from scratches caused by feed, can increase the washing of pathogenic bacteria out of the digestive system of fish [ 12 ]. Organic acids are effective in reducing oxidative stress and increasing antioxidant capacity, which improves fish health and welfare [ 13 , 14 , 15 ]. In addition, by stimulating the immune system of fish, acidifiers increase the expression of some immune genes such as lysozyme ( lys ), interleukin-1 beta ( il1b ), tumor necrosis factor-alpha ( tnfa ), and defensin ( def ) play a role in fish resistance to diseases [ 5 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Dietary Lactic Acid Supplementation on the Activity of Digestive and Antioxidant Enzymes, Gene Expressions, and Bacterial Communities in the Intestine of Common Carp, Cyprinus carpio

Hoseini,

Yousefi,

Afzali-Kordmahalleh

et al. 2023

Animals

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The present study investigated the effects of dietary lactic acid (LA) supplementation on the growth performance, intestinal digestive/antioxidant enzymes’ activities, gene expression, and bacterial communities in common carp, Cyprinus carpio. Four diets were formulated to contain 0 g/kg LA (control), at 2.5 g/kg LA (2.5LAC), 5 g/kg LA (5LAC), and 10 g/kg LA (10LAC) and offered to the fish over a period of 56 days. The results showed that dietary 5 g/kg LA supplementation improved growth performance and feed efficiency in the fish. All LA treatments exhibited significant elevations in the intestinal trypsin and chymotrypsin activities, whereas the intestinal lipase, amylase, and alkaline phosphatase activities exhibited significant elevations in the 5LAC and 10LAC treatments. All LA treatments exhibited significant elevations in the intestinal heat shock protein 70, tumor necrosis factor-alpha, interleukin-1 beta, and defensin gene expressions, and the highest expression was observed in the 5LAC treatment. Additionally, dietary LA treatment significantly increased the lysozyme expression and Lactobacillus sp. population in the intestine of the fish, and the highest values were observed in the 5LAC and 10LAC treatments. Aeromonas sp. and Vibrio sp. populations decreased in the LA treatments, and the lowest Aeromonas sp. population was observed in the 10LAC treatment. The intestinal mucin2 and mucin5 expressions, and the hepatic reduced glutathione content, significantly increased, whereas hepatic glutathione peroxidase, glutathione reductase, and malondialdehyde significantly decreased in the 5LAC and 10LAC treatments. In conclusion, dietary 5 g/kg LA is recommended for common carp feeding to improve growth rate, antioxidant capacity, and intestinal health.

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