Maxillary jaw abnormalities can be traumatic, acquired, congenital, developmental, or surgical, and they can have an impact on the mouth cavity and nearby anatomical tissues. If the soft palate and/or hard palate are lost whole or partially, the remaining tissues will have an inadequate structure or will no longer function as they once did. Defects can lead to nasal reflux during deglutition and influence speech production by affecting articulation and airflow. This study aims to explore postoperative oroantral or oral-nasal communication for patients who underwent partial maxillectomy and received prosthetic rehabilitation. The complete denture was fabricated with an extension into the defect. As a result, this permanent prosthesis improved the patient's masticatory function, speech clarity, and general quality of life.