Musculoskeletal disorders (MSDs) are soft tissue injuries that occur gradually over time and affect the muscles, tendons, ligaments, joints and nerves. These conditions develop when one or more of these tissues are used for a long period of time without adequate rest. The common MSDs encompasses low backache (LBA) and different types of arthritis, carpal tunnel syndrome etc. LBA is a common problem and the highest prevalence is seen in patients aged 45 to 65 years. Approximately 60-80 % of the world's population experience back pain at some time in their lives. Osteoarthritis (OA) is a major health problem in terms of its prevalence, associated disability and effect on the quality of life. It is the most common form of arthritis worldwide and the leading cause of mobility related disability in the elderly. The best way to prevent MSDs is to educate the people about risk factors and preventive strategies. The present study was planned with an objective to know the prevalence of MSDs and to determine the ratio of diseases in respect of Mizaj (Temperament) of the patients attending Govt. Unani Hospital Shalteng, Srinagar and AYUSH Centres in Kashmir, India. The study was an observational multi-centric cross-sectional hospital based survey. A total of 15529 patients irrespective of age and sex, attending the out-patients departments of these centres were included in the study. A pre-tested semi-structured questionnaire which was based on the demographic profile and risk factors of MSDs was administered to collect the relevant data. The results showed that overall prevalence of MSDs was 2.16 %. The mean age of patients was 42 years. The prevalent morbidities in patients were LBA (33.33 %), OA (25.89 %), Cervical spondylosis (13.69 %), PIVDP (11.01 %), Rheumatoid arthritis (4-46 %), Lumbar spondylosis (4.16 %), Frozen shoulder 1.78 %), Carpal Tunnel syndrome (1.48 %), Osteoporosis (1.19 %), Gout, Kyphoscolosis, Tennis elbow and Sciatica (0.59 %) each and Migratory arthritis and Ganglion (0.29 %) each. The prevalence was highest in patients having Balgami (phlegmatic) temperament.