1999
DOI: 10.1097/00003643-199908000-00004
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Relation between bispectral index and plasma catecholamines after oral diazepam premedication

Abstract: 75 mg in group D(+), and with roxatidine 75 mg only in group D(−) 90 min before arrival in the operating The efficacy of anaesthetic premedication has been theatre. After patients arrived in the operating theatre, assessed using sedative scores or a visual analogue the bispectral index monitor was applied. Venous scale. However, in both it may be difficult to exclude blood samples (6 mL) were collected in the case of evaluators' subjectivity or a placebo effect. Plasma patients in group D(+) for the measuremen… Show more

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Cited by 21 publications
(4 citation statements)
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“…This would avoid the need for sedative premedication with its associated side-effects. BIS has been shown to correlate with clinically assessed sedation levels and is useful for differentiating adequate from inadequate sedation [13][14][15].…”
Section: Discussionmentioning
confidence: 99%
“…This would avoid the need for sedative premedication with its associated side-effects. BIS has been shown to correlate with clinically assessed sedation levels and is useful for differentiating adequate from inadequate sedation [13][14][15].…”
Section: Discussionmentioning
confidence: 99%
“…These results suggested that SGB can induce a sedative effect in humans. Also, these results can be explained by the reduction of NE levels in the brain 70 . The analgesic mechanism of PRF is not very clear, but temperature changes are not responsible for pain relief.…”
Section: Analgesic Mechanisms Of Sgimentioning
confidence: 99%
“…den Sedierungsgrad quantifiziert. Für den bispektralen Index (BIS) konnte ebenfalls gezeigt werden, dass eine relativ einfache und genaue Abschätzung des Sedierungsgrades möglich ist sowie BIS-Werte mit Plasmaspiegeln von Stresshormonen und Katecholaminen nach oraler Applikation von Benzodiazepinen korrelieren [11,12] …”
Section: Hintergrundunclassified
“…Solange aber verschiedene Studien inkonsistente Zusammenhänge zwischen BIS-Werten und einem adäquaten Sedierungsgrad aufzeigen[25] und BISWerte auch von der Patiententemperatur sowie der elektromyographischen Aktivität beeinflusst werden[12,26], bleibt die Wertigkeit des BIS-Monitors zur Beurteilung einer angemessenen präoperativen Sedierungstiefe kontrovers. Einige Limitationen der Studie sollen im Folgenden erwähnt werden.…”
unclassified