Relation Between Hospital Intra-Aortic Balloon Counterpulsation Volume and Mortality in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Chen, Edmond W.; Canto, John G.; Parsons, Lori; Peterson, Eric D.; Littrell, Katherine A.; Every, Nathan R.; Gibson, C. Michael; Hochman, Judith S.; Ohman, E. Magnus; Cheeks, Morris; Barron, Hal V.

doi:10.1161/01.cir.0000085068.59734.e4

Cited by 121 publications

(36 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Th ree studies included all ICU admissions. 16,18,19 Seven clinical conditions were covered: respiratory diagnoses including mechanical ventilation, acute respiratory failure, and pneumonia (13 studies) 15,16,[20][21][22][23][24][25][26][27][28][29][30] ; cardiovascular diagnoses including cardiac arrest and cardiogenic shock (eight studies) [31][32][33][34][35][36][37][38] ; sepsis (six studies) [39][40][41][42][43][44] ; neurologic diagnoses (three studies) 15,45,46 ; hepato-GI diagnoses (three studies) 15,47,48 ; renal diagnoses (three studies) 17,49 ; and postoperative conditions including pancreatectomy, hepatectomy, esophagectomy, major vascular surgery (seven studies). [50][51][52][53][54][55][56] The majority of studies (n 5 24, 52%) used clinical databases rather than administrative databases.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Th ese diagnoses shared the characteristic of being associated with the highest mortality rates within their diagnosis category. Figure 3 shows the meta-analyses of adjusted ORs comparing the lowest-volume group with the highestvolume group in seven conditions, aft er exclusion of eight studies with the majority of data from before 2001 (studies of Durairaj et al, 15 Needham et al, 27 Chen et al, 33 Cross et al, 45 Dimick et al, 50 Kuo et al 55 ). Th e volumeoutcome association remained unchanged aft er exclusion of these studies.…”

Section: Summary Of Findings Of Included Studiesmentioning

confidence: 99%

See 1 more Smart Citation

The Volume-Outcome Relationship in Critical Care

Nguyen

Wallace

Yordanov

et al. 2015

Chest

119

View full text Add to dashboard Cite

, MEDLINE and EMBASE were searched for studies assessing the relationship between admission volume and clinical outcomes in critical illness. Bibliographies were reviewed to identify other articles of interest, and experts were contacted about missing or unpublished studies. Of 127 studies reviewed, 46 met inclusion criteria, covering seven clinical conditions. Two investigators independently reviewed each article using a standardized form to abstract information on key study characteristics and results. 05-8.30]) were more likely to benefi t from admission to higher-volume centers compared with lower-volume centers. Studies that controlled for ICU or hospital organizational factors were less likely to fi nd a signifi cant volume-outcome relationship than studies that did not control for these factors. CONCLUSIONS:Critically ill patients generally benefi t from care in high-volume centers, with more substantial benefi ts in selected high-risk conditions. Th is relationship may in part be mediated by specifi c ICU and hospital organizational factors.

show abstract

Section: Study Characteristicsmentioning

confidence: 99%

Section: Summary Of Findings Of Included Studiesmentioning

confidence: 99%

The Volume-Outcome Relationship in Critical Care

Nguyen

Wallace

Yordanov

et al. 2015

Chest

119

View full text Add to dashboard Cite

show abstract

“…In the large National Registry of Myocardial Infarction, IABP use was independently associated with survival at centers with higher rates of IABP use, whether PCI, fibrinolytic therapy, or no reperfusion had been used 53 ; however, no completed trials demonstrate benefit. Complications associated with IABP are less common in the modern era; in the largest series, the overall and major complication rates were 7.2% and 2.8%, respectively.…”

Section: Pharmacological Treatmentmentioning

confidence: 99%

Cardiogenic Shock

2008

Self Cite

View full text Add to dashboard Cite

ardiogenic shock (CS) occurs in Ϸ5% to 8% of patients hospitalized with ST-elevation myocardial infarction (STEMI). Recent research has suggested that the peripheral vasculature and neurohormonal and cytokine systems play a role in the pathogenesis and persistence of CS. Early revascularization for CS improves survival substantially. New mechanical approaches to treatment are available, and clinical trials are feasible even in this high-risk population. Most importantly, hospital survivors have an excellent chance for long-term survival with good quality of life. This review will outline the causes, pathophysiology, and treatment of CS with a focus on CS complicating myocardial infarction (MI.) The case will be made for viewing CS as a serious disorder with a high early death rate, but one that is treatable and that, if approached aggressively, can result in full recovery. The diagnosis is usually made with the help of pulmonary artery (PA) catheterization; however, Doppler echocardiography may also be used to confirm elevation of LV filling pressures. 1 Hypoperfusion may be manifest clinically by cool extremities, decreased urine output, and/or alteration in mental status. Hemodynamic abnormalities form a spectrum that ranges from mild hypoperfusion to profound shock, and the short-term outcome is directly related to the severity of hemodynamic derangement. MI with LV failure remains the most common cause of CS. It is critical to exclude complicating factors that may cause shock in MI patients. Chief among these are the mechanical complications: ventricular septal rupture, contained free wall rupture, and papillary muscle rupture. Mechanical complications must be strongly suspected in patients with CS complicating nonanterior MI, particularly a first MI. Echocardiography is the technique of choice to rule out these entities and should be performed early unless the diagnosis is extensive anterior MI and the patient is undergoing prompt percutaneous coronary intervention (PCI). In addition, the detection of valvular disease before angiography may alter the revascularization approach. Diagnosis and CausesHemorrhage, infection, and/or bowel ischemia may contribute to shock in the setting of MI. As with mechanical complications, a high index of suspicion is required to make these diagnoses in MI patients, and survival may depend on timely recognition and treatment.Any cause of acute, severe LV or RV dysfunction may lead to CS. Acute myopericarditis, tako-tsubo cardiomyopathy, and hypertrophic cardiomyopathy may all present with ST elevation, release of cardiac markers, and shock in the absence of significant coronary artery disease. Stress-induced cardiomyopathy, also known as apical ballooning or takotsubo cardiomyopathy, is a syndrome of acute LV dysfunction after emotional or respiratory distress that leads to CS in 4.2% of cases. 2 Acute valvular regurgitation, typically caused by endocarditis or chordal rupture due to trauma or degenerative disease, may also cause CS. Aortic dissection may lead to CS via acute,...

show abstract

“…[13][14][15] In a sub-analysis of the American National Registry of Myocardial Infarction 2 (NRMI-2), 16 the mortality rate from AMI complicated by cardiogenic shock, even in hospitals with extensive use of intra-aortic balloon, was 50.6%,versus 65.4% in hospitals with lower rates of use of this circulatory support device (P < 0.001).…”

Section: Discussionmentioning

confidence: 99%

Evolução hospitalar de pacientes com choque cardiogênico por infarto agudo do miocárdio com supradesnivelamento do segmento ST

Filho¹,

Conejo²,

Santos³

et al. 2013

Rev. Bras. Cardiol. Invasiva

View full text Add to dashboard Cite

Background: Cardiogenic shock is a clinical condition of inadequate tissue perfusion due to cardiac dysfunction. The most common etiology is ST-segment elevation myocardial infarction (STEMI) leading to left ventricular failure, but it may also be caused by mechanical complications such as acute mitral regurgitation, ventricular septal rupture or rupture of the left ventricular free wall. Despite therapeutic advances, mortality rates remain high. Methods: Retrospective, observational, single-center study, including consecutive patients admitted with a diagnosis of STEMI and cardiogenic shock treated by percutaneous coronary intervention (PCI) at a tertiary hospital specialized in cardiology. The primary objective was to evaluate in-hospital clinical outcomes. Results: A total of 78 patients were included, most of them were male (67.9%), mean age was 67.5 ± 13,4 years and 41.0% were diabetic. Primary PCI was performed in 46.2% of the patients, rescue PCI in 25.6% and elective PCI in 28.2% of the cases. The most frequently involved arteries were the left anterior descending artery and the right coronary artery, with 44.9% each. Intra-aortic balloon pump was used in 32.1% of cases and glycoprotein IIb/ IIIa inhibitors in 30.8% of the cases. The incidence of acute renal failure was 61.5%. The need for reintervention was observed in 9.0% and the rate of acute/subacute thrombosis was 3.8%. Death due to cardiogenic shock was observed in 46.2%. Conclusions: Cardiogenic shock remains a frequent and serious condition with almost 50% of in-hospital mortality despite the therapeutic advances.

show abstract

Relation Between Hospital Intra-Aortic Balloon Counterpulsation Volume and Mortality in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Cited by 121 publications

References 34 publications

The Volume-Outcome Relationship in Critical Care

The Volume-Outcome Relationship in Critical Care

Cardiogenic Shock

Evolução hospitalar de pacientes com choque cardiogênico por infarto agudo do miocárdio com supradesnivelamento do segmento ST

Contact Info

Product

Resources

About