Plasmaspheric hiss waves are mostly structureless, low frequency (100 Hz to few kHz) broadband whistler mode electromagnetic emissions confined inside the high-density plasmasphere and duskside plasmaspheric Abstract We present, for the first time, a plasmaspheric hiss event observed by the Van Allen probes in response to two successive interplanetary (IP) shocks occurring within an interval of ∼2 h on December 19, 2015. The first shock arrived at 16:16 UT and caused disappearance of hiss for ∼30 min. Combined effect of plasmapause crossing, significant Landau damping by suprathermal electrons and their gradual removal by magnetospheric compression led to the disappearance of hiss. Calculation of electron phase space density and linear wave growth rates showed that the shock did not change the growth rate of whistler waves within the core frequency range of plasmaspheric hiss (0.1-0.5 kHz) during this interval making conditions unfavorable for the generation of hiss. The recovery began at ∼16:45 UT which is attributed to an enhancement in local plasma instability initiated by the first shock-induced substorm and additional possible contribution from chorus waves. This time, the wave growth rate peaked within the core frequency range (∼350 Hz). The second shock arrived at 18:02 UT and generated patchy hiss persisting up to ∼19:00 UT. It is shown that an enhanced growth rate and additional contribution from shock-induced poloidal Pc5 mode (periodicity ∼240 s) ultralow frequency (ULF) waves resulted in the excitation of hiss waves during this period. The hiss wave amplitudes were found to be additionally modulated by background plasma density and fluctuating plasmapause location. The investigation highlights the important roles of IP shocks, substorms, ULF waves, and background plasma density in the variability of plasmaspheric hiss.Plain Language Summary Plasmaspheric hiss waves are whistler-mode, low frequency electromagnetic emissions found inside the dense plasmasphere and duskside plasmaspheric plumes. These waves play important role in controlling radiation belt dynamics by efficiently scattering electrons leading to their precipitation into the atmosphere. Therefore, understanding their variability is an important topic in radiation belt studies. Earlier studies on plasmaspheric hiss waves showed their intensification as well as disappearance following a single interplanetary (IP) shock impact. In this study, we provide the first direct observational evidence of plasmaspheric hiss variability in response to two consecutive IP shocks hitting the magnetosphere within an interval of ∼2 h based on unique observations by the twin Van Allen probes. Based on these observations and supported by detailed linear wave growth rate and phase space density analyses, it is shown that substorms triggered by both the IP shocks and ultralow frequency waves generated after the second shock modulated the plasmaspheric hiss wave intensities in a significant manner. The amplitudes of the hiss waves are also found to be modulated b...