Relation of Warrick Score and Polysomnographic Parameters in Patients with Interstitial Lung Disease

Kavas, Murat; Şahin, Murat; Aras, Gülfidan; Afşar, Gülgün Çetintaş; Tezel, Yelda

doi:10.12659/msm.914905

Cited by 10 publications

(10 citation statements)

References 21 publications

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“…Subgroup analyses were performed to evaluate sources of heterogeneity in the prevalence estimates between studies. The results revealed the prevalence to be higher as 76% (95% CI: 68-83%; I 2 = 69.2%) in the 13 studies enrolling IPF patients [10,[12][13][14][18][19][20][21][22][23][24][25][26] (Fig 2B), whereas in 4 studies including patients with connective tissue associated-ILD or sarcoidosis [20,21,25,26], the pooled prevalence of OSA was much lower (60%, 95% CI: 49-70%; I 2 = 0%), suggesting that the prevalence differed according to the type of DPLDs. Moreover, the prevalence of comorbid OSA in healthy controls and chronic obstructive pulmonary disease (COPD) were examined in two studies, and were found to be less frequent than in IPF (AHI 1.7 ± 1.0 vs 11.6 ± 7.2 [21]; prevalence 44% vs 62% [27]).…”

Section: Characteristics Of Eligible Studiesmentioning

confidence: 94%

“…Quality assessment for each study is summarized in S1 Table. Prevalence of OSA in DPLDs Overall, the pooled prevalence of OSA among DPLDs was 72% (95% CI: 65-79%; I 2 = 75.4%), ranging from 45 to 90% (Fig 2A). Based on 12 studies including 546 patients, which reported severity of OSA [10,12,13,[18][19][20][21][22][23][24][25][26], moderate-severe OSA was observed in 40% patients (95% CI: 28-52%; I 2 = 90.8%), ranging from 8 to 68%, and the pooled prevalence of mild OSA was equally high as 36% (95% CI: 23-48%; I 2 = 91.5%), ranging from 6 to 67%.…”

Section: Characteristics Of Eligible Studiesmentioning

confidence: 99%

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Prevalence and impact of comorbid obstructive sleep apnoea in diffuse parenchymal lung diseases

Wang

Liu

et al. 2021

PLoS ONE

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Objective Obstructive sleep apnea (OSA) are increasingly recognized as important features in diffuse parenchymal lung diseases (DPLDs) with differed prevalence and impact reported. The aim of this study is to systematically review the prevalence of comorbid OSA and characterize its impact on clinical and outcome measurements in adults with DPLDs. Methods Publications addressing the prevalence of OSA in DPLDs and its impacts on DPLDs were selected from electronic databases. A random-effect model was used to estimate the pooled prevalence of OSA. Odds ratios (ORs) or mean differences (MDs) were used to assess the associations of OSA with clinical and outcome measurements. Heterogeneity was quantified by I2 with 95% confidence interval (95% CI). Results 4 studies comprising 643 participants were included. Overall, the pooled prevalence of OSA among DPLDs was 72% (95% CI: 65–79%; I2 = 75.4%). Moderate-severe OSA was observed in 40% patients (95% CI: 28–52%; I2 = 90.8%). The prevalence was higher as 76% in idiopathic pulmonary fibrosis (IPF) patients than in connective tissue associated-ILD or sarcoidosis (60%). Although oxygen desaturation during sleep was greater in OSA group compared with non-OSA patients, there was no difference in lung function or systematic comorbidities between the two groups. The associations between OSA and the mortality or disease progression of DPLDs were also systematically reviewed. Conclusion In conclusion, OSA is a common comorbidity in DPLD patients, affecting approximately three in four patients, which may exacerbate the nocturnal desaturation and have negative influence on the outcomes. Larger studies with more homogeneous samples are warranted.

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Section: Characteristics Of Eligible Studiesmentioning

confidence: 94%

Section: Characteristics Of Eligible Studiesmentioning

confidence: 99%

Prevalence and impact of comorbid obstructive sleep apnoea in diffuse parenchymal lung diseases

Wang

Liu

et al. 2021

PLoS ONE

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“…Each square represents the effect estimate of a single publication, while horizontal lines represent a 95% confidential interval. The size of squares is proportional to the weight of each paper in the meta-analysis [ 5 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 ]. Exact data are available as Supplementary Table S3 .…”

Section: Figurementioning

confidence: 99%

The Association between Idiopathic Pulmonary Fibrosis and Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis

Karuga

Kaczmarski

Szmyd

et al. 2022

JCM

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The prevalence of obstructive sleep apnea (OSA) has greatly increased in recent years. Recent data suggest that severe and moderate forms of OSA affect between 6 and 17% of adults in the general population. Many papers are reporting the significantly increased prevalence of OSA in patients suffering from fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). Therefore, we performed a systematic review and meta-analysis regarding the dependency between IPF and OSA. Due to the lack of papers focusing on IPF among OSA patients, we focused on the prevalence of OSA among IPF patients. In the search strategy, a total of 684 abstracts were identified, 496 after the removal of duplicates. After the screening of titles and abstracts, 31 studies were qualified for further full-text analysis for eligibility criteria. The final analysis was performed on 614 IPF patients from 18 studies, which met inclusion criteria. There were 469 (76.38%) IPF patients with OSA and 145 (23.62%) without. The mean age varied from 60.9 ± 8.1 up to 70.3 ± 7.9. The obtained prevalence was 76.4 (95% CI: 72.9–79.7) and 75.7 (95% CI: 70.1–80.9) for fixed and random effects, respectively. The median prevalence of OSA among non-IPF patients for all the ethnics groups included in this study was 16,4% (IQR: 3.4%–26.8%). The study provides strong evidence for the increased prevalence of OSA in IPF patients when comparing with the general OSA prevalence.

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“…In the present study, 46% had mild, 44% had moderate and 10% had severe disease according to Warrick score. Sarac et al [15] reported a lower Warrick score, and their patients had mild to moderate disease. In Farag et al [16] revealed no association between B-lines scores and different grades of disease severity discovered by HRCT.…”

mentioning

confidence: 94%

“…It starts by alveolitis and reaching up to fibrosis. The score vary between 0 [minimum] to 30 [maximum] and higher score indicates severe disease, with high degree of change on radiological study [15] .…”

mentioning

confidence: 99%

Comparison Study between Chest Ultrasonography and High Resolution CT in Diagnosis and Assessment of Interstitial Lung Diseases

Elmansy

Abdel-Aziz

Shaqueer

et al. 2020

International Journal of Medical Arts

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Background: Chest high-resolution computed tomography [HRCT] is considered the "gold" standard for radiological diagnosis of interstitial lung disease [ILD]. However, it is not available in all health care facilities and its high cost is a limitation for its wide use. Ultrasound could provide a suitable alternative. Aim of the work: To detect the role of transthoracic lung ultrasonography [LUS] in diagnosis and assessment of ILD and to correlate it with HRCT as a gold-standard diagnostic modality. Methods: This included fifty patients who were admitted with clinical features suggestive of ILD. All were clinically evaluated [by full history and physical examination], submitted to pulmonary functions, arterial blood gases, lung ultrasound and HRCT. Results: The total sum of B-lines was 72.64 ± 39.45 and the total positive chest areas [> 3 B-lines] 6.47 ± 2.35. The most common ultrasound finding was thick pleural line. Finally, there was positive [proportional], moderate, significant correlation between Warrick's score [HRCT] and B-lines distance [LUS]. However, Warrick score correlated negatively with each of six-minute walk test, partial arterial oxygen tension and forced vital capacity. Conclusions: Lung ultrasound as a diagnostic modality for ILD reveled that, it is a useful tool, as there was good correlation between LUS and HRCT. LUS is cheap, accessible and radiation-free diagnostic tool. It could play a stand alone or a complementary role in the diagnosis and monitoring of ILD.

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Relation of Warrick Score and Polysomnographic Parameters in Patients with Interstitial Lung Disease

Cited by 10 publications

References 21 publications

Prevalence and impact of comorbid obstructive sleep apnoea in diffuse parenchymal lung diseases

Prevalence and impact of comorbid obstructive sleep apnoea in diffuse parenchymal lung diseases

The Association between Idiopathic Pulmonary Fibrosis and Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis

Comparison Study between Chest Ultrasonography and High Resolution CT in Diagnosis and Assessment of Interstitial Lung Diseases

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