Relations of Lifestyle Behavior Clusters to Dyslipidemia in China: A Compositional Data Analysis

Abstract

Dyslipidemia is associated with lifestyle behaviors, while several lifestyle behaviors exist collectively among some populaitons. This study aims to identify lifestyle behavior clusters and their relations to dyslipidemia. This cross-sectional study was conducted in Wuhai City, China. Cluster analysis combined with compositional data analysis was conducted, with 24-h time-use on daily activities and dietary patterns as input variables. Multiple logistic regression was conducted to compare dyslipidemia among clusters. A total of 4306 participants were included. A higher prevalence of newly diagnosed dyslipidemia was found among participants in cluster 1 (long sedentary behavior (SB) and the shortest sleep, high-salt and oil diet) /cluster 5 (the longest SB and short sleep), relative to the other clusters in both age groups (<50 years and ≥50 years). In conclusion, unhealthy lifestyle behaviors may exist together among some of the population, suggesting that these people are potential subjects of health education and behavior interventions. Future research should be conducted to investigate the relative significance of specific lifestyle behaviors in relation to dyslipidemia.

Associations of Socioeconomic Status and Healthy Lifestyle With Incidence of Dyslipidemia: A Prospective Chinese Governmental Employee Cohort Study

“…In this study, we found that unhealthy sleep quality was more prevalent among participants of low SES, which was consistent with the previous study ( 50 ). Although we constructed a lifestyle score, including baseline sleep quality in the sensitivity analysis, the results remained similar, suggesting that other unmeasured lifestyles may play a role, such as sedentary behavior ( 17 , 51 ). Existing study shows SES-related health effects of social environments (e.g., isolation and the lack of engagement in social networks) may be even more important than those of physical environments ( 8 ).…”

“…Additionally, lifestyles are mutually connected and limited studies conducted lifestyle score to evaluate its effect on the socioeconomic inequities in dyslipidemia. Based on the literature, both SES (low SES) ( 16 , 17 ) and unhealthy lifestyles (e.g., less physical activity, irrational diet, etc.) ( 18 , 19 ) are associated with the risk of dyslipidemia.…”

Association between healthy lifestyle score and dyslipidemia; a population based study

“…Moreover, a study of 7,586 adults found that heavy smokers had signi cantly lower HDL-C and TC levels than light smokers after quitting smoking [22]. Sedentary behaviors and general and central obesity have also been reported to have a positive relationship with dyslipidemia in various studies [7,8,23].…”

“…Gao et al's study in North China shows that dyslipidemia is negatively correlated with HLS [13]. In a study based on cluster analysis, a higher prevalence of dyslipidemia was reported in a cluster whose population had long-term sedentary behavior, the shortest sleep, and a high salt and oil diet [7]. A study on the Iranian population has shown that the use of statins for dyslipidemia patients is low, and 44.2% of patients who are aware of their dyslipidemia receive statin treatment [14].…”

“…Unhealthy lifestyles including sedentary behavior, short sleep, high salt and oil diet, smoking and obesity have been associated with dyslipidemia [6][7][8][9]. Indeed, scienti c evidence has demonstrated that risk factors such as unhealthy lifestyles, including sedentary behavior, poor diet, smoking, and obesity, are interconnected.…”