Relationship between ABO blood groups and carcinoma of esophagus and cardia in Chaoshan inhabitants of China

Su, Min; Lu, Shuyang; Tian, Dan; Zhao, Haitao; Li, Xiaoyun; Li, Derui; Zheng, Zhichao

doi:10.3748/wjg.7.657

Cited by 11 publications

(13 citation statements)

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“…Numerous studies show that the percentage of ABO and Rh blood types was found to be quite different in different samples of patients [18][19][20][21][22][23][24][25]. According to those findings, we assume that certain connection between predisposition to CDH and frequencies of ABO and Rh blood types exists.…”

Section: Introductionmentioning

confidence: 54%

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Cvjetićanin¹,

Marinković²

2005

Russ J Genet

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Our study of genetic homozygosity degree includes an analysis of the presence, distribution, and individual combination of 20 selected genetically controlled morphophysiological traits in the group of patients ( N = 93) with congenital hip dislocation (CDH) and in control sample consisting of schoolchildren from Belgrade ( N = 200). Assuming that CDH is a genetically controlled disease, we made a hypothesis that an increased homozygosity level, as well as the changed variability among the patients, could be a population-genetic parameter for the prediction of the illness. Taking into consideration our experience, as well as the experience of numerous scientists who studied the nature of the inheritance of mono-and oligogenically controlled qualitative traits, we applied a methodology to estimate the proportion of such homozygously recessive characters (HRC-TEST). This population-genetic study did not only show statistically significant difference of the middle values of genetic homozygosity (CDH: 7.1 ± 0.2; control: 5.2 ± 0.1), but of the differences in the type of distribution too, as well as the differences in the presence of certain individual combinations of such traits. The described methodology can be used in further analyses, with hope that it can be applied as an early prognosis for decreased resistance to different diseases.The frequencies of ABO blood types in the sample of CDH patients were similar to the average value of the Serbian population, while the percentage of blood group A is slightly increased. Comparing frequencies of Rh blood groups, there is no difference between tested samples. HUMAN GENETICS* This text was submitted by the authors in English.

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Section: Introductionmentioning

confidence: 54%

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Cvjetićanin¹,

Marinković²

2005

Russ J Genet

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“…Nanao Island, a relatively isolated island of about 105 km 2 with 70,000 residents, locates in the South China Sea of the Chaoshan littoral region, close to Shantou city. According to history, chorography, and genealogy record, it is generally believed that the ancestors of Nanao residents migrated from central plains of China hundreds even thousand years ago, where the above mentioned high-risk regions for EC locate [6][7][8]. In order to provide an up-to-date perspective on the occurrence of cancer in this particular group of people, we embarked on a study to provide an overview of the cancer frequency and incidence rates from 1995 to 2004.…”

Section: Introductionmentioning

confidence: 99%

Temporal trends of esophageal cancer during 1995–2004 in Nanao Island, an extremely high-risk area in China

et al. 2006

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The purpose of our study was to investigate the temporal malignant tumor incidence rates among the 70,000 residents at the relatively isolated Nanao Island in South China Sea. The data on all malignant tumor cases from Nanao Cancer Registry during 1995-2004 were coded, computerized, and analyzed using the software SPSS10.0. The tumor incident cases, crude incident rate, age-standardized incidence rate, their sex distribution and temporal trend were assessed. A total of 1450 new cancer cases (990 males and 460 females) were identified. The annual average age-standardized incidence rate (ASR) of malignant tumors was 208.18/100,000. The age-standardized incidence rate of the ten leading cancers in both sexes combined per 100,000 population were 74.47 for esophageal cancer (EC), 34.81 for cardiac cancer (CC), 25.66 for liver cancer, 26.01 for lung cancer, 18.52 for stomach cancer, 4.45 for nasopharyngeal cancer, 3.91 for breast cancer, 2.53 for colon/rectum cancer, 2.45 for bladder cancer and 1.92 for pancreatic cancer. These ten types of cancers make up to 93% of all cancer cases, with EC and CC being the most prevalent and making up 52% of the total cases. The incidence rates of esophagus, liver, lung, breast, nasopharyngeal, and colon/rectum cancers showed increasing trends during the period from 1995 to 2004 in Nanao Island. Astounding the EC ASR were 72-150/100,000 among male and 26-64/100,000 among female in Nanao Island during 1995-2004. The EC incidence rate in Nanao population is among the highest across the world, which suggests that there are potential genetic and/or environmental factors affecting this particular population.

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“…The Sezik's study showed that 48% of the patients with HELLP syndrome had a negative blood type O and RH and they were at a greater risk for the syndrome (29). Min Su et al showed that blood group B has a correlation with heart disease in males and cancer in the upper third of the esophagus (30). The study by Engin et al showed that blood group A was more common in patients with pancreatic cancer and the blood group seems to be a protective agent against pancreatic cancer.…”

Section: Discussionmentioning

confidence: 99%

The Relationship Between Blood Group and Colon Cancer in Shiraz Namazi Hospital During 2002 - 2011

Kashfi

Bazrafshan

Kashfi

et al. 2018

Jundishapur J Chronic Dis Care

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Background: Cancer is the second cause of death in the world and the third in Iran. Colorectal cancer is the third fatal cancer in the world. Objectives: Blood group and its RH are among the genetic factors that can be associated with colon cancer. This study was performed with the aim of investigating the relationship between blood group and colon cancer. Methods: This study was undertaken in cases of colon cancer that referred to Namazi hospital from 2002 to 2011. The required data were gathered using a checklist, entered into SPSS software, and analyzed with descriptive statistical methods and Chi-square test. Results:The results showed that the highest frequencies among 223 patients with colon cancer were related to blood group O+ (48.7 percent), RH+ (90.4 percent), male patients (60.4 percent), and married people (72.2 percent). The mean age of the patients was 60.09 ± 16.04. Blood group and colon cancer showed a statistically significant relationship (P < 0.05). Conclusions:The findings showed that there is a statistically significant relationship between blood group and colon cancer. Conducting extensive studies to find risk factors of the disease, particularly the role of genetic factors and disease prevention, in susceptible people is recommended.Keywords: Blood Group, Colon Cancer, Relationship BackgroundCancer is defined as a condition in which some cells begin to multiply in particular conditions out of natural processes (1). In recent years, major causes of death in humans have shifted from infectious diseases towards noncommunicable ones and cancer is known as the third leading cause of death after heart disease and accidents in Iran (2). Today, nearly 7 million cancer deaths occur annually in the world (13 percent of all deaths) and 10.5 million new cases of cancer become malignant. In Iran, according to the state records, 86.6 and 56.1 percent of cancer cases in 2003 and 2004, respectively, occurred in males and 43.3 and 43.9 percent were in females (3). At the beginning of the present century, the major causes of lethal cancers were lung, stomach, liver, colon, breast, and esophagus, in sequence. In 2005, lung, stomach, liver, colon, and breast cancers were responsible for 1.3, 1, 0.66, 0.65, and 0.5 million deaths, respectively (4). The reports of the world health organization in 2000 and 2005 show that stomach, esophagus, and colon cancers were among the six cancers with highest mortality rates (5). Colorectal cancer is the third most common cancer in men and the second most common cancer in women, and more than 1.2 million new cases are diagnosed every year in the world (6). The cause of cancer is not a single disease, but a set of factors (environmental, hereditary, and genetic factors) act together to cause cancer (1). Colon cancer is the most common gastrointestinal cancer and is the second leading cause of death in America and other developed countries (7). Etiology of colon and rectum cancer is unknown like other cancers (8-10). However, it is known today that genetic factors a...

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Relationship between ABO blood groups and carcinoma of esophagus and cardia in Chaoshan inhabitants of China

Abstract: ABO blood group B is associated with the incidence of CC in male individuals and carcinoma in the upper third esophagus. The distribution of ABO blood groups varies in the different geographical and ethnic groups. As a result, proper controls are very important for such studies.

Cited by 11 publications

References 0 publications

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Genetic Variability in the Group of Patients with Congenital Hip Dislocation

Temporal trends of esophageal cancer during 1995–2004 in Nanao Island, an extremely high-risk area in China

The Relationship Between Blood Group and Colon Cancer in Shiraz Namazi Hospital During 2002 - 2011

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