Relationship between adiponectin, glycemic control and blood lipids in diabetic type 2 postmenopausal women with and without complication of ischemic heart disease

Jaleel, Farhan; Jaleel, Anila; Aftab, Jawed; Rahman, Mohammad Masudur

doi:10.1016/j.cca.2006.01.022

Cited by 19 publications

(19 citation statements)

References 15 publications

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“…In this study, diabetic patients showed significantly decreased serum adiponectin levels compared to the controls. Also, serum levels of lipids and lipoproteins (TG, LDL-C, Apo-A1 and Apo-B) were significantly increased but HDL-C was decreased with decreasing adiponectin levels, as reported in previous studies (12)(13)(14). Several studies have also reported a positive correlation between plasma adiponectin and HDL-C levels (15).…”

Section: Discussionsupporting

confidence: 80%

Relationship between adipocytokines and cardiovascular risk factors in patients with type 2 diabetes mellitus

Uslu

Kebapçı

Kara

et al. 2012

Experimental and Therapeutic Medicine

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Abstract. The aim of this study was to explore the relationship between serum profiles of adiponectin, leptin, resistin and visfatin and traditional and non-traditional cardiovascular risk factors in patients with type 2 diabetes mellitus (T2DM). A total of 85 patients with T2DM and 30 non-diabetic controls were enrolled in the study. Levels of adipocytokines (adiponectin, leptin, resistin and visfatin), lipids (total cholesterol, triglycerides), lipoproteins [HDL-cholesterol, LDL-cholesterol, lipoprotein (a)], apolipoproteins (Apo-A1 and Apo-B), non-traditional cardiovascular risk markers [asymmetric dimethylarginine (ADMA), homocysteine] and the inflammatory marker hs-CRP were measured, and anthropometric variables were determined. Serum adiponectin levels were decreased and leptin, resistin and visfatin levels were increased in T2DM patients compared to controls. They were associated with obesity (BMI), insulin resistance (HOMA-IR) and various markers of glucose/lipid profile, inflammation and endothelial dysfunction markers. These results suggest that decreased serum adiponectin and increased leptin, resistin and visfatin levels in T2DM may be novel biochemical risk factors for cardiovascular complications.

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Section: Discussionsupporting

confidence: 80%

Relationship between adipocytokines and cardiovascular risk factors in patients with type 2 diabetes mellitus

Uslu

Kebapçı

Kara

et al. 2012

Experimental and Therapeutic Medicine

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“…It is a member of the adiposecreted proteins termed 'adipocytokines' or 'adipokines' [2][3][4]. Adiponectin has been proposed to exhibit a protective effect against atherosclerosis.…”

Section: Introductionmentioning

confidence: 99%

Serum adiponectin and leptin as predictors of the presence and degree of coronary atherosclerosis

Hasan‐Ali¹,

El-Mottaleb²,

Hamed

et al. 2011

Coronary Artery Disease

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“…Circulating levels of these adipokines become more proatherogenic during menopause 7) , and low serum adiponectin is a risk of CVD in postmenopausal women with diabetes 8) . Hence, this study aimed to investigate whether ESR-1 genotypes might influence circulating levels of these adipokines and inflammatory mediators in postmenopausal women with type 2 diabetes.…”

Section: Introductionmentioning

confidence: 99%

Association of Polymorphism of Estrogen Receptor-.ALPHA. Gene with Circulating Levels of Adiponectin in Postmenopausal Women with Type 2 Diabetes

Yoshihara

Utsunomiya

Gojo

et al. 2009

JAT

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Relationship between adiponectin, glycemic control and blood lipids in diabetic type 2 postmenopausal women with and without complication of ischemic heart disease

Cited by 19 publications

References 15 publications

Relationship between adipocytokines and cardiovascular risk factors in patients with type 2 diabetes mellitus

Relationship between adipocytokines and cardiovascular risk factors in patients with type 2 diabetes mellitus

Serum adiponectin and leptin as predictors of the presence and degree of coronary atherosclerosis

Association of Polymorphism of Estrogen Receptor-.ALPHA. Gene with Circulating Levels of Adiponectin in Postmenopausal Women with Type 2 Diabetes

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