Relationship Between Central Corneal Thickness, Refractive Error, Corneal Curvature, Anterior Chamber Depth and Axial Length

Chen, Mei-Ju; Liu, Yin-Tzu; Tsai, Chia-Chen; Chen, Yen-Cheng; Chou, Chen Kung; Lee, Shu-Mei

doi:10.1016/s1726-4901(09)70038-3

Cited by 100 publications

(99 citation statements)

References 24 publications

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“…The average CCT of this study was smaller than the 563.0 38.0 and 562.8 31.3µm reported for Caucasians by Aghaian et al (2004) and Semes et al (2006). This value was close to that of the Taiwanese Chinese (554.0 29.0µm) (Chen et al, 2009).…”

Section: Discussionsupporting

confidence: 57%

“…The potential for central corneal thickness to significantly impact on the intraocular pressure, including diagnosis and management options of glaucoma, has aroused great interest in its distribution in different populations (Dueker et al, 2007) and races (Hahn et al, 2003;Shimmyo et al, 2003;Aghaian et al, 2004;Kohlhaas et al, 2006;Mercieca et al, 2007;Iyamu and Ituah, 2008;Chen et al, 2009). Several factors affect the central corneal thickness including race, ethnicity, age and gender.…”

Section: Discussionmentioning

confidence: 99%

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The Relationship between Central Corneal Thickness and Intraocular Pressure in Adult Nigerians without Glaucoma

Iyamu¹,

Kio²,

Idu³

et al. 2011

Sierra Leone j. biomed. res.

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The aim of this study was to investigate the relationship between central corneal thickness (CCT) and intraocular pressure (IOP) in a predominantly black population. A total of eighty-five subjects (right eyes) with mean age 44.7 ± 15.1 years consisting of 49 males and 36 females were recruited for this study. The central corneal thickness was measured by ultrasound pachymetry (SW-1000P pachymeter, Tianjin Suowei Electronic Technology, China) and intraocular pressure with Keeler Pulsair EasyEye Non-contact tonometer (Keeler Instruments, USA). The mean CCT for the studied population was 550.0 ± 36.3µm, while the mean IOP was 15.0 ± 2.6mmHg. Although there was a downward trend in the central corneal thickness towards the older age, the association between CCT and age was significant (r=-0.25, p=0.021). However, the association between intraocular pressure and age was not significant (r=0.091, p=0.41). There was no significant association between CCT and IOP (r=0.052, p=0.64). Neither central corneal thickness nor intraocular pressure was influenced by age. There was no significant association between central corneal thickness and intraocular pressure.

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Section: Discussionsupporting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

The Relationship between Central Corneal Thickness and Intraocular Pressure in Adult Nigerians without Glaucoma

Iyamu¹,

Kio²,

Idu³

et al. 2011

Sierra Leone j. biomed. res.

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“…Central corneal thickness is not associated with age, gender, occupation, refractive error, corneal curvature, anterior chamber depth, or axial length [28][29][30]. Hepsen and co-authors found thicker central cornea in patients with PEX than in the control group using the Pentacam imaging system [31].…”

Section: Resultsmentioning

confidence: 98%

Optical low-coherence reflectometry enables preoperative detection of zonular weakness in pseudoexfoliation syndrome

Bosnar¹,

Elabjer²,

Bušić³

et al. 2011

Graefes Arch Clin Exp Ophthalmol

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“…A great number of reports have shown a negative relationship between AL and myopia. In other words, the longer the AL, the severer the myopia [41,42]. Olsen et al [35] found that when considering the contribution of AL, lens power and corneal power together, using multiple linear regression analyses, it can explain up to 96% of the variation of refraction in populations.…”

Section: Axial Lengthmentioning

confidence: 99%

Axial Length of Myopia: A Review of Current Research

Wang

Butterworth²,

Malecaze³

et al. 2010

Ophthalmologica

180

135

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Myopia, or nearsightedness, is a worldwide common type of refractive error. It is a non-life-threatening disorder with huge social and economic consequences due to its increasing prevalence. Axial length (AL) is the primary determinant of non-syndromic myopia. It is a parameter representing the combination of anterior chamber depth, lens thickness and vitreous chamber depth of the eye. AL can also be treated as an endophenotype of myopia and may provide extra advantages in the investigation of its genetic basis. The study of AL will not only identify the determinants of eye elongation, but also provide aetiological evidence for myopia. The purpose of this review is to outline the current state of AL research. Epidemiological evidence, genetic determinants, the relationship with other eye components and relative animal models of AL are summarised.

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Relationship Between Central Corneal Thickness, Refractive Error, Corneal Curvature, Anterior Chamber Depth and Axial Length

Abstract: CCT was not associated with refractive error, corneal curvature, anterior chamber depth and axial length. CCT is an independent factor unrelated to other ocular parameters.

Cited by 100 publications

References 24 publications

The Relationship between Central Corneal Thickness and Intraocular Pressure in Adult Nigerians without Glaucoma

The Relationship between Central Corneal Thickness and Intraocular Pressure in Adult Nigerians without Glaucoma

Optical low-coherence reflectometry enables preoperative detection of zonular weakness in pseudoexfoliation syndrome

Axial Length of Myopia: A Review of Current Research

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