Relationship between depressive symptoms and diabetes among native Hawaiians

Grandinetti, Andrew; Kaholokula, Joseph Keawe‘aimoku; Crabbe, Kamana’opono M.; Kenui, Cynthia K.; Chen, Randi; Chang, Healani K.

doi:10.1016/s0306-4530(99)00047-5

Cited by 53 publications

(47 citation statements)

References 14 publications

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“…20 Management of depression with antidepressant drugs 25 or by non-pharmacological means 26 results in a significant improvement in glycemic control, as evidenced by both a fall in fasting blood glucose in one study 25 and an improvement in glycated haemoglobin level in other reports. [26][27][28] In contrast, treating the depression associated with other disorders like cancer has not improved the outcome of the underlying disease. 29 Our study examined characteristics of patients with type 2 DM at our institution that are known to relate to metabolic syndrome.…”

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confidence: 99%

Type 2 Diabetes and its Association with Hypertension and Depression in an Iraqi Population

Saeed

Al-Dabbagh

2003

Ann Saudi Med

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Background: The association of type 2 diabetes mellitus and hypertension is so high that it cannot be explained on the basis of diabetic nephropathy. This phenomenon has been attributed to a condition known as metabolic syndrome. Depression may be another aspect of metabolic syndrome. Patients and Methods: We conducted a cross-sectional case-control study with 110 patients with type 2 diabetes mellitus (DM) and 110 control subjects of comparable age and sex. We determined the time since diagnosis of diabetes, the presence of hypertension (HT), coronary heart disease, cerebrovascular insufficiency, and depression, and took several anthropometric measurements, including height, weight, body mass index (BMI) waist circumference (WC), waist-to-hip circumference ratio (WHR), triceps skin fold thickness (TSFT), mid-upper arm circumference (MUAC), and mid-upper arm muscle area (MAMA). We also investigated depression in metabolic syndrome by comparing patients with type 2 diabetes alone and with type 2 diabetes and hypertension who attended a diabetes clinic. Results: The prevalence of depression in hypertensive diabetics was 57% whereas in diabetics alone it was 40% ( χ2 =4.3, P<0.05). Likewise, combined hypertension and depression was more common among diabetics than controls (66% vs 25% respectively P<0.01). Conclusion:The presence of combined hypertension and type 2 diabetes should alert the clinician to look for other features of the metabolic syndrome and for associated depression, which should be treated in most cases by pharmacotherapy.

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confidence: 99%

Type 2 Diabetes and its Association with Hypertension and Depression in an Iraqi Population

Saeed

Al-Dabbagh

2003

Ann Saudi Med

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“…The effects were adjusted for demographic, lifestyle, and clinical factors [11,23,38]. For logistic regression, we used the median split method to categorize the variables into binary groups.…”

Section: Discussionmentioning

confidence: 99%

“…Potential confounders and risk factors were identified on the basis of their association with outcomes and a priori knowledge [11,23,38]. Socio-demographic information included age, ethnicity, education, occupation, monthly income, alcohol consumption, and cigarette smoking (non-smokers, past smokers, and current smokers).…”

Section: Assessment Of Covariatesmentioning

confidence: 99%

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Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM)

Hasan

Thiruchelvam

Ahmed

et al. 2014

Int J Diabetes Dev Ctries

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The primary objective of this study was to examine the association between depression, anxiety symptoms, and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM). Another objective was to examine the association between glycemic control and mental status, measured by mental composite score (MCS). This study was conducted on 611 randomly sampled Malaysian women with T2DM who were treated as outpatients at medication therapy adherence clinics (MTAC). The Delusions-Symptoms-States Inventory: State of Anxiety and Depression (DSSI/SAD) and Center for Epidemiologic Studies Depression Scale 10 (CES-D 10) were used. Five most recent readings of hemoglobin A1c (HbA1c), fasting, and random glucose levels were recorded. Regression analysis was used to correlate glycemic control with depression, anxiety symptoms, and MCS, while considering potential confounders. For depression symptoms, an increase of one category was associated with a small average HbA1c increase of 0.10 % (95 % CI −0.38, 0.68), whereas for anxiety symptoms, there was a small decrease in average HbA1c of 0.44 % (95 % CI −1.17, 0.28); both were not significant. Very poorly controlled HbA1c was not significantly associated with symptoms of depression (OR 1.43, 95 % CI 0.45-4.55) or anxiety (OR 0.47, 95 % CI 0.15-1.49). MCS was found to have a strong inverse correlation with HbA1c. That is, women who reported poor MCS had a significantly higher, and therefore very poorly controlled, HbA1c (OR 1.70, 95 % CI 1.01-2.88). The presence of depression and anxiety symptoms was not significantly associated with glycemic control in women with T2DM, supporting the hypothesis that argues against the existence of a link between depression, anxiety, and glycemic control.

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“…Os resultados desta meta-análise se contrapõem aos achados de nossa revisão devido à inclusão de artigos anteriores a 1990 que evidenciaram uma forte associação positiva. Além disso, os estudos publicados após 1999 também correlacionaram a presença de sintomas depressivos a um pior controle glicêmico (8,43).…”

Section: Impacto Da Depressão No Diabetesunclassified

Diabetes mellitus e depressão: uma revisão sistemática

Moreira¹,

Papelbaum²,

Appolinário³

et al. 2003

Arq Bras Endocrinol Metab

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A presença de depressão no paciente com diabetes mellitus (DM) parece relacionar-se a alterações no curso clínico da doença. O objetivo deste trabalho é realizar uma revisão sistemática sobre a associação entre o DM e depressão. Foi realizada uma pesquisa bibliográfica utilizando as bases de dados MEDLINE e LILACS para identificar artigos relevantes, publicados entre 1990 e 2001, que avaliassem esta associação. Foram analisadas informações referentes à prevalência, ao impacto e ao tratamento da depressão no DM. A prevalência de depressão no DM variou de 0 a 60,5%. Sintomas depressivos relacionaram-se a um pior controle glicêmico, a um aumento e a uma maior gravidade das complicações clínicas, a uma piora da qualidade de vida e ao comprometimento de aspectos sociais, econômicos e educacionais ligados ao DM. O tratamento da depressão está relacionado à melhora dos níveis glicêmicos, podendo contribuir para um melhor controle de diversos aspectos relacionados ao DM. The presence of depression in a patient with diabetes mellitus (DM) seems to be related to changes in the clinical course of the disease. The purpose of this study is to perform a systematic review on the association of DM and depression. A bibliographic search was performed using the MEDLINE and LILACS databases to identify relevant articles, published from 1990 to 2001, which evaluate this relationship. Information concerning prevalence, impact and treatment of depression in DM were analyzed. The prevalence of depression varied from 0 to 60.5%. The presence of depressive symptoms were associated with a poor glycemic control, an increase in the number and severity of clinical complications, a worse quality of life and impairment of social, educational and economic aspects related to DM. The treatment of depression is associated with an improvement in glycemic levels, which may contribute to a better control of several aspects related to DM. (Arq Bras Endocrinol Metab 2003;47/1:19-29)

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Relationship between depressive symptoms and diabetes among native Hawaiians

Cited by 53 publications

References 14 publications

Type 2 Diabetes and its Association with Hypertension and Depression in an Iraqi Population

Type 2 Diabetes and its Association with Hypertension and Depression in an Iraqi Population

Relation between mental health-related variables and glycemic control in Malaysian women with type 2 diabetes mellitus (T2DM)

Diabetes mellitus e depressão: uma revisão sistemática

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