Relationship between diabetic nephropathy and depression: a cross-sectional analysis using the Diabetes Study from the Center of Tokyo Women's Medical University (DIACET)

Takasaki, Keiko; Babazono, Tetsuya; Ishizawa, Kaya; Miura, Junnosuke; Uchigata, Yasuko

doi:10.1136/bmjdrc-2016-000310

Cited by 19 publications

(24 citation statements)

References 26 publications

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“…Takasaki et al stated that nephropathy is likely associated with increased depression, which is actually decreased following kidney transplant. 53 Another study stated that not only did retinopathy worsen the presence of depression in diabetic patients but also the depression itself worsened the retinopathy in return. 54 As for strokes, it was well established that history of type 2 DM and a past cardiovascular accident event were highly predictive of depression and could even lead to dementia.…”

Section: Discussionmentioning

confidence: 99%

Diabetes and depression in Lebanon and association with glycemic control: a cross-sectional study

Ahmadieh¹,

Itani²,

Itani³

et al. 2018

DMSO

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BackgroundDiabetes mellitus is a chronic noncommunicable disease characterized by hyperglycemia and is associated with chronic complications affecting the overall quality of life. As of 2017, the prevalence of diabetes in Lebanon is estimated to be 14.6%. Depression is noted to be common among Lebanese citizens, present in around 17.3%. This study aims to investigate the prevalence of depression among the diabetic Lebanese citizens and to study its relationship with poor glycemic control and diabetes complications.MethodsIn total, 436 diabetic patients participated in this cross-sectional study. Patients with diabetes mellitus attending several private clinics and health care centers were asked to fill out a well-structured questionnaire developed by an expert. Depression was assessed using Beck Depression Inventory (BDI). The study collected demographic information about the participants including their lifestyles, their last reported glycosylated hemoglobin values, and their reported microvascular and macrovascular complications. Data were collected, entered, and analyzed on SPSS software version 23.1. A descriptive analysis is carried out by calculating the mean and standard deviation for continuous variables and number and percentage for categorical ones. Association between categorical variables is evaluated using a chi-squared test. A P-value of <0.05 is considered to be significant.ResultsDepression was prevalent among 28.8% of the patients with diabetes mellitus. The average age of participants was 64.08 years. In total, 280 (64.2%) of the participants were females and the average diabetes duration was 8.89 years. There was no significant relationship found between depression and glycemic control. By contrast, a significant association between retinopathy, nephropathy, and stroke and depression was found.ConclusionDepression was found to be present among 28.8% of the patients with diabetes mellitus in Lebanon; however, no association was established between depression and glycemic control.

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Section: Discussionmentioning

confidence: 99%

Diabetes and depression in Lebanon and association with glycemic control: a cross-sectional study

Ahmadieh¹,

Itani²,

Itani³

et al. 2018

DMSO

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“…Yu suggested that depression is associated with proinflammatory cytokines and this proinflammatory state has been linked with an increased risk of diabetic nephropathy. Takasaki (2016) also found that the progression of diabetic nephropathy is likely to be associated with increased risk and severity of depression [21,22].…”

Section: Discussionmentioning

confidence: 99%

The Percentage of Depressive Symptoms in Patients with Type 2 Diabetes Mellitus in M Djamil General Hospital Padang, Indonesia

Decroli¹,

Kam²,

Dillasamola³

2019

jrp

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The objectives of this study are to find the percentage of depressive symptoms and the most appeared clinical manifestation of depressive symptoms. A total of 2016 patient with type 2 diabetes from M Djamil General Hospital had fulfilled the questionnaire we administered. Demographic and clinical data were determined from the patient's medical records. Depressive symptoms defined by The Center for Epidemiologic Studies Depression Scale-Revised (CESD-R) score of 16 or higher. CESD-R consisted of nine symptoms group and a 20-item questionnaire. These symptoms groups in patients with depressive symptoms will be counted. Patients with depressive symptoms were grouped based on a type of diabetic medication they consumed (diet only, oral antidiabetic, and insulin) and diabetic complication. From 2016 patients participated in this study, we found 235 (11.7%) patients were having depressive symptoms. The most appeared clinical manifestation in 235 patients with depressive symptoms is fatigue (88.08%), loss of interest (52.34%), sadness (41.7%), poor concentration (40.42%), and agitation (23.83%). There are more depressive symptoms in patients consuming oral antidiabetic drug than patients using insulin and diet only (70.2 vs. 28.1 vs 1.7%). More depressive symptoms are also found in patients with diabetic nephropathy than patients with diabetic neuropathy and heart disease (52.8 vs. 27.7 vs. 19.6%). These findings showed that there are many depressive symptoms in patients with T2DM, and some of most appeared clinical manifestation in depressive symptoms should be considered.

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“…Indeed, individuals with diabetes have a 2–4 fold greater risk of depression when compared to individuals without diabetes 7 . Depression is associated with higher glycated haemoglobin (HbA1c) 8 , higher rates of complications 9 , 10 and mortality 11 . This association may be mediated by sub-optimal self-care 12 , medication adherence 13 , health-related quality of life 14 and common pathophysiological mechanisms via stress and inflammation 7 .…”

Section: Introductionmentioning

confidence: 99%

Depression and diabetes distress in adults with type 2 diabetes: results from the Australian National Diabetes Audit (ANDA) 2016

Nanayakkara

Pease

Ranasinha

et al. 2018

Sci Rep

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This study explores the prevalence of, and factors associated with, likely depression and diabetes distress in adults with type 2 diabetes in a large, national sample. Australian National Diabetes Audit data were analysed from adults with type 2 diabetes attending 50 diabetes centres. The Brief Case find for Depression and Diabetes Distress Score 17 were administered to screen for likely depression and diabetes-related distress, respectively. A total of 2,552 adults with type 2 diabetes participated: (mean ± SD) age was 63 ± 13 years, diabetes duration was 12 ± 10 years, and HbA1c was 8 ± 2%. Twenty-nine percent of patients had likely depression, 7% had high diabetes distress, and 5% had both. Difficulty following dietary recommendations, smoking, forgetting medications, and diabetes distress were all associated with greater odds of depression whereas higher own health rating was associated with lower odds (all p < 0.02). Female gender, increasing HbA1c, insulin use, difficulty following dietary recommendations and depression were all associated with greater odds of diabetes distress & older age, higher own health rating and monitoring blood glucose levels as recommended were associated with lower odds (all p < 0.04). Depression was associated with sub-optimal self-care, while diabetes distress was associated with higher HbA1c and sub-optimal self-care.

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Relationship between diabetic nephropathy and depression: a cross-sectional analysis using the Diabetes Study from the Center of Tokyo Women's Medical University (DIACET)

Cited by 19 publications

References 26 publications

Diabetes and depression in Lebanon and association with glycemic control: a cross-sectional study

Diabetes and depression in Lebanon and association with glycemic control: a cross-sectional study

The Percentage of Depressive Symptoms in Patients with Type 2 Diabetes Mellitus in M Djamil General Hospital Padang, Indonesia

Depression and diabetes distress in adults with type 2 diabetes: results from the Australian National Diabetes Audit (ANDA) 2016

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