Relationship between psychosocial adjustment and executive function in patients with bipolar disorder and schizophrenia in remission: the mediating and moderating effects of insight

Yen, Cheng Fang; Chêng, Chu-yüan; Huang, Chi Fen; Ko, Chih Hung; Yen, Ju-Yu; Chang, Yu Ping; Chen, Cheng Sheng

doi:10.1111/j.1399-5618.2008.00650.x

Cited by 26 publications

(25 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Executive function had a directly positive effect on psychosocial adjustment in both patients with BD and SZ. There were positive correlations between insight and executive function among subjects with SZ and BD, suggesting that the ability to recognize their own experiences of illness seems to be the first step to developing an effective strategy for supplementing their deficiencies in psychosocial adjustment (44). The possibility of a shared general cognitive impairment might yet be possible as an explanation, due to comparable qualitative scores shown by the two conditions; nevertheless these abnormalities oftentimes are larger in SZ patients.…”

Section: Discussionmentioning

confidence: 99%

Cognitive Impairment in Bipolar Disorder and Schizophrenia: A Systematic Review

Vöhringer¹,

Barroilhet²,

Amerio³

et al. 2013

Front. Psychiatry

142

View full text Add to dashboard Cite

Aims: Previous comparisons of cognitive decline among patients with bipolar disorder (BD) and schizophrenia (SZ) have found somehow quite similar profiles of deficits, but results have varied between studies. Therefore an extensive and thoughtful systematic review of the matter is warranted.Methods: Studies were found through systematic search (PubMed) following PRISMA guidelines. To be included, studies must have assessed the following cognitive functions: executive functions, memory, IQ, attention-concentration, and perceptuomotor function. In order to make comparison between the two entities, studies should include BD patients with operationally defined euthymia, schizophrenic patients in remission, and third group of healthy control patients. Comparisons were made after controlling for years of schooling and residual affective symptoms.Results: We found that overall both SZ and BD patients present deficits on all neurocognitive measures compared to healthy controls. In particular, SZ patients show more severe and pervasive cognitive deficits while BD patients present a milder and more confined impairment. In addition, evidence from the literature suggests that SZ and BD patients share a similar cognitive impairment profile with different degrees of deficits. Therefore, the difference between the two groups seems to be more quantitative (degree of deficit) rather than qualitative (profile), supporting a dimensional approach to the two clinical entities. Limitations of the present review includes the impossibility to control for effects of medication, varying time required for assessment across studies, illness diagnosis reliability, and course severity.Conclusion: Patients with BD might exhibit a cognitive impairment that could be similar to SZ in terms of their profile, although patients with SZ may have more severe and widespread impairments.

show abstract

Section: Discussionmentioning

confidence: 99%

Cognitive Impairment in Bipolar Disorder and Schizophrenia: A Systematic Review

Vöhringer¹,

Barroilhet²,

Amerio³

et al. 2013

Front. Psychiatry

142

View full text Add to dashboard Cite

show abstract

“…As there is some evidence indicating that males are at increased risk of unfavourable psychosocial outcome in BD (Tohen et al, 1990;Yen et al, 2009), it is possible that gender related differences in emotion recognition contribute to psychosocial impairments in males with the disorder. Indeed, there is growing support for the notion that intact social cognition plays a vital role in healthy psychosocial function (Hoertnagl et al, 2011;Martino et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Auditory-prosodic processing in bipolar disorder; from sensory perception to emotion

Rheenen

Rossell

2013

Journal of Affective Disorders

View full text Add to dashboard Cite

“…Recovery of past social functional levels was attained by only 45% of type I BPD patients within nine years (Carlson et al, 1974). Factors suggested as potentially related to high rates of sustained social dysfunction despite treatment include residual depressive symptoms, limited illness-insight, and impaired executive functioning (Gitlin et al, 1995; Yen et al, 2007; Yen et al, 2009). However, since studies of factors associated with social functional recovery defined as regaining one's own premorbid or highest previous level of social functioning remain rare, we investigated demographic, clinical, and neurocognitive factors associated with social functional recovery among euthymic or only mildly depressed BPD subjects, in the community.…”

Section: Introductionmentioning

confidence: 99%

Correlates of recovery of social functioning in types I and II bipolar disorder patients

Wingo

Baldessarini

Compton

et al. 2010

Psychiatry Research

View full text Add to dashboard Cite

Since bipolar disorder (BPD) patients are often functionally impaired, and factors associated with recovery from disability are largely unknown, we investigated demographic, clinical, and neurocognitive correlates of current social functional recovery in 65 stable participants diagnosed with DSM-IV type I (n=42) or II (n=23) BPD. Regaining highest previous levels of social functioning was rated with the Interpersonal Relationships Questionnaire. We also considered neuropsychological test findings as well as demographic and clinical information including mania and depression symptom-ratings. We examined factors associated with social recovery status using univariate analyses and then multiple logistic regression modeling. Of all subjects, 30 (46%) achieved current social functional recovery and 35 (54%) did not. Younger age (p=0.005) and lesser current depressive symptoms (p=0.02) were associated with social functional recovery, even after controlling for time since the last major mood episode, diagnostic type (II vs. I), co-morbid psychiatric illness, and executive functioning status. The findings are consistent with deleterious effects of even residual depressive symptoms in BPD patients.

show abstract

Relationship between psychosocial adjustment and executive function in patients with bipolar disorder and schizophrenia in remission: the mediating and moderating effects of insight

Cited by 26 publications

References 55 publications

Cognitive Impairment in Bipolar Disorder and Schizophrenia: A Systematic Review

Cognitive Impairment in Bipolar Disorder and Schizophrenia: A Systematic Review

Auditory-prosodic processing in bipolar disorder; from sensory perception to emotion

Correlates of recovery of social functioning in types I and II bipolar disorder patients

Contact Info

Product

Resources

About