Relationship between second‐generation frequency doubling technology and standard automated perimetry in patients with glaucoma

Zarkovic, Andrea; Mora, Justin; McKelvie, James; Gamble, Greg

doi:10.1111/j.1442-9071.2007.01629.x

Cited by 12 publications

(7 citation statements)

References 11 publications

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“…Subdivided into quadrants, only the nasal inferior quadrant in healthy subjects (r = 0.53, p<0.005) and the temporal inferior and nasal inferior quadrants in ocular hypertensive subjects (r = 0.45 and r = 0.53, p≤0.005) were significantly correlated. This differs from the results reported by Zarkovic et al [6] who reported the highest correlation in glaucoma patients in the superior hemifields and supero-nasal quadrants.…”

Section: Discussioncontrasting

confidence: 99%

“…Other investigations found good correlations between SAP and Matrix-FDT in glaucoma patients. [1], [6], [9], [10] Artes et al compared SAP and Humphrey Matrix in a small study of 15 glaucoma patients. Their global visual field indices mean deviation (MD) and pattern standard deviation (PSD) correlated highly (r = 0.86, p<0.001; r = 0.95, p<0.001, repectively).…”

Section: Discussionmentioning

confidence: 99%

“…It utilizes additional tests to improve the spatial resolution of visual field defects by using smaller targets with a higher spatial frequency and a lower temporal frequency. [6], [7] Comparison with standard FDT perimetry suggests that Matrix perimetry may have higher sensitivity for early glaucomatous loss and better characterization of the pattern of visual field loss. [8] Therefore, Matrix perimetry may provide additional benefits for monitoring subtle progression in glaucomatous field defects.…”

Section: Introductionmentioning

confidence: 99%

“…[18] Whereas a large number of studies have been published in the past comparing the first-generation FDT with standard automated perimetry, fewer studies have compared the second generation Matrix-FDT with SAP. The majority of these studies included glaucoma patients, [1], [2], [6], [7], [10], [19], [20] whereas only few studies included ocular hypertensive subjects. [9], [13] Persons with ocular hypertension have an increased risk of developing glaucoma during their lifetime.…”

Section: Introductionmentioning

confidence: 99%

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Standard Automated Perimetry versus Matrix Frequency Doubling Technology Perimetry in Subjects with Ocular Hypertension and Healthy Control Subjects

Lamparter¹,

Aliyeva²,

Schulze³

et al. 2013

PLoS ONE

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BackgroundTo evaluate the relationship and agreement between standard automated perimetry (SAP) and Matrix frequency doubling technology (Matrix-FDT) in subjects with ocular hypertension and healthy control subjects.MethodsForty-four eyes of 44 ocular hypertensive subjects and 29 eyes of 29 healthy age-matched control subjects were included in this prospective study. All participants underwent complete ophthalmic examination, including slit-lamp biomicroscopy, intraocular pressure measurement, pachymetry, and dilated fundus examination, and showed reliable visual field tests. One randomly selected eye of each participant was examined with SAP (Swedish Interactive Threshold Algorithm [SITA] Standard 24-2 test) and Matrix-FDT (24-2 threshold test), in random order. Correlations between global indices (MD, PSD), regions (2 hemifields, 4 quadrants, 6 sectors) and 52 single field positions were analyzed using Spearman’s rank correlation coefficient.ResultsIn both groups, mean deviation values of SAP and Matrix-FDT correlated significantly (OHT subjects: r = 0.47, p<0.005; healthy subjects: r = 0.68; p<0.001, respectively). Pattern standard deviation of SAP and Matrix-FDT showed no significant correlation in healthy subjects but correlated significantly in ocular hypertensive subjects (r = 0.45, p<0.005). In healthy subjects, a significant correlation between SAP and Matrix-FDT was shown in the supero-temporal and infero-temporal sectors of the disc (r = 0.40 and r = 0.38, p<0.05, respectively). In OHT subjects, supero-temporal, supero-nasal and nasal sectors correlated significantly (r = 0.49, 0.62 and 0.38, p≤0.01, respectively). The correlation pattern of individual visual field test locations appeared heterogeneous in both groups.ConclusionsIn both, ocular hypertensive and healthy subjects SAP and Matrix-FDT correlate well. In ocular hypertensive subjects, both techniques showed good correlation in the supero-temporal, supero-nasal, and nasal sectors of the disc. Poor agreement was found in the temporal, infero-temporal and infero-nasal disc sectors. This missing correlation might be related to early retinal nerve fiber layer damage in these regions of the disc, recognized by one of the visual field instruments.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Standard Automated Perimetry versus Matrix Frequency Doubling Technology Perimetry in Subjects with Ocular Hypertension and Healthy Control Subjects

Lamparter¹,

Aliyeva²,

Schulze³

et al. 2013

PLoS ONE

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“…In agreement with the previous studies, 16,18 we found the test duration of FDT-Matrix to be significantly shorter than that of SAP-SITA. This difference may be explained by the different algorithms used by these tests.…”

supporting

confidence: 82%

Glokom ve Oküler Hipertansiyon Hastalarında Humphrey Matriks Perimetrisi ve Standart Otomatik Perimetrinin SITA Stratejisi ile Elde Edilen Görme Alanı Sonuçlarının Karşılaştırılması

Yılmaz¹,

Bozkurt²,

İrkeç³

2011

tjo

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SummaryPurpose: To compare the results of Humphrey Matrix 30-2 full threshold test and standard automated perimetry (SAP) using the Swedish Interactive Threshold Algorithm (30-2 SITA standard strategy). Material and Method: Test duration, mean deviation (MD), pattern standard deviation (PSD), number of depressed points on pattern deviation plot (PDP) at level of p<0.05 and p<0.01 were compared using the Wilcoxon signed-rank test. The correlations between MD, PSD and the number of depressed points were analyzed using Spearman's rank correlation coefficient. Kappa (κ) statistic was used to determine the strength of agreement between Matrix and SAP-SITA tests. Results: PSD was higher in Matrix perimetry and the number of depressed points at level of p<0.05 was significantly higher in SAP-SITA test. MD (r=0.48), PSD (r=0.58) and the number of points depressed on PDP at the level of <0.05 and <0.01 (r=0.48 and r=0.47, respectively) showed moderate correlations between the two tests (p<0.001). The agreement between SAP and Matrix perimetry was found to be moderate (κ=0.44, p<0.001). ÖzetAmaç: Humphrey Matriks 30-2 tam eflik testi sonuçlar› ile ‹sveç interaktif eflik algoritmas›n› (30-2 SITA standart stratejisi) kullananan standart otomatize perimetri (SAP) sonuçlar›n› karfl›laflt›rmak. Gereç ve Yöntem: Test süresi, ortalama deviasyon (MD), patern standart deviasyon (PSD) ile patern deviasyon haritas›nda p<0,05 ve p<0,01 düzeyinde bask›lanm›fl nokta say›lar› Wilcoxon signed rank testi ile karfl›laflt›r›ld›. ‹ki testteki MD, PSD ve bask›lanm›fl nokta say›lar› aras›ndaki korelasyon Spearman korelasyon katsay›s› kullan›larak analiz edildi. Matriks ve SAP SITA testleri aras›ndaki uyumun de¤erlendirilmesinde kappa (κ) istatisti¤i kullan›ld›. Sonuçlar: PSD'nin matriks perimetride, p<0,05 seviyesinde bask›lanm›fl nokta say›s›n›n ise SAP-SITA testinde istatistiksel aç›dan anlaml› oranda yüksek oldu¤u saptand›. ‹ki test aras›nda MD (r=0,48), PSD (r=0,58) ve Patern deviasyon haritas›nda p<0,05 ve p<0,01 düzeyinde bask›lanm›fl noktalar›n say›s› (r=0,48 and r=0,47, s›ras›yla) aras›nda orta derecede korelasyon oldu¤u görüldü (p<0,001). SAP ve Matriks perimetri aras›ndaki uyumun orta düzeyde oldu¤u saptand› (κ=0,44, p<0,001). Tart›flma: ‹ki perimetrideki görme alan› indeksleri ve patern deviasyon haritas›ndaki bask›lanm›fl noktalar›n say›s› yaln›zca orta düzeyde korelasyon göstermektedir. Bu nedenle Matriks perimetri ve SAP'da ki global indeksler ve test noktalar› aras›nda do¤rudan bir karfl›laflt›rma yap›lmamal›d›r. (Turk J Ophthalmol 2011; 41: 98-103) Anahtar Kelimeler: Frekans çiftleme teknolojisi, glokom, humphrey matriks perimetri, SITA stratejisi, standart otomatize perimetre

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Frequenzverdopplungsperimetrie

Lamparter

Schulze

Em³

2009

Ophthalmologe

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Glaucoma is a disease in which death of retinal ganglion cells is associated with loss of visual function. The gold standard for visual field testing has been standard automated perimetry (SAP). However, up to 30-50% of retinal ganglion cells must be lost before a scotoma is detected with SAP. Therefore, investigators have been interested in finding diagnostic techniques that would allow earlier detection of visual field loss than that detected by standard white-on-white perimetry. Frequency-doubling technology (FDT) has been suggested as a promising technique that may detect glaucomatous ganglion cell damage earlier than SAP by targeting a sparsely spaced subsystem of Mgamma retinal ganglion cells where cell damage is less masked by redundancy. The second generation of FDT perimetry, the Matrix FDT, was released with the intention of improving the spatial resolution of visual field defects. In this article we present FDT and discuss data that compare FDT with standard white-on-white perimetry.

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Relationship between second‐generation frequency doubling technology and standard automated perimetry in patients with glaucoma

Abstract: Generally, the Matrix and Humphrey Field Analyser perimetry correlate well; however, each machine utilizes a different method of analysing data and thus the direct comparison should be made with caution.

Cited by 12 publications

References 11 publications

Standard Automated Perimetry versus Matrix Frequency Doubling Technology Perimetry in Subjects with Ocular Hypertension and Healthy Control Subjects

Standard Automated Perimetry versus Matrix Frequency Doubling Technology Perimetry in Subjects with Ocular Hypertension and Healthy Control Subjects

Glokom ve Oküler Hipertansiyon Hastalarında Humphrey Matriks Perimetrisi ve Standart Otomatik Perimetrinin SITA Stratejisi ile Elde Edilen Görme Alanı Sonuçlarının Karşılaştırılması

Frequenzverdopplungsperimetrie

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