2020
DOI: 10.1002/celc.201901703
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Relationship Between Sweat and Blood Lactate Levels During Exhaustive Physical Exercise

Abstract: In contrast to the generally accepted view, that sweat lactate is irrelevant to blood, we report on the suitability of sweat lactate for diagnostics. We demonstrate a significant increase in lactate concentration in sweat from the working muscle area simultaneously with the rise of blood lactate content during exhaustive physical exercise. The variation rates of lactate concentration in sweat from working and latent muscle areas correlate positively with blood lactate levels (r>0.8 and r=0.7, respectively), th… Show more

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Cited by 65 publications
(66 citation statements)
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“…For example, blood glucose level is an indicator of diabetes: hyperglycemia and hypoglycemia, [190][191] blood lactate level can predict multiple system organ failure (MSOF) caused by septic shock 192 and ischemia and inadequate oxygenation 193 . Over the years, a number of enzyme-mimicking nanostructured materils 188,[193][194][195][196][197][198][199][200][201][202][203][204] have been used for the detection of glucose, 194-197, 202, 203 lactate, 193,[198][199]204 uric acids, 200 kanamycin, 188 and arsenet 201 . In this section, nanozyme based electrochemical sensor for glucose detection is briefly discussed.…”
Section: Small Molecule Detectionmentioning
confidence: 99%
“…For example, blood glucose level is an indicator of diabetes: hyperglycemia and hypoglycemia, [190][191] blood lactate level can predict multiple system organ failure (MSOF) caused by septic shock 192 and ischemia and inadequate oxygenation 193 . Over the years, a number of enzyme-mimicking nanostructured materils 188,[193][194][195][196][197][198][199][200][201][202][203][204] have been used for the detection of glucose, 194-197, 202, 203 lactate, 193,[198][199]204 uric acids, 200 kanamycin, 188 and arsenet 201 . In this section, nanozyme based electrochemical sensor for glucose detection is briefly discussed.…”
Section: Small Molecule Detectionmentioning
confidence: 99%
“…Indeed, with specific regard to lactate, this is still a matter of huge debate. There are a significant number of published works reporting a strong correlation between lactate levels in sweat and in venous blood, [ 78 , 79 ], while there are also a number of reports that cast doubt over whether sweat lactate levels really are reflective of those in the blood, [ 80 , 81 ] and are more likely derived metabolically from blood glucose rather than from blood lactate. It is also important to note that lactate levels in sweat are somewhat higher than those seen in blood, with the biologically relevant lactate levels in sweat for a healthy individual ranging from 5 to 25 mM [ 44 , 75 ] and increasing 10-fold during physical exertion [ 82 ].…”
Section: Current Non-invasive Technology For Lactate Measurements mentioning
confidence: 99%
“…These sweat glands produce and excrete an acidic fluid directly to the outer skin surface through microscale pores [23,68]. Moreover, sweat includes various molecules, e.g., lactate [133,[138][139][140], glucose [69,134,137,141,142], cortisol [23,54,135,[142][143][144], testosterone [23], uric acid, as well as larger molecules, like proteins, peptides, and cytokines [24,54,142], Additionally, the detection of analytes in sweat is feasible due to the given correlation between the blood analyte concentration and the excreted sweat analyte concentration [138,145,146]. For analytes like hormones (cortisol, testosterone), potassium, and different drugs, e.g., alcohol, a strong sweat-blood correlation was proven [23].…”
Section: Biosensors Operating In Sweatmentioning
confidence: 99%