Relationship of admission hematological indexes with myocardial reperfusion abnormalities in acute ST segment elevation myocardial infarction patients treated with primary percutaneous coronary interventions

Maden, Orhan; Kacmaz, Fehmi; Selçuk, Hatice; Selçuk, Mehmet Timur; Aksu, Tolga; Tüfekçioğlu, Omaç; Senen, Emir K.; Balbay, Yücel; İlkay, Erdoğan

doi:10.1016/s0828-282x(09)70090-x

Cited by 38 publications

(37 citation statements)

References 30 publications

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“…Furthermore, Sabatine et al [26] found that an elevated baseline WBC count correlated with impaired myocardial perfusion and increased 6-month mortality in patients with STEMI. Maden et al [27] showed that higher WBC and MPV is associated with occluded IRA in patients with STEMI. Karahan et al [28] observed that increased WBC and MPV are independent predictors of impaired microvascular perfusion in patients with STEMI.…”

Section: Discussionmentioning

confidence: 99%

White blood cell count to mean platelet volume ratio: A novel and promising prognostic marker for ST-segment elevation myocardial infarction

et al. 2016

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Background: Increased white blood cell (WBC) count is associated with increased mortality in patients with ST-segment elevation myocardial infarction (STEMI Results: WMR has the highest area under receiver operating characteristic (ROC) curve and pairwise comparisons of the ROC curves revealed that WMR has the higher discriminative ability for long-term mortality than WBC, MPV, red blood cell distribution with (RDW), WBC-MPV combination, and platelet to lymphocyte ratio and neutrophil to lymphocyte ratio (PLR-NLR) combination in patients undergoing PLR-NLR and WBC-MPV combinations. (Cardiol J 2016; 23, 3: 225-235) Key words: mean platelet volume, ST-segment elevation myocardial infarction, white blood cell Introductıon

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Section: Discussionmentioning

confidence: 99%

White blood cell count to mean platelet volume ratio: A novel and promising prognostic marker for ST-segment elevation myocardial infarction

et al. 2016

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“…thromboxane A2 and B2, platelet factor 4, P-selectin, platelet-derived growth factor) and expression of adhesive receptors (glycoprotein IIb/IIIa) [2]. Furthermore, increased MPV values are associated with shortened bleeding time [3].…”

Section: Karolina Supel Et Al Mpv and Its Prognostic Value In Acs Cmentioning

confidence: 99%

Mean platelet volume and its prognostic value in acute coronary syndrome complicated by cardiogenic shock

Supel

Salska²,

Jaskiewicz³

et al. 2013

Cardiol J

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“…Previous studies have demonstrated a close relationship between MPV and AMI [8], unstable coronary syndromes [26], slow coronary ow [27] and coronary artery ectasia development [28]. High MPV values were found to be associated with unsuccessful reperfusion a er both primary percutaneous coronary intervention and brinolytic therapy [29,30]. In addition, increased platelet activity may be associated with recurrent thrombotic events and no-re ow phenomenon, which are, in turn, associated with poorer le ventricular function.…”

Section: Discussionmentioning

confidence: 99%

Relationship between mean platelet volume and left ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction

Yazici

Poyraz²,

Şen³

et al. 2011

CIM

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Relationship between mean platelet volume and le ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction Abstract Purpose: Mean platelet volume (MPV) is an indicator of platelet activation, which is a central process in the pathophysiology of coronary heart disease. Metabolic syndrome (MS) may lead to worsened le ventricular systolic function by causing recurrent thrombotic events and by aggravating systemic in ammation in the course of acute myocardial infarction. e present study was designed to investigate the relationship between MPV and le ventricular systolic function in patients with metabolic syndrome who had rst ST-elevation myocardial infarction.Methods: MPV was measured on admission in 33 patients who had preserved le ventricle systolic function (mean age, 56.9±10.2 years) and in 48 patients who had depressed le ventricle systolic function (mean age, 57.9±10.5 years) with metabolic syndrome and rst ST elevation myocardial infarction. Depressed le ventricle systolic function was de ned as ≤50% ejection fraction value. MPV levels were compared in the two groups.Results: MPV was signi cantly higher in patients with depressed le ventricle systolic function in comparison with patients showing preserved le ventricle systolic function (p=0.02). Logistic regression analysis showed an independent relationship between MPV and deteriorated le ventricular systolic function, even a er adjustment for potential confounders (1.08 (1.04-1.20), CI: 95%, p=0.02).Conclusions: Increased MPV on admission can be associated with degree of le ventricle systolic depression in patients with metabolic syndrome with rst ST-elevation myocardial infarction. MPV may prove to be useful as a prognostic marker in patients with metabolic syndrome and ST elevation MI.

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Relationship of admission hematological indexes with myocardial reperfusion abnormalities in acute ST segment elevation myocardial infarction patients treated with primary percutaneous coronary interventions

Cited by 38 publications

References 30 publications

White blood cell count to mean platelet volume ratio: A novel and promising prognostic marker for ST-segment elevation myocardial infarction

White blood cell count to mean platelet volume ratio: A novel and promising prognostic marker for ST-segment elevation myocardial infarction

Mean platelet volume and its prognostic value in acute coronary syndrome complicated by cardiogenic shock

Relationship between mean platelet volume and left ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction

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