Relationship of central corneal thickness to postural IOP changes in patients with and without glaucoma in southern India

Moster, Stephen J; Fakhraie, Ghasem; Venketesh, Rengaraj; Moster, Mark L.; Zhao, Yuanjun; Moster, Marlene R.

doi:10.1007/s10792-012-9522-8

Cited by 10 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the other study, Singleton et al [11] compared postural changes in IOP in only 11 normal subjects, relative to several groups of patients who had different types of autonomic dysfunction; they concluded that no statistically significant postural changes in IOP occurred in normal subjects. Additionally, multiple authors reported measuring IOP in sitting and supine positions using different devices, such as the ICP [16], TonoPen [17,18,19,20,21], and AVIA [13]. Some others compared different tonometers [13,22], but we found no reports of IOP measurements in subjects in the ST position.…”

Section: Discussionmentioning

confidence: 64%

“…In another study, IOP was measured in 19 healthy young Korean subjects in the sitting and supine positions, revealing an increase of approximately 3 mmHg from the first to the second position [19]. In another investigation, the same device was used to measure IOP in both sitting and supine positions in 45 glaucoma patients and 46 healthy subjects; both groups showed a statistically significant increase in mean IOP from the sitting position to supine position, which was higher in glaucomatous patients (2.3 mmHg) than in healthy subjects (1.2 mmHg) [21].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Intraocular Pressure Measurements in Standing Position with a Rebound Tonometer

et al. 2019

View full text Add to dashboard Cite

Background and Objectives: It has been established that body position can play an important role in intraocular pressure (IOP) fluctuation. IOP has been previously shown to increase significantly when lying down, relative to sitting; this type of investigation has not been extensively reported for the standing (ST) position. Therefore, this study aims to look for eventual significant IOP changes while ST, sitting, and lying down. Materials and Methods: An Icare PRO was used to measure the IOP of 120 eyes of 60 healthy individuals, with age ranging from 21 to 55 years (mean 29.22 ± 9.12 years), in sitting, supine and ST positions; IOP was measured again, 5 min after standing (ST-5m). Results: Mean IOP difference between sitting and ST position was 0.39 ± 1.93 mmHg (95% CI: 0.04 to 0.74 mmHg) (p = 0.027); between sitting and ST-5m, it was −0.48 ± 1.79 mmHg (95% CI: −0.8 to −0.16 mmHg) (p = 0.004); between the sitting and supine position, it was −1.16±1.9 mmHg (95% CI: −1.5 to −0.82 mmHg) (p < 0.001); between the supine and ST position, it was 1.55 ± 2.04 mmHg (95% CI: 1.18 to 1.92 mmHg) (p < 0.001); between supine and ST-5m, it was 0.68 ± 1.87 mmHg (95% CI: 0.34 to 1.02 mmHg) (p < 0.001); and between ST-5m and ST, it was 0.94 ± 1.95 mmHg (95% CI: 0.58 to 1.29 mmHg) (p < 0.001). Mean axial eye length was 24.45 mm (95% CI: 24.22 to 24.69 mm), and mean central corneal thickness was 535.30 μm (95% CI: 529.44 to 541.19 μm). Conclusion: Increased IOP in the ST-5m position suggests that IOP measurements should be performed in this position too. The detection of higher IOP values in the ST-5m position than in the sitting one, may explain the presence of glaucoma damage or progression in apparently normal-tension or compensated patients.

show abstract

Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Intraocular Pressure Measurements in Standing Position with a Rebound Tonometer

et al. 2019

View full text Add to dashboard Cite

show abstract

“…In healthy subjects, the increase in IOP between sitting and supine position was reported as 1.8 mmHg using Perkins applanation tonometer, 2.5-3.9 mmHg with pneumotonometer, 1.2 mmHg with Tono-Pen, and 4.1 mmHg with Goldman applanation tonometry. 1,26,27,28,29 Mosaed et al 30 reported relatively small postural change in IOP in healthy young adults and elderly individuals with healthy eyes, while another study reported that postural IOP changes in these two populations were nonsignificant. 31…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Effect of Body Position on Intraocular Pressure Measured with Rebound Tonometer

Mayalı¹,

Tekin²,

Kayıkçıoğlu³

et al. 2019

tjo

View full text Add to dashboard Cite

Objectives:It is important to determine variables that influence intraocular pressure (IOP) measurement. This study aimed to evaluate the effect of body position on IOP.Materials and Methods:The study included 52 right eyes of 52 patients who presented to the ophthalmology department of our hospital and had no ocular disease except refractive errors. IOP was measured with an Icare PRO tonometer while patients were in sitting, standing, and supine positions, with intervals of 10 minutes between the positions. Correlations between the results were evaluated using Spearman’s correlation analysis and Wilcoxon tests.Results:Thirty-six of the 52 patients were female, 16 were male. Mean age was 31.65±6.30 (23-47) years. Mean IOP values in the sitting, standing, and lying positions were 17.76±3.41 (12.70-25.60) mmHg, 17.10±3.27 (11.50-25.20) mmHg, and 18.46±4.67 (10.50-29.40) mmHg, respectively. There were no statistically significant differences between measurements taken in the different positions (p=0.112, p=0.472, p=0.071). We observed that there was no relationship between age and body position (p>0.45, p>0.79, p>0.77) or between gender and position (p>0.59, p>0.69, p>0.54).Conclusion:Gender and age had no effect on IOP measured in different body positions. There were also no significant differences between IOP values measured in the different positions. Therefore, we believe the portable Icare PRO tonometer can be used for patients who are confined to bed and will provide IOP measurements that are concordant with values obtained while sitting.

show abstract

“…17,18 Thus, parameters including cup-to-disc ratio, retinal nerve fiber layer, and visual field assessment should be used in patients with MC with raised IOP. 19…”

Section: Discussionmentioning

confidence: 99%

Corneal Biometric Parameters and Refractive Properties in Microcornea With Normal Axial Length

Jiang

Wang²,

Chen³

et al. 2021

Cornea

View full text Add to dashboard Cite

Purpose:The purpose of this study was to evaluate the features of and relationships among corneal diameter, central corneal thickness (CCT), endothelial cell density (ECD), and corneal refractive properties in cases of microcornea (MC) with normal axial length.Methods:We included 22 patients (35 eyes) with MC and cataracts and 41 patients (48 eyes) with isolated cataracts as age-matched controls. They were divided into patients with MC younger than 18 years (MC-child), patients with MC 18 years or older (MC-adult), children with congenital cataracts (CCs), and adults with senile cataracts (SCs). Corneal diameter, axial and anterior chamber length, and keratometry were measured; central corneal endothelial cell imaging was performed.Results:The mean horizontal corneal diameter was 7.71 ± 1.51 and 8.78 ± 0.52 mm in MC-child and MC-adult groups, respectively, and 11.89 ± 0.59 and 11.52 ± 2.42 mm in child and adult controls, respectively. The mean CCT was 641.26 ± 63.37 (MC-child) and 617.38 ± 45.40 mm (MC-adult), and 554.92 ± 34.64 (CC) and 551.58 ± 28.47 mm (SC). The mean ECD was 2898.47 ± 443.90 (MC-child) and 2825.81 ± 484.65 cells/mm2 (MC-adult), and 3155.13 ± 372.67 (CC) and 2749.33 ± 399.63 cells/mm2 (SC). The average keratometry was 44.22 ± 3.14 D (MC-child) and 43.86 ± 2.59 D (MC-adult), and 44.19 ± 1.44 D (CC) and 43.94 ± 1.34 D (SC).Conclusions:Patients with MC and normal axial length possess specific parameters, including significantly smaller corneal diameter and thicker CCT than the patients in the control groups. There were no significant differences in ECD and average keratometry. These parameters should be taken into account in the follow-up and treatment.

show abstract

Relationship of central corneal thickness to postural IOP changes in patients with and without glaucoma in southern India

Cited by 10 publications

References 16 publications

Intraocular Pressure Measurements in Standing Position with a Rebound Tonometer

Intraocular Pressure Measurements in Standing Position with a Rebound Tonometer

Evaluation of the Effect of Body Position on Intraocular Pressure Measured with Rebound Tonometer

Corneal Biometric Parameters and Refractive Properties in Microcornea With Normal Axial Length

Contact Info

Product

Resources

About