Relationship of Melanin Degradation Products to Actual Melanin Content: Application to Human Hair

Borges, Chad R.; Roberts, Jeanette C.; Wilkins, Diana G.; Rollins, Douglas E.

doi:10.1006/abio.2000.4976

Cited by 84 publications

(68 citation statements)

References 32 publications

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“…In the presence of cysteine or glutathione, dopaquinone is converted to cysteinyl DOPA or glutathione DOPA. Subsequently, pheomelanin, a yellowred pigment, is formed (Raper, 1928;Kobayashi et al, 1995;Borges et al, 2001), presented in simplified form in Fig. 2.…”

Section: Melanin Formation and Distribution In The Skinmentioning

confidence: 97%

Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries

Parvez

Kang

Chung

et al. 2007

Phytotherapy Research

366

260

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Tyrosinase is a copper-containing enzyme, which is widely distributed in microorganisms, animals and plants and is a key enzyme in melanin biosynthesis, involved in determining the color of mammalian skin and hair. In addition, unfavorable enzymatic browning of plant-derived foods by tyrosinase causes a decrease in nutritional quality and economic loss of food products. The inadequacy of current conventional methods to prevent tyrosinase action encourages researchers to seek new potent tyrosinase inhibitors for food and cosmetics. This article presents a study on the importance of tyrosinase, biochemical characteristics, type of inhibitions, activators from various natural sources with its clinical and industrial importance in recent prospects is discussed in this paper.

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Section: Melanin Formation and Distribution In The Skinmentioning

confidence: 97%

Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries

Parvez

Kang

Chung

et al. 2007

Phytotherapy Research

366

260

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show abstract

“…[30] Generalizing, dark hairs have more melanin and more photosensitive amino acids than light hairs. Melanin can attribute photoprotection to hair protein, but only in the cortex.…”

Section: Photolightening Of Hair Melaninmentioning

confidence: 99%

Photoaggravation of hair aging

Lee

2009

Int J Trichol

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Photoaggravation of hair aging includes various chemical and physical changes in fiber properties which lead to an increase in fiber porosity, loss of mechanical strength and an increase in surface roughness. These changes come from lipid oxidation, disulfide bond cleavage, tryptophan degradation and cysteic acid formation. Hair exposed to sunlight is claimed to be more brittle, stiffer and drier than before irradiation and exhibits a reduced water-absorption capacity. Hair pigments function to provide photochemical protection to hair proteins. Hair pigments accomplish this protection by absorbing and filtering the impinging radiation and subsequently dissipating this energy as heat. However, in the process of protecting the hair proteins from light, the pigments are degraded or bleached. Dark hair is more resistant to photodegradation than light hair, because of the higher photostability of eumelanin compared to pheomelanin. Integral lipids of hair fibers are degraded by ultraviolet light, as well as by visible light, helping to explain the weakening of the cell membrane complex exposed to light radiation.

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“…According to Borges et al [27], black hair contains more or less 99% eumelanin and 1% pheomelanin, darkbrown and blond hairs 95% and 5%, and red hair 67% and 33%. These authors quantified the amounts of eumelanin and pheomelanin of 44 volunteers with different hair types.…”

Section: Susceptibility Of the Different Hair Types To Photodegradationmentioning

confidence: 99%

Hair color changes and protein damage caused by ultraviolet radiation

Nogueira

Joekes

2004

Journal of Photochemistry and Photobiology B: Biology

130

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Relationship of Melanin Degradation Products to Actual Melanin Content: Application to Human Hair

Cited by 84 publications

References 32 publications

Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries

Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries

Photoaggravation of hair aging

Hair color changes and protein damage caused by ultraviolet radiation

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