Relationship of the single nucleotide polymorphism of the CYP19A1 rs2414098 gene with the risk of endometrioid adenocarcinoma

The aim of the study is to analyze the literature available, to examine bariatric surgery as a treatment for people with metabolic syndrome (a risk factor for atypical endometrial hyperplasia), and to evaluate bariatric surgery significance in reducing endometrial cancer incidence. Materials and Methods. The authors scanned the platforms Springer, Pubmed, IFSO, and Google Scholar using such key words as metabolic syndrome, simple and atypical endometrial hyperplasia, endometrial cancer and bariatric surgery, methods for the metabolic syndrome correction in patients with endometrial cancer, effects of bariatric surgery on endometrial cancer, treatment of metabolic syndrome in patients-at-risk for endometrial cancer. The authors examined the articles published in English and Russian no longer than 10 years ago. Results. Metabolic syndrome is a risk factor for endometrial cancer and comorbidity. It expands the bariatric surgery alternatives for patients with Class 1 and Class 2 obesity.

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Surgical Treatment of Obesity as a Risk Factor for Atypical Hyperplasia and Endometrial Cancer

Ivanov

Parsadanyan

Kasparova

2022

Ulyanovsk Medico-biological Journal

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Relationship of the single nucleotide polymorphism of the CYP19A1 rs2414098 gene with the risk of endometrioid adenocarcinoma

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Surgical Treatment of Obesity as a Risk Factor for Atypical Hyperplasia and Endometrial Cancer

Surgical Treatment of Obesity as a Risk Factor for Atypical Hyperplasia and Endometrial Cancer

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