Relationships among interaction products in hybrids between pigeons and doves, following transfer of genes between species

Abstract

Following the transfer to the common pigeon (Columba livia) of a cellular antigen (Cg) from C. guinea, and to Streptopelia risoria of respective members of the group-8 system from chinensis and senegalensis, new combinations of these two antigenic systems were produced from matings of livia and risoria. The hybrid substances associated with the cells of each of the five new combinations of the cellular antigens were related to each other and to the usual F1-livia/risoria cells but, with the possible exception of two, were definitely differentiated from each other. Cross-reactivities of the reagents for the hybrid substances were also observed, primarily with heterozygotes of the group-8 system of Streptopelia. Evidence is thus provided that the interaction takes place primarily if not entirely between the genes of the C-system of Columba and the group-8 system of Streptopelia.