Relationships among quality of life, severity, and control measures in asthma: An evaluation using factor analysis

Schatz, Michael; Mosen, David M.; Apter, Andrea J.; Zeiger, Robert S.; Vollmer, William M.; Stibolt, Thomas B.; Leong, Albin; Johnson, Michael; Mendoza, Guillermo; Cook, E. Francis

doi:10.1016/j.jaci.2005.02.008

Cited by 91 publications

(94 citation statements)

References 19 publications

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“…(18) Several questionnaires have been developed to assess asthma control, including the ACT, (4) the asthma control questionnaire, (19) the In the present study, we found that the patients with longer duration of disease had better quality of life. A likely explanation for that finding is the learning effect (the development of strategies for coping with the disease).…”

Section: Sgrq (Dependent Variable)mentioning

confidence: 52%

Controle da asma e qualidade de vida em pacientes com asma moderada ou grave

et al. 2011

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Objective: To evaluate the association between degree of asthma control and health-related quality of life in patients with moderate or severe asthma. Methods: This was a descriptive observational study involving 59 outpatients with moderate or severe asthma under treatment at the Asthma Outpatient Clinic of the Federal University of Ceará Walter Cantídio University Hospital, in the city of Fortaleza, Brazil. The patients were evaluated regarding sociodemographic and clinical characteristics, as well as spirometric parameters. The asthma control status was assessed using the asthma control test (ACT), and quality of life was assessed using the Saint George's Respiratory Questionnaire (SGRQ). Results: The mean age of the patients was 55.0 ± 12.4 years, and 76.3% were female. The ACT score showed statistically significant negative correlations with all SGRQ scores: total (r = −0.72); symptoms (r = −0.78); activity (r = −0.67); and impact (r = −0.68). Multiple regression analysis showed that the most robust predictive variables for SGRQ total score were ACT score (coefficient = −3.18; 95% CI: −4.14 to −2.23) and duration of disease (coefficient = −0.29; 95% CI: −0.54 to −0.03). The ACT score also explained the linear variation of the SGRQ domains: symptoms (coefficient = −3.41; 95% CI: −4.45 to −2.37); activity (coefficient = −3.07; 95% CI: −4.57 to −1.57); and impact (coefficient = −2.68; 95% CI: −3.71 to −1.65). Conclusions: The degree of asthma control appears to have a significant impact on health-related quality of life.Keywords: Asthma/prevention and control; Quality of life; Questionnaires. ResumoObjetivo: Avaliar a associação entre o estado de controle da asma e a qualidade de vida relacionada à saúde em pacientes com asma moderada ou grave. Métodos: Estudo descritivo observacional com 59 pacientes portadores de asma moderada ou grave, acompanhados no Ambulatório de Asma do Hospital Universitário Walter Cantídio da Universidade Federal do Ceará, em Fortaleza (CE). Os pacientes foram avaliados quanto a dados sociodemográficos, clínicos e espirométricos. O estado de controle da asma foi avaliado através do asthma control test (ACT) e a qualidade de vida através do Saint George's Respiratory Questionnaire (SGRQ). Resultados: A média de idade dos pacientes foi de 55,0 ± 12,4 anos, e 76,3% eram do sexo feminino. Foram observadas correlações negativas significantes entre os escores do ACT e todos os escores do SGRQ: total (r = −0,72); sintomas (r = −0,78); atividade (r = −0,67); e impactos (r = −0,68). A análise de regressão múltipla mostrou que o escore do SGRQ total teve como variáveis preditivas mais robustas o escore do ACT (coeficiente = −3,18; IC95%: −4,14 a −2,23) e tempo de doença (coeficiente = −0,29; IC95%: −0,54 a −0,03). O escore do ACT também explicou linearmente a variação do SGRQ em seus domínios: sintomas (coeficiente = −3,41 e IC95%: −4,45 a −2,37); atividade (coeficiente = −3,07 e IC95%: −4,57 a −1,57); e impactos (coeficiente = −2,68 e IC95%: −3,71 a −1,65). Conclusões: Na amostra estud...

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Section: Sgrq (Dependent Variable)mentioning

confidence: 52%

Controle da asma e qualidade de vida em pacientes com asma moderada ou grave

et al. 2011

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“…This was unexpected given previous research reporting the relationship between health-related quality of life and asthma severity [16][17][18][19]. We used a general measure of health-related quality of life, while many studies showing an association between health-related quality of life and asthma severity used asthma-specific health-related quality of life instruments such as the Asthma Quality of Life Questionnaire [16][17][18][19]. In addition, asthma severity and asthma control are distinct concepts.…”

Section: Discussionmentioning

confidence: 98%

“…Age (continuous) and sex were also included in the models regardless of statistical associations with the independent and dependent variables because findings from previous research have shown associations with either work-related asthma or health-related quality of life [31][32][33]. Poor quality of life among adults with asthma may be related to asthma severity [16][17][18]34]. Therefore, we examined associations between workrelated asthma and health-related quality of life indicators after stratifying for level of asthma control.…”

Section: Discussionmentioning

confidence: 99%

“…However, research by Ford et al [15] that examined health-related quality of life among adults with asthma found that when compared with adults without asthma, adults with asthma have poorer self-rated health and increased number of physically unhealthy days, mentally unhealthy days, and days with activity limitation. Also, studies on health-related quality of life among individuals with asthma have shown that poor quality of life may be related to asthma severity [16][17][18][19]. Moreover, results of clinically based studies of adults with asthma have shown that both occupational and work-exacerbated asthma are associated with poor quality of life [20,21].…”

Section: Introductionmentioning

confidence: 99%

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Health-related quality of life among adults with work-related asthma in the United States

2012

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Purpose-The objective of this study was to examine health-related quality of life among adults with work-related asthma. Methods-We analyzed 2006-2009 Behavioral RiskFactor Surveillance System Asthma Callback Survey data for ever-employed adults with current asthma from 38 states and District of Columbia. Individuals with work-related asthma had been told by a doctor or other health professional that their asthma was related to any job they ever had. Health-related quality of life indicators included poor self-rated health, impaired physical health, impaired mental health, and activity limitation. We calculated prevalence ratios (PRs) adjusted for age, sex, race/ethnicity, education, income, employment, and health insurance.Results-Of ever-employed adults with current asthma, an estimated 9.0 % had work-related asthma, 26.9 % had poor self-rated health, 20.6 % had impaired physical health, 18.2 % had impaired mental health, and 10.2 % had activity limitation. Individuals with work-related asthma were significantly more likely than those with non-work-related asthma to have poor self-rated health [PR, 1.45; 95 % confidence interval (CI), 1.31-1.60], impaired physical health (PR, 1.60; 95 % CI, 1.42-1.80), impaired mental health (PR, 1.55; 95 % CI, 1.34-1.80), and activity limitation (PR, 2.16; 95 % CI, 1.81-2.56).Conclusions-Future research should examine opportunities to improve health-related quality of life among individuals with work-related asthma.G. E. Knoeller ipb8@cdc.gov. Electronic supplementary material The online version of this article

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“…It has been reported that there is a cyclical interaction between respiratory symptoms in asthma and the likelihood of mood disorders, which limits physical and emotional functioning in people with asthma (25,26). Mental health has a strong role in the control of asthma (27). Mood disorders decrease the efficacy of treatment and increase the recurrence of acute attacks, which further reduces QoL (28).…”

Section: Discussionmentioning

confidence: 99%

Health-related quality of life of patients with asthma: a cross-sectional study in Semnan, Islamic Republic of Iran

Kia

Malek

Ghods

et al. 2017

East Mediterr Health J

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Qualité de vie liée à la santé de patients asthmatiques : étude transversale à Semnan, République islamique d'IranRÉSUMÉ L'asthme peut affecter gravement la qualité de vie des personnes qui en souffrent. Les données sur la qualité de vie des personnes vivant avec l'asthme en République islamique d'Iran sont en nombre limité. La présente étude transversale avait pour objectif d'évaluer la qualité de vie des adultes asthmatiques à Semnan sur la base du SF-36, un questionnaire court d'enquête sur la santé comprenant 36 items. L'effet des caractéristiques socio-démographiques sur les scores de la qualité de vie a été examiné. L'étude incluait un échantillon de commodité de 385 patients externes souffrant d'asthme et s'étant rendus dans une clinique spécialisée pour les maladies pulmonaires entre juin et décembre 2013. Les scores moyens des composantes physiques et mentales étaient de 58,8 (ET 18,3) et 57,3 (ET 17,0) respectivement. L'échantillon de l'étude affichait des scores inférieurs pour la qualité de vie dans tous les domaines par rapport à la population de référence (p < 0,05). Les patients ayant un niveau d'instruction moindre, les habitants urbains, les patients veufs/divorcés et les travailleurs manuels obtenaient des scores de la qualité de vie plus faibles (p < 0,05). Des efforts sont requis pour améliorer la qualité de vie des patients asthmatiques parallèlement à la mise en place de plans précis pour leur prise en charge. This cross-sectional study aimed to evaluate quality of life in adults with asthma in Semnan using the 36-item short form health survey (SF-36). The effect of sociodemographic characteristics on quality of life scores was examined. The study included a convenience sample of 385 outpatients with asthma attending a pulmonary clinic from June to December 2013. The mean physical and mental component scores were 58.8 (SD 18.3) and 57.3 (SD 17.0) respectively. The study sample had lower quality of life scores in all the fields than the reference population (P < 0.05). Patients with lower education, urban residents, widowed/divorced patients and manual workers had lower quality of life scores (P < 0.05). Efforts are needed to improve the quality of life of people with asthma in parallel with precise management plans. ‫اإلسالمية‬ ‫إيران‬ ‫مجهورية‬ ‫سيمنان،‬‫املتوسط‬ ‫لرشق‬ ‫الصحية‬ ‫املجلة‬ ‫العرشون‬ ‫و‬ ‫الثالث‬ ‫املجلد‬ ‫السابع‬ ‫العدد‬ 501

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Relationships among quality of life, severity, and control measures in asthma: An evaluation using factor analysis

Cited by 91 publications

References 19 publications

Controle da asma e qualidade de vida em pacientes com asma moderada ou grave

Controle da asma e qualidade de vida em pacientes com asma moderada ou grave

Health-related quality of life among adults with work-related asthma in the United States

Health-related quality of life of patients with asthma: a cross-sectional study in Semnan, Islamic Republic of Iran

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