Relationships of obesity and diabetes mellitus to other primary cancers in surgically treated gastric cancer patients

Takeuchi, Daisuke; Koide, Naoki; Komatsu, Daisuke; Okumura, Motohiro; Suzuki, Akira; Miyagawa, Shinichi

doi:10.1016/j.ijsu.2014.04.012

Cited by 10 publications

(9 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Green et al [ 13 ] reported that an OPM was observed in approximately 8% of advanced GC patients and 32% of early GC patients. Our previous study also showed that OPM was observed in 25% of GC patients [ 14 ]. In the present study, the incidence of OPM was 21.5%.…”

Section: Discussionmentioning

confidence: 81%

“…On the other hand, the presence of a preoperative OPM was an independent prognostic factor for OS. Our previous study also showed that GC patients with synchronous OPMs had a worse outcome after surgery than those without it [ 14 ]. Furthermore, Kim et al [ 6 ] regarded that the presence of synchronous and metachronous OPMs negatively affected the clinical outcome of GC survivors.…”

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

High incidence of other primary malignancies in patients with synchronous multiple gastric cancers “a multi-center retrospective cohort study”

Takeuchi

Koide²,

Suzuki

et al. 2018

Oncotarget

Self Cite

View full text Add to dashboard Cite

This study evaluated the relationship between synchronous multiple gastric cancer and other primary malignancies. During 2002–2013, 1094 consecutive surgically treated gastric cancer patients were enrolled. Preoperatively, we performed total colonoscopy and whole-body computed tomography. When malignancies in other organs were suspected, detailed organ-specific examinations were performed. Synchronous multiple gastric cancer occurred in 102 patients (9.3%)which was frequently observed in patients with preoperative other primary malignancies (p < 0.001). Preoperative other primary malignancy was an independent risk factor for synchronous multiple gastric cancer (p = 0.001; hazard ratio: 2.145, 95% confidence interval: 1.354–3.399) and an independent prognostic factor of overall survival in patients undergoing gastrectomy with curative intent (p = 0.021; hazard ratio: 1.481, 95% confidence interval: 1.060–2.070). Thus, patients with preoperative other primary malignancies have a high risk of synchronous multiple gastric cancer. Careful preoperative examination is recommended to improve survival.

show abstract

Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 97%

High incidence of other primary malignancies in patients with synchronous multiple gastric cancers “a multi-center retrospective cohort study”

Takeuchi

Koide²,

Suzuki

et al. 2018

Oncotarget

Self Cite

View full text Add to dashboard Cite

show abstract

“…The rarest combination was that of CRC and skin cancer, which was found in only 1 of 117 patients with MPMs (3). For patients with gastric cancer, Takeuchi et al (13) reported that MPMs were observed in 109 patients (25.1%): 40 (9.2%) with synchronous and 76 (18.2%) with metachronous MPMs. The most common malignancy was colorectal cancer (22.8%).…”

Section: Discussionmentioning

confidence: 99%

Multiple primary malignancies of six organs in a Japanese male patient: A case report

et al. 2019

View full text Add to dashboard Cite

As a result of recent advances in diagnostic techniques and treatment modalities, the number of patients diagnosed with multiple primary malignancies has been increasing. We report the case of a 79-year-old male with multiple primary malignancies of three histological types in six different organs: Stomach, prostate, colon, urinary bladder, facial skin and pancreas, in chronological order. The first malignancy was upper gastric cancer diagnosed in 1998. The second and third malignancies were prostate cancer and ascending colon cancer, which were diagnosed in 2010. The fourth malignancy was bladder cancer diagnosed in 2011. The fifth and sixth malignancies were squamous cell skin cancer of the right cheek and intraductal papillary mucinous carcinoma (IPMC), respectively, diagnosed in 2014. The gastric cancer, colon cancer, bladder cancer, skin cancer and IPMC were surgically resected. The prostate cancer was treated by anti-androgen therapy. The patient died of local recurrence of IPMC in August 2016. Although multiple primary malignancies are not uncommon, diagnosis of six primary malignancies in a single patient, as reported in the present study, is extremely rare. It is important to understand the characteristics of multiple primary malignancies in order to administer suitable treatment and determine relevant follow-up plans for patients with cancer.

show abstract

“…Periodic cancer screening and radical resection with regional lymph node dissection have significantly improved the clinical outcomes of patients with GC [3,5]. However, the synchronous presence of another primary malignancy negatively affected the clinical outcomes of GC survivors [5,6]. Kim et al have hypothesized that synchronous cancers prevented the proper treatment of GC5.…”

Section: Discussionmentioning

confidence: 99%

A case of synchronous advanced gastric cancer and locally advanced prostate cancer with combined laparoscopic and robotic surgery: A case report

Imagami

Takayama

Hattori

et al. 2019

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Highlights The optimal management for synchronous advanced cancer remains controversial. Multidisciplinary treatment strategies are important for synchronous advanced cancer. Combined laparoscopic and robotic surgery allows minimally invasive resection. Simultaneous endoscopic surgery is recommended for synchronous advanced cancer.

show abstract

Relationships of obesity and diabetes mellitus to other primary cancers in surgically treated gastric cancer patients

Abstract: There is a need to be aware of the possibility of OPC in GC patients with DM/obesity. They should undergo intensive screening for OPC before and after gastrectomy.

Cited by 10 publications

References 37 publications

High incidence of other primary malignancies in patients with synchronous multiple gastric cancers “a multi-center retrospective cohort study”

High incidence of other primary malignancies in patients with synchronous multiple gastric cancers “a multi-center retrospective cohort study”

Multiple primary malignancies of six organs in a Japanese male patient: A case report

A case of synchronous advanced gastric cancer and locally advanced prostate cancer with combined laparoscopic and robotic surgery: A case report

Contact Info

Product

Resources

About