Relative frequencies of DRB1∗11 alleles and their DRB3 associations in five major population groups in a United States bone marrow registry

HLA-DRB1 and -DRB3 allele frequencies and haplotypic associations in Koreans

“…DRB1*0301-DRB3*0101, a rare haplotype in Koreans, is very common in Caucasoids or African Amer- icans [7,8]. DRB1*1101-DRB3*0101 and DRB1*1401-DRB3*0101 are present in Caucasoids or African Americans at a very low frequency [9,11]. DRB1*1106-DRB3*0202 and DRB1*1404-DRB3*0101 are present in Thais or other Asian populations [11,14].…”

“…There are considerable racial differences in the distribution of DRB1-associated DRB3 alleles [5][6][7][8][9][10][11][12][13][14]. In African and Asian populations, DRB1-DRB3 linkages remarkably different from Caucasians have been reported [5,6,12,14].…”

Strategies and technical challenges in allele level Class II typing in 2578 bone marrow transplantation donor–recipient pairs

“…However, several lines of evidence suggest these new alleles have had little effect on our study. First, alleles discovered at these loci between 1994 and the present have been generally uncommon or largely found in a specific population [31][32][33]. This study population was predominately white and biased toward more common alleles and haplotypes.…”

HLA-DRB1*1101 allele confer protection for Multiple Sclerosis disease in Cuban population

“…DRB1*1101 has been described as the predominant allele, while HLA DRB1*1104 is the second most frequent allele, as stated by a previous study that included Caucasian, Asian/Pacific Islanders, Hispanics and Native Americans. 31 Even more, HLA-DRB1*1101 is part of certain allele groups defined for their association to MS risk , 7,32 which is formed by the alleles DRB1*03, DRB1*14, DRB1*07 and DRB1*11. However in the present study this allele was associated to disease protection, a result that corresponds to reports from others authors 33 which have found that HLA-DRB1*14 and HLA-DRB1*11 bearing haplotypes are protective with OR 0.75 and 0.55 respectively.…”