Relative toxicity of the components of the original formulation of Roundup® to five North American anurans

Moore, Lindsay J.; Fuentes, Latice; Rodgers, John H.; Bowerman, William W.; Yarrow, Greg; Chao, Wayne Y.; Bridges, William C.

doi:10.1016/j.ecoenv.2011.11.025

Cited by 108 publications

(80 citation statements)

References 19 publications

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“…Several studies have reported that the toxicity glyphosate-based herbicides to organisms is largely due to surfactants in the mixture. Specifically, glyphosate formulations containing polyethoxylated tallow amine were more toxic than pure active substance or some formulations with other surfactants (Howe et al 2004, Moore et al 2012, Uren-Webster et al 2014). However, the results obtained by Sihtmäe et al (2013) show the different effect of two glyphosate formulations (Roundup Quick and Roundup Max) on the soil bacteria that are the main biological detoxifiers of glyphosate in soil.…”

mentioning

confidence: 99%

Response of soil phosphatases to glyphosate and its formulations - Roundup (laboratory conditions)

Płatkowski¹,

Telesiński²

2016

PLANT SOIL ENVIRON

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confidence: 99%

Response of soil phosphatases to glyphosate and its formulations - Roundup (laboratory conditions)

Płatkowski¹,

Telesiński²

2016

PLANT SOIL ENVIRON

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“…de glifosato/L, se encuentran dentro del rango reportado para otras especies expuestas a diferentes presentaciones comerciales de glifosato (Edginton et al, 2004;Relyea y Jones, 2009;Moore et al, 2012). Particularmente, los intervalos de confianza de los CL 50 encontrados para el Roundup ® Activo no se diferenciaron significantemente con los reportados por Bernal et al, (2009a) para la mezcla del glifosato (Glyphos ® ) y el Cosmo-Flux ® 411F, a excepción de H. crepitans que resultó ser la especie más sensible, y de los hallados por Triana et al, (2013) en embriones de estas especies expuestas al Roundup ® Activo.…”

Section: Discussionunclassified

Evaluación De La Toxicidad De Dos Agroquimicos, Roundup® Activo Y Cosmo-Flux®411f, en Renacuajos De Anuros Colombianos

Muñoz¹,

Velásquez²,

Bernal³

2014

Acta biol. Colomb.

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RESUMEN El Roundup® Activo es un herbicida elaborado a base de glifosato ampliamente utilizado en Colombia para el control de malezas. Sin embargo, para su aplicación requiere ser mezclado con un coadyuvante que facilite su acción, tal como el Cosmo-Flux ® 411F el cual mejora la adherencia y fijación del herbicida en las hojas de las plantas. El objetivo de este estudio fue determinar la concentración letal media (CL 50 ) y algunos efectos subletales (cambios en el tamaño corporal y en el desempeño natatorio) del Roundup ® Activo y del Cosmo-Flux ® 411F en renacuajos de cuatro especies de anuros colombianos expuestos bajo condiciones controladas de laboratorio y en microcosmos. La especie más sensible a la exposición del Roundup ® Activo fue Hypsiboas crepitans (Laboratorio: CL 50 = 1414 µg a.e. de glifosato/L y microcosmos: CL 50 = 4 kg a.e. de glifosato/ha) y para el Cosmo-Flux Palabras clave: anfibios, CL 50 , efectos subletales, glifosato. ABSTRACT Roundup® Active is an herbicide based on glyphosate widely used in Colombia for control of illicit crops and weeds. However, it must be mixed with an adjuvant that facilitates its action, such as the Cosmo-Flux ® 411F which improves the adhesion and fixation of the herbicide into the leaves of the plants. The aim of this study was to determine the median lethal concentration (LC 50 ) and some sublethal effects (changes in body size and swimming performance) of the Roundup ® Active and the Cosmo-Flux ® 411F to tadpoles of four Colombian anuran species exposed under laboratory and microcosm conditions. The most sensitive species to exposure of Roundup ® Active was Hypsiboas crepitans (Laboratory: LC 50 = 1414 µg a.e. glyphosate/L; microcosm: LC 50 = 4 kg a.e. glyphosate/ ha), and for Cosmo-Flux ® 411F was Rhinella humboldti (Laboratory: LC 50 = 319 mg/L; microcosm: LC 50 = 632.3 L/ha). In laboratory and microcosms, Roundup ® Active did not alter the tadpole body size nor the swimming performance, while the Cosmo-Flux ® 411F generated changes in the body size but not in the swimming performance. Comparing the LC 50 of the two agrochemicals with respect to concentrations used in field, the Roundup ® Active exerted a moderate risk whereas the Cosmo-Flux ® 411F was not lethal. In addition, the Roundup ® Active was notably more toxic than the Cosmo-Flux ® 411F.

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“…Polyoxyethylene amine (POEA) and polyethoxylated tallowamine (POE-15) are commonly used surfactants in Roundup formulations, and have been shown to contribute significantly to the toxicity of Roundup formulations Mesnage et al 2012;Moore et al 2012). However, glyphosate alone has also been shown to interfere with molecular mechanisms that regulate early development in frogs and chicken, with deformities of embryos as a consequence and the retinoic acid signaling pathway as the affected mediator (Paganelli et al 2010).…”

Section: Toxicity and Health Relevance Of Pesticide/glyphosate Residuesmentioning

confidence: 99%

Are Ready for Market Genetically Modified, Conventional and Organic Soybeans Substantially Equivalent as Food and Feed?

Bøhn

Cuhra

Traavik

et al. 2016

Genetically Modified Organisms in Food

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SummaryImportant compositional elements, including residues of herbicides, were investigated in commercial soy varieties grown within the same geographical area. These included genetically modified, conventional and organic soybeans. Feed made from these soybeans was subsequently fed to the model organism Daphnia magna, while measuring the fitness performance (survival, growth and reproduction) during the full life cycle of the animals. The conventional and organic samples contained no residues of glyphosate or its degradation product AMPA, but the GM-soy contained such residues, averaging 9.0 mg/kg. The fitness of D. magna fed organic soybeans was superior to that of animals fed GM soybeans, while animals fed conventional soybeans was intermediate. There were large fitness differences for D. magna fed raw soybeans, but smaller with heat-treated soy. In conclusion: herbicides associated with GM soybeans (and/or other factors associated with these crops) may compromise food and feed quality.

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Relative toxicity of the components of the original formulation of Roundup® to five North American anurans

Cited by 108 publications

References 19 publications

Response of soil phosphatases to glyphosate and its formulations - Roundup (laboratory conditions)

Response of soil phosphatases to glyphosate and its formulations - Roundup (laboratory conditions)

Evaluación De La Toxicidad De Dos Agroquimicos, Roundup® Activo Y Cosmo-Flux®411f, en Renacuajos De Anuros Colombianos

Are Ready for Market Genetically Modified, Conventional and Organic Soybeans Substantially Equivalent as Food and Feed?

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