Relaxation of DNA on a supported lipid membrane

J Polym Sci B Polym Phys

et al. 2018

The coil-globule transition and dynamics of a lattice self-avoiding bond fluctuation polymer chain confined in slit are studied by Monte Carlo simulations. The coil-globule transition temperature of polymer chain is increased at intermediate slit height H (H $ R G0 with R G0 the radius of gyration of polymer in dilute solution) due to the squeeze of the polymer in the repulsive slit, but it is decreased by surface attraction as the polymer is extended along the surface. We have compared the difference between the rotational relaxation time s R for the reorientation of end-to-end vector and the relaxation time s for the polymer diffusing over a distance of the size of polymer. We find that s R is clearly distinct from s as they have different scaling exponents in their slit height-dependent behaviors s R $ H 2aR and s $ H 2a for the polymer in the extended coil state, that is, a R > a. And both exponents increase with an increase in the intrapolymer attraction and surface attraction. However, these scaling relations are destroyed by strong surface attraction when the polymer is adsorbed on surfaces.

A_{| |} = \frac{{(L_{1}^{2} - L_{2}^{2})}^{2}}{{(L_{1}^{2} + L_{2}^{2})}^{2}}

, in which

L_{1}^{2}

and

L_{2}^{2}

are two eigenvalues of a 2D gyration tensor:

S_{x y} = \frac{1}{N} \sum_{i = 1}^{N} s_{i} s_{i}^{T} = true(\begin{matrix} S_{x x} & S_{x y} \\ S_{x y} & S_{y y} \end{matrix} true),

where

s_{i} = col (x_{i}, y_{i})

Section: Resultsmentioning

confidence: 99%

Study on the coil–globule transition and dynamics of polymer chain confined in slit

Luo

Tian

J Polym Sci B Polym Phys

et al. 2018

“…It was found that the adsorption of polymers also relates to DNA packaging in viruses, and immobilization of enzyme . The adsorption of polymers on solid surface or membrane is an important research topic and has attracted extensive attention from experiments, theory, and computation simulations . Experiments and simulation studies on polymer adsorption showed that polymers would change their size and shape after adsorption …”

Section: Introductionmentioning

confidence: 99%

“…The adsorption transitions were well studied for both collapsed and extended conformations . Polymer conformation is changed during the adsorption . For both collapsed and extended conformations, the statistical size parallel to the surface is increased obviously at E PS >

E_{PS}^{CAP}

.…”

Section: Introductionmentioning

confidence: 99%

Simulation study on the coil-globule transition of adsorbed polymers

J. Polym. Sci. Part B: Polym. Phys.

Wang

et al. 2016

Coil‐globule transition of adsorbed polymers on attractive surface is simulated by using dynamic Monte Carlo simulation. The effect of surface attraction strength EPS and intrachain attraction strength EPP on polymer phases is investigated. The coil‐globule transition point is dependent on EPS, while the globule conformation is dependent on both EPS and EPP. At small EPS, the conformation of adsorbed polymer is three‐dimensional layer structure. While at large EPS, the conformation of adsorbed polymer is roughly two‐dimensional (2D) at EPP = 0, and we observe a 2D coil‐globule transition at E*PP and a layer‐forming transition from 2D conformation to three‐dimensional layer structure at E*PP,L > E*PP. The layer‐forming transition point E*PP,L increases with EPS as E*PP,L = EPS − 1.4. In addition, we find that the adsorption suppresses the coil‐globule transition, i.e., the coil‐globule transition point E*PP increases with the increase in EPS. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2016, 54, 2359–2367

“…Adsorption of flexible polymers can significantly and permanently modify the properties of surfaces1. Simultaneously the attractive surface also changes the conformational and dynamic properties of polymers234. The properties of adsorbed polymers play important roles in many chemical and biological applications1567, such as polymer nanocomposite materials8, compatibilization by copolymers91011, colloid stabilization by polymeric surfactants1213, coating and lubrication14, and DNA segregating in bacteria15 and packaging in viruses16.…”

mentioning

confidence: 99%

“…The properties of adsorbed polymers play important roles in many chemical and biological applications1567, such as polymer nanocomposite materials8, compatibilization by copolymers91011, colloid stabilization by polymeric surfactants1213, coating and lubrication14, and DNA segregating in bacteria15 and packaging in viruses16. The adsorption of polymers on surfaces/interfaces and the dynamical properties of adsorbed polymers have motivated extensive studies in experiment3171819202122232425, theory and simulation24262728293031323334353637383940414243444546474849.…”

mentioning

confidence: 99%

Dynamics of adsorbed polymers on attractive homogeneous surfaces

Luo

2016

Sci Rep

Dynamic behaviors of polymer chains adsorbed on an attractive, homogeneous surface are studied by using dynamic Monte Carlo simulations. The translational diffusion coefficient Dxy parallel to the surface decreases as the intra-polymer attraction strength EPP or the polymer-surface attraction strength EPS increases. The rotational relaxation time τR increases with EPS, but the dependence of τR on EPP is dependent on the adsorption state of the polymer. We find that τR decreases with increasing EPP for a partially adsorbed polymer but it increases with EPP for a fully adsorbed polymer. Scaling relations Dxy ~ N−α and τR ~ Nβ are found for long polymers. The scaling exponent α is independent of EPS for long polymers but increases with EPP from α = 1.06 at EPP = 0. While β ≈ 2.7 is also roughly independent of EPS for the adsorbed polymer at EPP = 0, but β increases with EPS at EPP > 0. Moreover, we find that β always decreases with increasing EPP. Our results reveal different effects of the attractive surface on the diffusion and rotation of adsorbed polymers.