Relevance of Skip Metastases for Squamous Cell Carcinoma of the Oral Tongue and the Floor of the Mouth

Abstract

C-4.

Proliferative verrucous leukoplakia, squamous cell carcinoma and axillary metastasis

“…Clearly, PVL is resistant to the available treatment modalities, such as cold knife surgery, CO2.laser evaporation, laser surgery, chemotherapy, radiotherapy and presents frequent recurrences (8). Distant metastases from head and neck SCC are relatively common, mainly after recurrence of local or regional disease, but metastases from the upper aerodigestive tract to the axillary lymph nodes is an unusual event (12,14). The metastases drainage way can be suggested mainly by location, size of the primary tumor and regional lymph nodal control (11).…”

“…Eventually, metastasis can follow an unpredictable pattern and involve unexpected lymph nodes such as contralateral cervical lymph nodes, low jugular-carotid lymph nodal chain and even axillary lymph nodes (12,13). There are few reports published in the English-language literature about axillary metastasis from head and neck squamous cell carcinoma (HNSCC) and fewer from oral SCC (14). This paper presents the case of a 64-yearold female patient who was diagnosed with PVL and developed five oral SCC and later an axillary lymph node metastasis.…”

Current Concept of Selective Nek Dissection

“…An ideal neck dissection for clinically N0 neck should remove all the lymph node groups, which potentially harbor occult metastases while preserving the non-lymphatic structures along with the lymph node groups that are unlikely to contain occult metastases. It has been demonstrated that level V is rarely involved in oral cavity cancers (Dias, 2006). Furthermore, these rare metastases to level V occur only when other levels are involved and isolated metastasis to level V never happens (Dias, 2006).…”

“…It has been demonstrated that level V is rarely involved in oral cavity cancers (Dias, 2006). Furthermore, these rare metastases to level V occur only when other levels are involved and isolated metastasis to level V never happens (Dias, 2006). It has been well-known that levels I,II and III are the most frequently involved levels in oral cavity cancers and removal of these lymph node groups through a level I-III neck dissection (supraomohyoid neck dissection) has been the standard treatment of clinically N0 oral cavity cancer.…”

A valuable system with high specificity for evaluating both metastasis and prognosis of oral squamous cell carcinoma

“…The goal of surgical treatment is to prevent local and regional recurrence and instant metastasis to the regional lymph node so as to increase the survival rate [1][2][3] . If the potential of local invasion, the status of regional lymph nodes metastasis and prognosis of SCC were recognized before an operation, it would increase the options in determining the best therapy methods for the patients.…”