Relevanz des Meniskusverlustes für die Arthroseprogression und Therapieoption bei bereits bestehender Früharthrose

Patsch, Christian; Dirisamer, Florian; Schewe, B.

doi:10.1007/s00132-021-04101-z

Cited by 4 publications

(3 citation statements)

References 33 publications

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“…Meniscus lesions has been identi ed as a potential cause of knee ROA and may indicate the early onset of OA [30]. There are many causes of meniscus injury, and the relationship between these causes and OA has been studied by many scholars, but the mechanism remains to be clari ed.…”

Section: Discussionmentioning

confidence: 99%

Quantitative measures of the medial and lateral novel meniscus parameters predict incident radiographic knee osteoarthritis: the Osteoarthritis Initiative

Liu

et al. 2023

Preprint

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Background: To determine whether novel meniscus parameters are predictive of incident radiographic knee osteoarthritis (ROA) over four years in the Osteoarthritis Initiative (OAI) study. Methods: Participants were extracted from the Osteoarthritis Initiative (OAI) study. 178 knees (from 176 patients ) with incident ROA (Kellgren Lawrence Grade (KLG) 0 or 1 at baseline (BL), developing KLG 2 or greater by year 4) were matched one-to-one by gender, age and radiographic status with 178 control knees (from 178 patients) not developing incident ROA. Novel meniscal parameters were measured on coronal T2-weighted turbo spin echo (TSE) MRI. Conditional logistic regression analyses were used to assess the risk of incident ROAassociated with novel meniscus parameters after adjustment for covariates. Sensitivity analysis was performed for P0 (time to visit when ROA was found on the radiographs) , P1 (1 year prior to P0) and baseline (enrollment period) ROA incidence. Results: Intra-class and inter-class reliabilities of measurement of novel parameters were excellent (≥0.89). Baseline meniscus measurement parameters included the mean of MLD [mean(MLD)], the mean of RMLD [mean(RMLD)] and the mean of TPW[Mean(TPW)]. Baseline Mean(MLD) and Mean(RMLD) [Mean(MLD), Mean(RMLD)] [Adjusted OR, 95%CI: 1.11(1.07 to 1.16) and 1.13(1.09 to 1.17), respectively] were associated with incident ROA during 4 years, but mean value of tibial plateau width [Mean(TPW)] [Adjusted OR, 95%CI: 0.98(0.94 to 1.02)] was not associated with incident ROA during 4 years. At baseline, Mean (MLD) and Mean (RMLD) were significantly different between case and control groups. While P1 and P0 [Mean(TPW)] were not associated with incident ROA risk, other measures of P1 and P0 were significantly positivelyassociated with incident ROA risk. Conclusions: The novel method of measuring meniscus novel parameters on MRI is reproducible. Compared with the control group, Mean(MLD) and Mean(RMLD) at baseline, P1 and P0 periods are higher in the case group than in the control group and the measurement differed significantly among the groups. These novel meniscus parameters alterations could be an important imaging biomarker to predict the occurrence of ROA.

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Section: Discussionmentioning

confidence: 99%

Quantitative measures of the medial and lateral novel meniscus parameters predict incident radiographic knee osteoarthritis: the Osteoarthritis Initiative

Liu

et al. 2023

Preprint

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“…The meniscus is an important component of the knee joint, and its main functions are to absorb shock, transmit load, lubricate the joint, and improve the matching degree of the femur and tibia ( Lau et al, 2018 ; Kani et al, 2021 ; Patsch et al, 2021 ). The biomechanical changes following meniscal tears and surgery could lead to osteoarthritis ( Lau et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Biomechanical effects of the medial meniscus horizontal tear and the resection strategy on the rabbit knee joint under resting state: finite element analysis

Xue

Mao

Zhu

et al. 2023

Front. Bioeng. Biotechnol.

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The biomechanical changes following meniscal tears and surgery could lead to or accelerate the occurrence of osteoarthritis. The aim of this study was to investigate the biomechanical effects of horizontal meniscal tears and different resection strategies on a rabbit knee joint by finite element analysis and to provide reference for animal experiments and clinical research. Magnetic resonance images of a male rabbit knee joint were used to establish a finite element model with intact menisci under resting state. A medial meniscal horizontal tear was set involving 2/3 width of a meniscus. Seven models were finally established, including intact medial meniscus (IMM), horizontal tear of the medial meniscus (HTMM), superior leaf partial meniscectomy (SLPM), inferior leaf partial meniscectomy (ILPM), double-leaf partial meniscectomy (DLPM), subtotal meniscectomy (STM), and total meniscectomy (TTM). The axial load transmitted from femoral cartilage to menisci and tibial cartilage, the maximum von Mises stress and the maximum contact pressure on the menisci and cartilages, the contact area between cartilage to menisci and cartilage to cartilage, and absolute value of the meniscal displacement were analyzed and evaluated. The results showed that the HTMM had little effect on the medial tibial cartilage. After the HTMM, the axial load, maximum von Mises stress and maximum contact pressure on the medial tibial cartilage increased 1.6%, 1.2%, and 1.4%, compared with the IMM. Among different meniscectomy strategies, the axial load and the maximum von Mises stress on the medial menisci varied greatly. After the HTMM, SLPM, ILPM, DLPM, and STM, the axial load on medial menisci decreased 11.4%, 42.2%, 35.4% 48.7%, and 97.0%, respectively; the maximum von Mises stress on medial menisci increased 53.9%, 62.6%, 156.5%, and 65.5%, respectively, and the STM decreased 57.8%, compared to IMM. The radial displacement of the middle body of the medial meniscal was larger than any other part in all the models. The HTMM led to few biomechanical changes in the rabbit knee joint. The SLPM showed minimal effect on joint stress among all resection strategies. It is recommended to preserve the posterior root and the remaining peripheral edge of the meniscus during surgery for an HTMM.

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“…al., 2018;Kani et al, 2021;Patsch et al, 2021). The biomechanical changes following meniscal tears and surgery could lead to osteoarthritis(Lau et al, 2018).…”

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confidence: 99%

Animal Biomechanics: Application of the Biomedical Engineering to the Veterinary Sciences for the Animal Healthcare

Malvè,

Di Giancamillo,

Fernández-Parra

et al. 2024

Frontiers Research Topics

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Frontiers is more than just an open access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge. Frontiers provides immediate and permanent online open access to all its publications, but this alone is not enough to realize our grand goals. Frontiers journal seriesThe Frontiers journal series is a multi-tier and interdisciplinary set of openaccess, online journals, promising a paradigm shift from the current review, selection and dissemination processes in academic publishing. All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service to the scholarly community. At the same time, the Frontiers journal series operates on a revolutionary invention, the tiered publishing system, initially addressing specific communities of scholars, and gradually climbing up to broader public understanding, thus serving the interests of the lay society, too. Dedication to qualityEach Frontiers article is a landmark of the highest quality, thanks to genuinely collaborative interactions between authors and review editors, who include some of the world's best academicians. Research must be certified by peers before entering a stream of knowledge that may eventually reach the public -and shape society; therefore, Frontiers only applies the most rigorous and unbiased reviews. Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new generation. What are Frontiers Research Topics?Frontiers Research Topics are very popular trademarks of the Frontiers journals series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area.

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Relevanz des Meniskusverlustes für die Arthroseprogression und Therapieoption bei bereits bestehender Früharthrose

Cited by 4 publications

References 33 publications

Quantitative measures of the medial and lateral novel meniscus parameters predict incident radiographic knee osteoarthritis: the Osteoarthritis Initiative

Quantitative measures of the medial and lateral novel meniscus parameters predict incident radiographic knee osteoarthritis: the Osteoarthritis Initiative

Biomechanical effects of the medial meniscus horizontal tear and the resection strategy on the rabbit knee joint under resting state: finite element analysis

Animal Biomechanics: Application of the Biomedical Engineering to the Veterinary Sciences for the Animal Healthcare

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