Reliability and Validity of the Korean Translation of Quantitative Checklist for Autism in Toddlers: A Preliminary Study

Park, Subin; Won, Eun-Kyung; Lee, Ji Hyun; Yoon, Soyoung; Park, Eun Jin; Kim, Yeni

doi:10.5765/jkacap.2018.29.2.80

Cited by 9 publications

(6 citation statements)

References 6 publications

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“…Another issue is that that the gender breakdown in the case derivation (N = 7: F/M 0:7) and validation (N = 6: F/M 1:5) sample lacks female participants in one case and only has one in the other. Considering that we were screening in general population Controls, and then in a DD sample, this derivation sample falls in line with previous research with small samples or who didn't provide a derivation/validation analysis for this subgroup, with our overall sample size (N = 287) being larger than those studies (Devescovi et al, 2020;Park et al, 2018;Raza et al, 2019;Wong et al, 2014). We do acknowledge that his might be a source of bias, but the results stemming from this analysis replicate the ones reported in Allison et al (2012Allison et al ( , 2008.…”

Section: Discussionsupporting

confidence: 67%

Autism screening and conditional cash transfers in Chile: Using the Quantitative Checklist (Q-CHAT) for early autism detection in a low resource setting

Román-Urrestarazu

Yáñez

López-Garí

et al. 2020

Autism

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Diagnosis of Autism Spectrum Conditions (ASC) can be an extended procedure since ASC tend to both vary greatly across individual symptoms and diagnostic pathways with serious challenges to opportune access and diagnosis in low resource settings. We adapted the Q-CHAT-25 for use in a routine health check-ups programme at Chilean primary health clinics by developing a 10-item version of this questionnaire recruiting n = 287 (F: 112/M: 175) participants (Controls: n = 125, F: 58/M: 67; Developmental Delay: n = 149, F: 53/M: 96; Autism Spectrum Conditions: n = 13, F: 1/M: 12). Our findings show that the Q-CHAT-10 can be successfully applied in health-check programmes. The results for the Q-CHAT-10 show high internal consistency (Cronbach’s α: 0.85) and good overall performance, significantly correlating (r = 0.79, p < 0.0001) with the Q-CHAT-25. The Q-CHAT-10 had a sensitivity of 92.86% and a specificity of 76.86% in the Developmental Delay sample. The positive predictive value was 48% with a positive likelihood ratio of 4.01 and a negative likelihood ratio of 0.09 with a post-test probability of disease of 19%. This study provides evidence that the implementation of Autism Spectrum Condition screening programmes using the Q-CHAT-10 is a cost-effective measure that improves diagnosis of Autism Spectrum Conditions in those participating in conditional cash transfer programmes in low- and middle-income countries or low resource setting in high income countries. Lay abstract Getting a diagnosis of autism can take long, because autism is different across people, but also because it depends on the way it gets diagnosed. This is especially important in poorer countries or in the case of poor people living in wealthier countries that have significant groups of disadvantaged communities. We adapted a 10-item version of the Q-CHAT-25 questionnaire for use in routine health check-ups programme in Chile and recruited 287 participants under the age of three divided into three groups: Controls (125), Developmental Delay (149) and Autism Spectrum Condition (13). Our results show that a short questionnaire for autism screening can be successfully applied in a health-check programme in poor resource settings. Our results show that our questionnaire had good overall performance, not different to its longer version, the Q-CHAT-25. Our questionnaire was autism specific, with good sensitivity and reliability, and is suitable to be used in a screening setting. This study provides evidence that the implementation of Autism Spectrum Condition screening programmes using the Q-CHAT-10 provides value for money and improves diagnosis of Autism Spectrum Condition in those participating in routine health check-up programmes in developing countries or poor areas of wealthy countries.

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Section: Discussionsupporting

confidence: 67%

Autism screening and conditional cash transfers in Chile: Using the Quantitative Checklist (Q-CHAT) for early autism detection in a low resource setting

Román-Urrestarazu

Yáñez

López-Garí

et al. 2020

Autism

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“…Several papers presented studies in which translated versions of the Q-CHAT were used: Spanish [ 25 ], Persian [ 26 ], and Korean [ 27 ]. Translations into other languages also exist [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

“…However, the results of other studies did not support the existence of differences between preschool boys and girls with suspected autism [ 38 ] or found a pattern of overall similarities with few gender differences [ 39 ]. Several studies that used the Q-CHAT reported gender differences with boys scoring higher than girls [ 14 , 40 , 41 ], while some other studies did not demonstrate such differences [ 27 ]. The latter may suggest that girls and boys are less dissimilar than previously thought, but an alternative interpretation could be that currently available instruments under-identify difficulties among girls [ 38 ].…”

Section: Introductionmentioning

confidence: 99%

Symptoms of Autism Spectrum Disorders Measured by the Qualitative Checklist for Autism in Toddlers in a Large Sample of Polish Toddlers

Niedźwiecka

Pisula

2022

IJERPH

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This study aimed to assess some early symptoms of autism spectrum disorders (ASD) measured by a screening tool developed for an early detection of ASD. We investigated if the early symptoms were associated with toddlers’ age, gender or ASD familial risk status. We used the Polish version of the Quantitative Checklist for Autism in Toddlers (Q-CHAT) to assess 1024 children aged 16 to 36 months. The sample included four groups of participants: typically developing toddlers, toddlers with parent-reported ASD-specific concerns, toddlers at risk for autism due to having an older sibling with ASD, and toddlers with a developmental delay. We found that mean Q-CHAT scores were significantly higher in boys than in girls. We did not find any associations between Q-CHAT scores and age. We observed that toddlers with a familial risk for ASD and those with a developmental delay scored significantly higher than controls. We collated these results with previous studies that used the Q-CHAT and other instruments.

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“…The Q-CHAT is a 25-item questionnaire with each item rated by the parents from 0-4. It has been validated for use in multiple countries (Magiati et al, 2015;Mohammadian et al, 2015;Park et al, 2018;Ruta et al, 2019;Wong et al, 2014), and has been reported to show a positive predictive value of 28% for a future ASD diagnosis (using screening at two timepoints) (Allison et al, 2021). Some factors previously reported to increase the likelihood of an autism diagnosis have also been shown to correlate with autism traits at age 18 months -for example, sex (with males scoring higher than females) (Allison et al, 2008;Auyeung et al, 2012;Guthrie et al, 2019) or preterm birth (Gray et al, 2015;Wong et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical, socio-demographic, and parental correlates of early autism traits in a community cohort

Gale‐Grant

Chew

Falconer

et al. 2022

Preprint

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Importance: Autism traits typically emerge between the ages of 1 and 2. It is not known if experiences which increase the likelihood of childhood autism are related to early trait emergence, or if other exposures are more important. Identifying factors linked to toddler autism traits may improve our understanding of the mechanisms underlying atypical neurodevelopment. Objective: To characterise the association between 18-month autism traits and clinical, socio-demographic, and parental factors. Design: This is a cohort study of toddlers (n=536). Clinical, socio-demographic, and parental information was collected at birth (gestational age at birth, sex, maternal body mass index, age, parental education level, parental first language, parental history of neurodevelopmental disorders) and at 18 months (parent cohabiting status, two measures of social deprivation, three measures of maternal parenting style, and a measure of maternal postnatal depression). General neurodevelopment was assessed with the Bayley Scales of Infant and Toddler Development, 3rd Edition (BSID-III), and autism traits were assessed using the Quantitative Checklist for Autism in Toddlers (Q-CHAT). Multivariable models were used to identify associations between variables and Q-CHAT. A model including BSID-III was used to identify factors associated with Q-CHAT independent of general neurodevelopment. Models were also evaluated addressing variable collinearity with principal component analysis (PCA). Setting: Single centre (London, UK). Participants: Sub-sample from the developing Human Connectome Project (dHCP). Results: A multivariable model explained 20% of Q-CHAT variance, with four individually significant variables (two measures of parenting style and two measures of socio-economic deprivation). After adding general neurodevelopment into the model 37% of Q-CHAT variance was explained, with three individually significant variables (two measures of parenting style and one measure of language development). After addressing variable collinearity with PCA, experience of early life adversity was positively correlated with Q-CHAT score via a single principal component, independently of general neurodevelopment. Neither sex nor family history of autism were associated with Q-CHAT score. Conclusions and Relevance: Our findings question whether potential autism diagnoses are being missed in more socially deprived groups, or if there are unidentified factors influencing the likelihood of transitioning from early traits at age 18 months to a clinical autism diagnosis in childhood.

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Reliability and Validity of the Korean Translation of Quantitative Checklist for Autism in Toddlers: A Preliminary Study

Cited by 9 publications

References 6 publications

Autism screening and conditional cash transfers in Chile: Using the Quantitative Checklist (Q-CHAT) for early autism detection in a low resource setting

Autism screening and conditional cash transfers in Chile: Using the Quantitative Checklist (Q-CHAT) for early autism detection in a low resource setting

Symptoms of Autism Spectrum Disorders Measured by the Qualitative Checklist for Autism in Toddlers in a Large Sample of Polish Toddlers

Clinical, socio-demographic, and parental correlates of early autism traits in a community cohort

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