2014
DOI: 10.4172/2155-6148.1000437
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Remifentanil and Sufentanil Preserve Left Ventricular Systolic and Diastolic Function in Patients with Ischemic Heart Disease-A Randomised Comparative Study

Abstract: Although the impact of drugs on cardiac function seems unchanged by standard haemodynamic measurements, it might be followed by injurious stress and deterioration of myocardial function as stable conventional monitoring not necessarily represent unaffected function. The aim of the study was to assess changes in global haemodynamic measures, primarily by changes in cardiac index, and contemporary indices of LV systolic and diastolic function during induction of anaesthesia with remifentanil compared to sufentan… Show more

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Cited by 5 publications
(3 citation statements)
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“…In an investigation by Frederiksen et al, these findings could not be confirmed (30). The authors showed that sufentanil and remifentanil do not affect left ventricular global longitudinal strain (30) (36,37). In addition, conflicting data exist about the lack of correlation of the TAPSE with cardiac MRI-derived RV ejection fraction (38,39).…”
Section: Observer Variabilitymentioning
confidence: 95%
“…In an investigation by Frederiksen et al, these findings could not be confirmed (30). The authors showed that sufentanil and remifentanil do not affect left ventricular global longitudinal strain (30) (36,37). In addition, conflicting data exist about the lack of correlation of the TAPSE with cardiac MRI-derived RV ejection fraction (38,39).…”
Section: Observer Variabilitymentioning
confidence: 95%
“…In a study during anesthesia induction in pediatric cardiac patients, left ventricular ejection fraction decreased after administration of sufentanil or fentanyl (29). In an investigation by Frederiksen et al, these findings could not be confirmed (30). The authors showed that sufentanil and remifentanil do not affect left ventricular global longitudinal strain (30) (36,37).…”
Section: Observer Variabilitymentioning
confidence: 95%
“…44,45 Dexmedetomidine during transvenous aortic valve replacement appears to cause more hypotension and bradycardia than propofol with comparable post-procedure outcomes. 46 The lack of evidence precludes the formulation of specific recommendations in valvular heart disease.…”
Section: Sedation In the Failing Heartmentioning
confidence: 99%